Publications by authors named "Johan Staaf"

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Multi-omic profiling of squamous cell lung cancer identifies metabolites and related genes associated with squamous cell carcinoma.
Johan Staaf, Daniel Ehinger, Hans Brunnström, Mats Jönsson, Frida Rosengren

Mol Oncol· December 2025

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Stand-alone Transcriptional Immune Response Prediction in Primary Triple-Negative Breast Cancer.
Suze Roostee, Fredrika Killander, Hani Saghir, Deborah F Nacer, Jari Häkkinen, Johan Staaf

Cancer Res Commun· December 2025

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Molecular profiling of the Basal-like intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer.
Lennart Hohmann, Deborah F Nacer, Mattias Aine, Yasin Memari, Daniella Black, Johan Staaf

Genome Med· December 2025

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Clinical potential of whole-genome data linked to mortality statistics in patients with breast cancer in the UK: a retrospective analysis.
Daniella Black, Helen Ruth Davies, Gene Ching Chiek Koh, Lucia Chmelova, Marko Cubric, Johan Staaf

Lancet Oncol· November 2025

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Gene expression-based identification of prognostic markers in lung adenocarcinoma.
Annette Salomonsson, Daniel Ehinger, Mats Jönsson, Johan Botling, Patrick Micke, Johan Staaf

PLoS One· May 2025

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Evaluation of alternative prognostic thresholds for SP142 and 22C3 immunohistochemical PD-L1 expression in triple-negative breast cancer: results from a population-based cohort.
Gudbjörg Sigurjonsdottir, Tommaso De Marchi, Anna Ehinger, Johan Hartman, Susann Ullén, Johan Staaf

Breast Cancer Res Treat· April 2025

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Genomic characterization of the HER2-enriched intrinsic molecular subtype in primary ER-positive HER2-negative breast cancer.
Lennart Hohmann, Kristin Sigurjonsdottir, Ana Bosch Campos, Deborah F Nacer, Srinivas Veerla, Johan Staaf

Nat Commun· March 2025

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The DNA methylation landscape of primary triple-negative breast cancer.
Mattias Aine, Deborah F Nacer, Elsa Arbajian, Srinivas Veerla, Anna Karlsson, Johan Staaf

Nat Commun· March 2025

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FHL2 expression by cancer-associated fibroblasts promotes metastasis and angiogenesis in lung adenocarcinoma.
Ryu Kanzaki, Steven Reid, Paulina Bolivar, Jonas Sjölund, Johan Staaf

Int J Cancer· January 2025

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A two-phase epigenome-wide four-way gene-smoking interaction study of overall survival for early-stage non-small cell lung cancer.
Leyi Chen, Xiang Wang, Ning Xie, Zhongwen Zhang, Xiaowen Xu, Johan Staaf

Mol Oncol· January 2025

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RET inhibition overcomes resistance to combined CDK4/6 inhibitor and endocrine therapy in ER+ breast cancer.
Charlotte K Kindt, Sidse Ehmsen, Sofie Traynor, Benedetta Policastro, Nikoline Nissen, Johan Staaf

Front Oncol· January 2025

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Genomic alterations associated with resistance and circulating tumor DNA dynamics for early detection of progression on CDK4/6 inhibitor in advanced breast cancer.
Charlotte K Kindt, Carla L Alves, Sidse Ehmsen, Amalie Kragh, Thomas Reinert, Johan Staaf

Int J Cancer· December 2024

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The analytical and clinical validity of AI algorithms to score TILs in TNBC: can we use different machine learning models interchangeably?
Joan Martínez Vidal, Nikos Tsiknakis, Johan Staaf, Ana Bosch, Anna Ehinger

EClinicalMedicine· December 2024

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Tumour immune characterisation of primary triple-negative breast cancer using automated image quantification of immunohistochemistry-stained immune cells.
Suze Roostee, Daniel Ehinger, Mats Jönsson, Bengt Phung, Göran Jönsson, Johan Staaf

Sci Rep· September 2024

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Tumor purity estimated from bulk DNA methylation can be used for adjusting beta values of individual samples to better reflect tumor biology.
Iñaki Sasiain, Deborah F Nacer, Mattias Aine, Srinivas Veerla, Johan Staaf

NAR Genom Bioinform· September 2024

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Diagnostic gastrointestinal markers in primary lung cancer and pulmonary metastases.
Karina Malmros, Andreas Lindholm, Halla Vidarsdottir, Karin Jirström, Björn Nodin, Johan Staaf

Virchows Arch· August 2024

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Current and emerging sequencing-based tools for precision cancer medicine.
Anders Edsjö, David Gisselsson, Johan Staaf, Louise Holmquist, Thoas Fioretos

Mol Aspects Med· April 2024

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A 14-gene B-cell immune signature in early-stage triple-negative breast cancer (TNBC): a pooled analysis of seven studies.
Benedetta Conte, Fara Brasó-Maristany, Adela Rodríguez Hernández, Tomás Pascual, Guillermo Villacampa, Johan Staaf

EBioMedicine· April 2024

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Kataegis in clinical and molecular subgroups of primary breast cancer.
Srinivas Veerla, Johan Staaf

NPJ Breast Cancer· April 2024

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Disruption of the TP53 locus in osteosarcoma leads to TP53 promoter gene fusions and restoration of parts of the TP53 signalling pathway.
Karim H Saba, Valeria Difilippo, Michal Kovac, Louise Cornmark, Linda Magnusson, Johan Staaf

J Pathol· February 2024

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Improved detection of clinically relevant fusion transcripts in cancer by machine learning classification.
Völundur Hafstað, Jari Häkkinen, Malin Larsson, Johan Staaf, Johan Vallon-Christersson

BMC Genomics· December 2023

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Comparison of SP142 and 22C3 PD-L1 assays in a population-based cohort of triple-negative breast cancer patients in the context of their clinically established scoring algorithms.
Gudbjörg Sigurjonsdottir, Tommaso De Marchi, Anna Ehinger, Johan Hartman, Ana Bosch, Johan Staaf

Breast Cancer Res· October 2023

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Perturbation and stability of PAM50 subtyping in population-based primary invasive breast cancer.
Srinivas Veerla, Lennart Hohmann, Deborah F Nacer, Johan Vallon-Christersson, Johan Staaf

NPJ Breast Cancer· October 2023

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Correction: Complement inhibitor CSMD1 modulates epidermal growth factor receptor oncogenic signaling and sensitizes breast cancer cells to chemotherapy.
Chrysostomi Gialeli, Emre Can Tuysuz, Johan Staaf, Safa Guleed, Veronika Paciorek

J Exp Clin Cancer Res· May 2023

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Molecular characteristics of breast tumors in patients screened for germline predisposition from a population-based observational study.
Deborah F Nacer, Johan Vallon-Christersson, Nicklas Nordborg, Hans Ehrencrona, Anders Kvist, Johan Staaf

Genome Med· April 2023

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