Publications by authors named "Johan van Meerloo"

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T-cell and antibody responses in immunocompromised patients with hematologic malignancies indicate strong potential of SARS-CoV-2 mRNA vaccines.
Cilia R Pothast, Quincy Hofsink, Sabine Haggenburg, Romy C Dijkland, Marian Van de Meent, Johan Van Meerloo

Haematologica· November 2025

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High immunoproteasome and low constitutive proteasome subunit levels correlate with sensitivity to bortezomib-containing chemotherapy: update from the Children's Oncology Group AALL1231 trial.
Margot S F Roeten, Johan Van Meerloo, Suzanne N Van Dijk, Zinia Kwidama, Gaye Jenkins

Haematologica· June 2025

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Unveiling the Anti-Angiogenic Potential of Small-Molecule (Kinase) Inhibitors for Application in Rheumatoid Arthritis.
Fatemeh Khodadust, Eva M L Philippon, Maarten M Steinz, Jan Piet van Hamburg, Johan van Meerloo

Cells· January 2025

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Fourth mRNA COVID-19 vaccination in immunocompromised patients with haematological malignancies (COBRA KAI): a cohort study.
Quincy Hofsink, Sabine Haggenburg, Birgit I Lissenberg-Witte, Annoek E C Broers, Jaap A van Doesum, Johan van Meerloo

EClinicalMedicine· July 2023

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Statins markedly potentiate aminopeptidase inhibitor activity against (drug-resistant) human acute myeloid leukemia cells.
Gerrit Jansen, Marjon Al, Yehuda G Assaraf, Sarah Kammerer, Johan van Meerloo

Cancer Drug Resist· July 2023

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Quantitative analysis of mRNA-1273 COVID-19 vaccination response in immunocompromised adult hematology patients.
Sabine Haggenburg, Birgit I Lissenberg-Witte, Rob S van Binnendijk, Gerco den Hartog, Michel S Bhoekhan, Johan van Meerloo

Blood Adv· March 2022

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Pre-Clinical Evaluation of the Proteasome Inhibitor Ixazomib against Bortezomib-Resistant Leukemia Cells and Primary Acute Leukemia Cells.
Margot S F Roeten, Johan van Meerloo, Zinia J Kwidama, Giovanna Ter Huizen, Wouter H Segerink

Cells· March 2021

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Crizotinib sensitizes the erlotinib resistant HCC827GR5 cell line by influencing lysosomal function.
Nele Van Der Steen, Kaylee Keller, Henk Dekker, Letizia Porcelli, Richard J Honeywell, Johan Van Meerloo

J Cell Physiol· November 2020

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Phosphotyrosine-based Phosphoproteomics for Target Identification and Drug Response Prediction in AML Cell Lines.
Carolien van Alphen, Jacqueline Cloos, Robin Beekhof, David G J Cucchi, Sander R Piersma, Johan van Meerloo

Mol Cell Proteomics· May 2020

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Monocytes and Granulocytes Reduce CD38 Expression Levels on Myeloma Cells in Patients Treated with Daratumumab.
Jakub Krejcik, Kris A Frerichs, Inger S Nijhof, Berris van Kessel, Jeroen F van Velzen, Johan van Meerloo

Clin Cancer Res· December 2017

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(Immuno)proteasomes as therapeutic target in acute leukemia.
Jacqueline Cloos, Margot Sf Roeten, Niels E Franke, Johan van Meerloo, Sonja Zweegman

Cancer Metastasis Rev· December 2017

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Exocytosis of polyubiquitinated proteins in bortezomib-resistant leukemia cells: a role for MARCKS in acquired resistance to proteasome inhibitors.
Niels E Franke, Gertjan L Kaspers, Yehuda G Assaraf, Johan van Meerloo, Denise Niewerth

Oncotarget· November 2016

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Proteasome subunit expression analysis and chemosensitivity in relapsed paediatric acute leukaemia patients receiving bortezomib-containing chemotherapy.
Denise Niewerth, Gertjan J L Kaspers, Gerrit Jansen, Johan van Meerloo, Sonja Zweegman

J Hematol Oncol· September 2016

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Exosomes Secreted by Apoptosis-Resistant Acute Myeloid Leukemia (AML) Blasts Harbor Regulatory Network Proteins Potentially Involved in Antagonism of Apoptosis.
Anna Wojtuszkiewicz, Gerrit J Schuurhuis, Floortje L Kessler, Sander R Piersma, Jaco C Knol, Johan van Meerloo

Mol Cell Proteomics· April 2016

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Antileukemic activity and mechanism of drug resistance to the marine Salinispora tropica proteasome inhibitor salinosporamide A (Marizomib).
Denise Niewerth, Gerrit Jansen, Lesley F V Riethoff, Johan van Meerloo, Andrew J Kale

Mol Pharmacol· July 2014

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Anti-leukemic activity and mechanisms underlying resistance to the novel immunoproteasome inhibitor PR-924.
Denise Niewerth, Johan van Meerloo, Gerrit Jansen, Yehuda G Assaraf, Tessa C Hendrickx

Biochem Pharmacol· May 2014

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Interferon-γ-induced upregulation of immunoproteasome subunit assembly overcomes bortezomib resistance in human hematological cell lines.
Denise Niewerth, Gertjan J L Kaspers, Yehuda G Assaraf, Johan van Meerloo, Christopher J Kirk

J Hematol Oncol· January 2014

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Higher ratio immune versus constitutive proteasome level as novel indicator of sensitivity of pediatric acute leukemia cells to proteasome inhibitors.
Denise Niewerth, Niels E Franke, Gerrit Jansen, Yehuda G Assaraf, Johan van Meerloo

Haematologica· December 2013

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Overcoming bortezomib resistance in human B cells by anti-CD20/rituximab-mediated complement-dependent cytotoxicity and epoxyketone-based irreversible proteasome inhibitors.
Sue Ellen Verbrugge, Marjon Al, Yehuda G Assaraf, Denise Niewerth, Johan van Meerloo

Exp Hematol Oncol· January 2013

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Proteasome-based mechanisms of intrinsic and acquired bortezomib resistance in non-small cell lung cancer.
Leonie H A M de Wilt, Gerrit Jansen, Yehuda G Assaraf, Johan van Meerloo, Jacqueline Cloos

Biochem Pharmacol· January 2012

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Cell sensitivity assays: the MTT assay.
Johan van Meerloo, Gertjan J L Kaspers, Jacqueline Cloos

Methods Mol Biol· August 2011

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Immortalization of oral keratinocytes by functional inactivation of the p53 and pRb pathways.
Serge J Smeets, Marlon van der Plas, Tieneke B M Schaaij-Visser, Eva A M van Veen, Johan van Meerloo

Int J Cancer· April 2011

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