Publications by authors named "John A Cook"

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Rapamycin Reduces Carcinogenesis and Enhances Survival in Mice when Administered after Nonlethal Total-Body Irradiation.
Anastasia L Sowers, Sangeeta Gohain, Elijah F Edmondson, Rajani Choudhuri, Murali C Krishna, John A Cook

Radiat Res· October 2024

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Sepsis-Induced Coagulopathy and Disseminated Intravascular Coagulation: What We Need to Know and How to Manage for Prolonged Casualty Care.
Jason J Nam, An-Kwok Ian Wong, David Cantong, John Alexander Cook, Zachary Andrews

J Spec Oper Med· June 2023

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The effect of modulation of gut microbiome profile on radiation-induced carcinogenesis and survival.
John A Cook, Anastasia L Sowers, Rajani Choudhuri, Chandramouli Gadisetti, Elijah F Edmondson

J Radiat Res· January 2023

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The antioxidant tempol transforms gut microbiome to resist obesity in female C3H mice fed a high fat diet.
Rajani Choudhuri, Anastasia L Sowers, G V R Chandramouli, Janet Gamson, Murali C Krishna, John A Cook

Free Radic Biol Med· January 2022

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Pharmacological Inhibition of HSP90 Radiosensitizes Head and Neck Squamous Cell Carcinoma Xenograft by Inhibition of DNA Damage Repair, Nucleotide Metabolism, and Radiation-Induced Tumor Vasculogenesis.
Sarwat Naz, Andrew J Leiker, Rajani Choudhuri, Olivia Preston, Anastasia L Sowers, John A Cook

Int J Radiat Oncol Biol Phys· August 2021

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Radiation-Induced Senescence Reprograms Secretory and Metabolic Pathways in Colon Cancer HCT-116 Cells.
Chandrasekharam N Nagineni, Sarwat Naz, Rajani Choudhuri, Gadisetti V R Chandramouli, Murali C Krishna, John A Cook

Int J Mol Sci· May 2021

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Abemaciclib: A multi-functional radiation modifier.
Sarwat Naz, John A Cook, James B Mitchell

Oncotarget· February 2019

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Abemaciclib, a Selective CDK4/6 Inhibitor, Enhances the Radiosensitivity of Non-Small Cell Lung Cancer and .
Sarwat Naz, Anastasia Sowers, Rajani Choudhuri, Maria Wissler, Janet Gamson, John A Cook

Clin Cancer Res· August 2018

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Cancer Incidence in C3H Mice Protected from Lethal Total-Body Radiation after Amifostine.
John A Cook, Sarwat Naz, Miriam R Anver, Anastasia L Sowers, Kristin Fabre

Radiat Res· May 2018

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Mass Spectrometry-Based Metabolomics Identifies Longitudinal Urinary Metabolite Profiles Predictive of Radiation-Induced Cancer.
John A Cook, Gadisetti V R Chandramouli, Miriam R Anver, Anastasia L Sowers, Angela Thetford

Cancer Res· March 2016

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Radiation Enhancement of Head and Neck Squamous Cell Carcinoma by the Dual PI3K/mTOR Inhibitor PF-05212384.
Andrew J Leiker, William DeGraff, Rajani Choudhuri, Anastasia L Sowers, Angela Thetford, John A Cook

Clin Cancer Res· June 2015

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The nitroxide radical TEMPOL prevents obesity, hyperlipidaemia, elevation of inflammatory cytokines, and modulates atherosclerotic plaque composition in apoE-/- mice.
Christine H J Kim, James B Mitchell, Christina A Bursill, Anastasia L Sowers, Angela Thetford, John A Cook

Atherosclerosis· May 2015

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Factor XIIa inhibition by Infestin-4: in vitro mode of action and in vivo antithrombotic benefit.
Yiming Xu, Tian-Quan Cai, Gino Castriota, Yuchen Zhou, Lizbeth Hoos, John A Cook

Thromb Haemost· April 2014

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Identification of 2-aminooxazole amides as acyl-CoA: diacylglycerol acyltransferase 1 (DGAT1) inhibitors through scaffold hopping strategy.
Hyunjin M Kim, Michelle D Smith, Jae-Hun Kim, Mary Ann Caplen, Tin Yau Chan, John A Cook

Bioorg Med Chem Lett· December 2013

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A molecular, phylogenetic and functional study of the mRNA truncated isoform during embryonic development reveals an editing-independent function.
Sushmita Ghosh, Yaqi Wang, John A Cook, Lea Chhiba, Jack C Vaughn

Open J Anim Sci· November 2013

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Metabolomics reveals that tumor xenografts induce liver dysfunction.
Fei Li, Andrew D Patterson, Kristopher W Krausz, Changtao Jiang, Huichang Bi, John A Cook

Mol Cell Proteomics· August 2013

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Stable isotope- and mass spectrometry-based metabolomics as tools in drug metabolism: a study expanding tempol pharmacology.
Fei Li, Xiaoyan Pang, Kristopher W Krausz, Changtao Jiang, Chi Chen, John A Cook

J Proteome Res· March 2013

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The antioxidant tempol reduces carcinogenesis and enhances survival in mice when administered after nonlethal total body radiation.
James B Mitchell, Miriam R Anver, Anastasia L Sowers, Philip S Rosenberg, Maria Figueroa, John A Cook

Cancer Res· September 2012

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Guggulsterone-mediated enhancement of radiosensitivity in human tumor cell lines.
Rajani Choudhuri, William Degraff, Janet Gamson, James B Mitchell, John A Cook

Front Oncol· August 2012

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Pharmacological protection from radiation ± cisplatin-induced oral mucositis.
Ana P Cotrim, Masanobu Yoshikawa, Abraham N Sunshine, Changyu Zheng, Anastasia L Sowers, John A Cook

Int J Radiat Oncol Biol Phys· July 2012

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The effects of resveratrol and selected metabolites on the radiation and antioxidant response.
Kristin M Fabre, Keita Saito, William DeGraff, Anastasia L Sowers, Angela Thetford, John A Cook

Cancer Biol Ther· November 2011

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Inhibition of adipogenesis by Tempol in 3T3-L1 cells.
Yuval Samuni, John A Cook, Rajani Choudhuri, William Degraff, Anastasia L Sowers

Free Radic Biol Med· August 2010

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Improvement and induction property of radiation-responsive promoter through DNA shuffling of 5'-flanking regions of the human p21 gene.
Go Kagiya, Ryohei Ogawa, John A Cook, Rajani Choudhuri, Masanori Hatashita

J Biosci Bioeng· July 2010

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In vitro and in vivo radiation sensitization of human tumor cells by a novel checkpoint kinase inhibitor, AZD7762.
James B Mitchell, Rajani Choudhuri, Kristin Fabre, Anastasia L Sowers, Deborah Citrin, John A Cook

Clin Cancer Res· April 2010

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