Publications by authors named "John Busby"

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Response to Biologics Along a Gradient of T2 Involvement in Patients With Severe Asthma: A Data-Driven Biomarker Clustering Approach.
Eileen Wang, William Henley, Désirée Larenas-Linnemann, Lakmini Bulathsinhala, Trung N Tran, John Busby

J Allergy Clin Immunol Pract· December 2025

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Observational Analysis of Biological Remission as a Treatment Target for Severe Asthma: UK Severe Asthma Registry.
P Jane McDowell, Charlene Redmond, John Busby, Pujan Patel, David J Jackson

J Allergy Clin Immunol Pract· December 2025

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Disease Trajectory and Treatment Escalation in Asthma: A Retrospective Analysis of Data From the Optimum Patient Care Research Database (OPCRD).
Matthew Chad Eastwood, Ron McDowell, John Busby, Pamela Jane McDowell, David Price

J Allergy Clin Immunol Pract· November 2025

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Effects of Obesity on Response to Asthma Biologic Treatment: Longitudinal Data From the United Kingdom Severe Asthma Registry.
Sherif Gonem, Charlene Redmond, John Busby, Pujan Patel, David J Jackson

J Allergy Clin Immunol Pract· November 2025

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Analysis of airway inflammation demonstrates a mechanism for T2-biologic failure in asthma.
P Jane McDowell, Adnan Azim, John Busby, Sarah Diver, Freda Yang

J Allergy Clin Immunol· October 2025

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Investigating the Association Between Biologic Initiation and Medication Adherence in Severe Asthma: An Analysis of Linked Data.
Amy Shackleford, Liam G Heaney, P Jane McDowell, Gwyneth A Davies, Claire Butler, John Busby

J Allergy Clin Immunol Pract· October 2025

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Long-Term Clinical Remission on Biologics: An Analysis of Real-World Data From the UK Severe Asthma Registry.
Charlene Redmond, John Busby, Adel H Mansur, Mitesh Patel, Pujan H Patel

J Allergy Clin Immunol Pract· October 2025

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Impact of Biologics Initiation on Oral Corticosteroid Use in the International Severe Asthma Registry and the Optimum Patient Care Research Database: A Pooled Analysis of Real-World Data.
Wenjia Chen, Trung N Tran, John Townend, George C Christoff, Ming-Ju Tsai, John Busby

J Allergy Clin Immunol Pract· August 2025

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Prediction Pathway for Severe Asthma Exacerbations: A Bayesian Network Analysis.
Chandra Prakash Yadav, Atlanta Chakraborty, David B Price, Laura Huey Mien Lim, Yah Ru Juang, John Busby

Chest· August 2025

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Exploring the Long-Term Utility of Remotely Monitored FeNO Suppression Testing in Severe Asthma.
John Busby, Joshua Holmes, Mohammed Almutairi, Irene Berrar-Torre, Claire Butler

J Allergy Clin Immunol Pract· July 2025

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Prevention of Cardiovascular and Other Systemic Adverse Outcomes in Patients with Asthma Treated with Biologics.
Mohsen Sadatsafavi, Trung N Tran, Ghislaine Scelo, Ming-Ju Tsai, John Busby

Am J Respir Crit Care Med· July 2025

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Urinary thromboxane and isoprostane levels are elevated in symptom-high T2-biomarker-low severe asthma.
Matthew Chad Eastwood, John Busby, Johan Kolmert, Javier Zurita, Sven-Erik Dahlén

ERJ Open Res· July 2025

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Incidence and prevalence of asthma, chronic obstructive pulmonary disease and interstitial lung disease between 2004 and 2023: harmonised analyses of longitudinal cohorts across England, Wales, South-East Scotland and Northern Ireland.
Hannah Whittaker, Adriana Kramer Fiala Machado, Sara Hatam, Sarah Cook, Sean Scully, John Busby

Thorax· June 2025

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Real-world uptake of nirsevimab, RSV maternal vaccine, and RSV vaccines for older adults: a systematic review and meta-analysis.
Daira Trusinska, Bohee Lee, Sohail Ferdous, Harley H Y Kwok, Becky Gordon, John Busby

EClinicalMedicine· June 2025

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Pre-biologic assessment of adherence in severe asthma and association with biologic continuation: a UK Severe Asthma Registry Study.
Freda Yang, Ronald McDowell, John Busby, Anna Claire Murphy, Pujan H Patel

BMJ Open Respir Res· June 2025

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Exploring the carbon footprint of severe asthma and change after biologic therapy initiation: an analysis of Northern Irish data.
John Busby, Mina Khezrian, Soram Patel, Trung N Tran, Kirsty Rhodes

ERJ Open Res· May 2025

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International Severe Asthma Registry (ISAR): 2017-2024 Status and Progress Update.
Désirée Larenas-Linnemann, Chin Kook Rhee, Alan Altraja, John Busby, Trung N Tran

Tuberc Respir Dis (Seoul)· April 2025

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Longitudinal Assessment of Glucocorticoid Toxicity Reduction in Patients With Severe Asthma Treated With Biologic Therapies.
P Jane McDowell, John Busby, John H Stone, Claire A Butler, Liam G Heaney

J Allergy Clin Immunol Pract· February 2025

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Response and remission in asthma with tezepelumab: overlapping concepts informing on type-2 inflammatory-dependent treatment effects.
Samuel Mailhot-Larouche, John Busby, Simon Couillard

Eur Respir J· February 2025

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Clinical remission attainment, definitions, and correlates among patients with severe asthma treated with biologics: a systematic review and meta-analysis.
Amy Shackleford, Liam G Heaney, Charlene Redmond, P Jane McDowell, John Busby

Lancet Respir Med· January 2025

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Airway proteomics reveals broad residual anti-inflammatory effects of prednisolone in mepolizumab-treated asthma.
Imran Howell, Freda Yang, Vanessa Brown, Jennifer Cane, Emanuele Marchi, John Busby

J Allergy Clin Immunol· November 2024

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Real-world biologics response and super-response in the International Severe Asthma Registry cohort.
Eve Denton, Mark Hew, Matthew J Peters, John W Upham, Lakmini Bulathsinhala, John Busby

Allergy· October 2024

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Clinical and Economic Burden of Severe Asthma With Low Blood Eosinophil Counts.
John Busby, Shruti Menon, Neil Martin, Joe Lipworth, Ruiqi Zhang

J Allergy Clin Immunol Pract· October 2024

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Impact of comorbidities on EQ-5D quality-of-life index in severe asthma.
Paul E Pfeffer, Thomas Brown, Rekha Chaudhuri, Shoaib Faruqi, Robin Gore, John Busby

J Allergy Clin Immunol Glob· August 2024

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Clinical remission with biologic therapies in severe asthma: a matter of definition.

Eur Respir J· June 2024

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