Publications by authors named "John Chappell"

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Addressing nonspecific interactions in a Gyrolab anti-drug antibody (ADA) assay: a case study on method optimization to improve repeatability.
Eliza Kęsy-Siwik, John Chappell, Dorota Jaros, Małgorzata Urbaniak, Agata Sakowicz

Bioanalysis· December 2025

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Optimized enrichment of murine blood-brain barrier vessels with a critical focus on network hierarchy in post-collection analysis.
Hanaa Abdelazim, Audra Barnes, James Stupin, Ranah Hasson, Carmen Muñoz-Ballester, John C Chappell

Sci Rep· May 2025

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Pericyte and Endothelial Cell Responses within Murine Cerebral Capillaries After Blood Flow Cessation.
Hanaa Abdelazim, Mayd Alsalman, Mason Wheeler, Jessica Pfleger, John C Chappell

bioRxiv· May 2025

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Optimized Enrichment of Murine Blood-Brain Barrier Vessels with a Critical Focus on Network Hierarchy in Post-Collection Analysis.
Hanaa Abdelazim, Audra Barnes, James Stupin, Ranah Hasson, Carmen Muñoz-Ballester, John C Chappell

bioRxiv· September 2024

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Connexin 43 across the Vasculature: Gap Junctions and Beyond.
Meghan W Sedovy, Xinyan Leng, Melissa R Leaf, Farwah Iqbal, Laura Beth Payne, John C Chappell

J Vasc Res· September 2023

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A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and Is Upregulated during Hypoxia and Aging.
Laura Beth Payne, Hanaa Abdelazim, Maruf Hoque, Audra Barnes, Zuzana Mironovova, John C Chappell

Biomolecules· April 2023

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A Soluble Platelet-Derived Growth Factor Receptor-β Originates via Pre-mRNA Splicing in the Healthy Brain and is Differentially Regulated during Hypoxia and Aging.
Laura Beth Payne, Hanaa Abdelazim, Maruf Hoque, Audra Barnes, Zuzana Mironovova, John C Chappell

bioRxiv· February 2023

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Evaluating cell viability, capillary perfusion, and collateral tortuosity in an ex vivo mouse intestine fluidics model.
Caroline E Willi, Hanaa Abdelazim, John C Chappell

Front Bioeng Biotechnol· December 2022

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Pericyte heterogeneity identified by 3D ultrastructural analysis of the microvessel wall.
Hanaa Abdelazim, Laura Beth Payne, Kyle Nolan, Karan Paralkar, Vanessa Bradley, John C Chappell

Front Physiol· December 2022

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Pericyte Progenitor Coupling to the Emerging Endothelium During Vasculogenesis via Connexin 43.
Laura Beth Payne, Bhanu P Tewari, Logan Dunkenberger, Samantha Bond, Alyssa Savelli, John C Chappell

Arterioscler Thromb Vasc Biol· April 2022

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Comparing singlet and duplicate immunogenicity assay in human plasma for pembrolizumab using Gyrolab.
Johannes L Stanta, Hannah Craig, Christopher Smith, John Chappell

Bioanalysis· June 2021

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The cerebral microvasculature: Basic and clinical perspectives on stroke and glioma.
Maruf M Hoque, Hanaa Abdelazim, Clifton Jenkins-Houk, Dawn Wright, Biraj M Patel, John C Chappell

Microcirculation· April 2021

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Pericyte migration and proliferation are tightly synchronized to endothelial cell sprouting dynamics.
Laura Beth Payne, Jordan Darden, Ariana D Suarez-Martinez, Huaning Zhao, Alissa Hendricks, John C Chappell

Integr Biol (Camb)· February 2021

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Pericytes in Vascular Development.
Laura Beth Payne, Maruf Hoque, Clifton Houk, Jordan Darden, John C Chappell

Curr Tissue Microenviron Rep· September 2020

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Pericyte Bridges in Homeostasis and Hyperglycemia.
Bruce A Corliss, H Clifton Ray, Richard W Doty, Corbin Mathews, Natasha Sheybani, John Chappell

Diabetes· July 2020

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Specific labeling of synaptic schwann cells reveals unique cellular and molecular features.
Ryan Castro, Thomas Taetzsch, Sydney K Vaughan, Kerilyn Godbe, John Chappell

Elife· June 2020

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Recommendations for the Development and Validation of Immunogenicity Assays in Support of Biosimilar Programs.
Francesca Civoli, Aparna Kasinath, Xiao-Yan Cai, Meenu Wadhwa, Andrew Exley, John Chappell

AAPS J· December 2019

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The pericyte microenvironment during vascular development.
Laura B Payne, Huaning Zhao, Carissa C James, Jordan Darden, David McGuire, John C Chappell

Microcirculation· November 2019

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Blood Vessel Patterning on Retinal Astrocytes Requires Endothelial Flt-1 (VEGFR-1).
John C Chappell, Jordan Darden, Laura Beth Payne, Kathryn Fink, Victoria L Bautch

J Dev Biol· September 2019

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Applications of Ultrasound to Stimulate Therapeutic Revascularization.
Catherine M Gorick, John C Chappell, Richard J Price

Int J Mol Sci· June 2019

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Microvascular bioengineering: a focus on pericytes.
Huaning Zhao, John C Chappell

J Biol Eng· March 2019

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Excess vascular endothelial growth factor-A disrupts pericyte recruitment during blood vessel formation.
Jordan Darden, Laura Beth Payne, Huaning Zhao, John C Chappell

Angiogenesis· February 2019

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Hypoxia, angiogenesis, and metabolism in the hereditary kidney cancers.
John C Chappell, Laura Beth Payne, W Kimryn Rathmell

J Clin Invest· February 2019

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Establishment and characterization of an embryonic pericyte cell line.
Huaning Zhao, Jordan Darden, John C Chappell

Microcirculation· July 2018

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Von Hippel-Lindau mutations disrupt vascular patterning and maturation via Notch.
Alexandra Arreola, Laura Beth Payne, Morgan H Julian, Aguirre A de Cubas, Anthony B Daniels, John C Chappell

JCI Insight· February 2018

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