Publications by authors named "John D Cleary"

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Dysregulation of alternative splicing is a transcriptomic feature of patient-derived fibroblasts from CAG repeat expansion spinocerebellar ataxias.
Asmer Aliyeva, Claudia D Lennon, John D Cleary, Hannah K Shorrock, J Andrew Berglund

Hum Mol Genet· February 2025

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Alternative splicing dysregulation across tissue and therapeutic approaches in a mouse model of myotonic dystrophy type 1.
Sawyer M Hicks, Jesus A Frias, Subodh K Mishra, Marina Scotti, Derek R Muscato, John D Cleary

Mol Ther Nucleic Acids· December 2024

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Expression levels of core spliceosomal proteins modulate the MBNL-mediated spliceopathy in DM1.
Jiss M Louis, Jesus A Frias, Jacob H Schroader, Lindsey A Jones, Emily E Davey, John D Cleary

Hum Mol Genet· November 2024

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CAG repeat-selective compounds reduce abundance of expanded CAG RNAs in patient cell and murine models of SCAs.
Hannah K Shorrock, Asmer Aliyeva, Jesus A Frias, Victoria A DeMeo, Claudia D Lennon, John D Cleary

bioRxiv· August 2024

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Counting the Cost of Daptomycin Versus Vancomycin in Hospitalized Patients: A Cost Minimization Analysis.
Jamie L Wagner, Bruce M Jones, Kayla R Stover, John D Cleary, Christopher M Bland

Open Forum Infect Dis· May 2024

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Widespread alternative splicing dysregulation occurs presymptomatically in CAG expansion spinocerebellar ataxias.
Hannah K Shorrock, Claudia D Lennon, Asmer Aliyeva, Emily E Davey, Cristina C DeMeo, John D Cleary

Brain· February 2024

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Alternative Splicing Outcomes Across an RNA-Binding Protein Concentration Gradient.
Joseph A Ellis, Melissa A Hale, John D Cleary, Eric T Wang, J Andrew Berglund

J Mol Biol· August 2023

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Individual transcriptomic response to strength training for patients with myotonic dystrophy type 1.
Emily E Davey, Cécilia Légaré, Lori Planco, Sharon Shaughnessy, Claudia D Lennon, John Douglas Cleary

JCI Insight· July 2023

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Quercetin selectively reduces expanded repeat RNA levels in models of myotonic dystrophy.
Subodh K Mishra, Sawyer M Hicks, Jesus A Frias, Sweta Vangaveti, Masayuki Nakamori, John D Cleary

bioRxiv· February 2023

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Molecular characterization of myotonic dystrophy fibroblast cell lines for use in small molecule screening.
Jana R Jenquin, Alana P O'Brien, Kiril Poukalov, Yidan Lu, Jesus A Frias, John Douglas Cleary

iScience· May 2022

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Therapeutic strategies for C9orf72 amyotrophic lateral sclerosis and frontotemporal dementia.
Guillaume M Hautbergue, John D Cleary, Shu Guo, Laura P W Ranum

Curr Opin Neurol· October 2021

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The alternative initiation factor eIF2A plays key role in RAN translation of myotonic dystrophy type 2 CCUG•CAGG repeats.
Solaleh Khoramian Tusi, Lien Nguyen, Kiruphagaran Thangaraju, Jian Li, John D Cleary

Hum Mol Genet· May 2021

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Drug Screen Tugs at Common Thread for Repeat Disorders.
Kaalak Reddy, John Douglas Cleary, J Andrew Berglund

Trends Pharmacol Sci· February 2020

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The potential of engineered eukaryotic RNA-binding proteins as molecular tools and therapeutics.
Carl R Shotwell, John D Cleary, J Andrew Berglund

Wiley Interdiscip Rev RNA· January 2020

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A CTG repeat-selective chemical screen identifies microtubule inhibitors as selective modulators of toxic CUG RNA levels.
Kaalak Reddy, Jana R Jenquin, Ona L McConnell, John D Cleary, Jared I Richardson

Proc Natl Acad Sci U S A· October 2019

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Mitigating RNA Toxicity in Myotonic Dystrophy using Small Molecules.
Kaalak Reddy, Jana R Jenquin, John D Cleary, J Andrew Berglund

Int J Mol Sci· August 2019

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Repeat-Associated Non-ATG Translation: Molecular Mechanisms and Contribution to Neurological Disease.
Lien Nguyen, John Douglas Cleary, Laura P W Ranum

Annu Rev Neurosci· July 2019

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Abnormal nuclear aggregation and myotube degeneration in myotonic dystrophy type 1.
Yanlin Wang, Lei Hao, Hui Li, John D Cleary, Michael P Tomac

Neurol Sci· June 2019

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Systematic review of professional liability when prescribing β-lactams for patients with a known penicillin allergy.
Meghan N Jeffres, Elizabeth A Hall-Lipsy, S Travis King, John D Cleary

Ann Allergy Asthma Immunol· November 2018

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Repeat-associated non-ATG (RAN) translation.
John Douglas Cleary, Amrutha Pattamatta, Laura P W Ranum

J Biol Chem· October 2018

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All in the Family: Repeats and ALS/FTD.
Amrutha Pattamatta, John D Cleary, Laura P W Ranum

Trends Neurosci· May 2018

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Altered levels of the splicing factor muscleblind modifies cerebral cortical function in mouse models of myotonic dystrophy.
Gang Chen, Russell E Carter, John D Cleary, Tammy S Reid, Laura P Ranum

Neurobiol Dis· April 2018

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Intron retention induced by microsatellite expansions as a disease biomarker.
Łukasz J Sznajder, James D Thomas, Ellie M Carrell, Tammy Reid, Karen N McFarland, John D Cleary

Proc Natl Acad Sci U S A· April 2018

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Cardiac Safety of High-dose Micafungin.
Kayla R Stover, John D Cleary

J Pharmacol Pharmacother· January 2017

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