Publications by authors named "John D Clements"

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Protective antibodies against enterotoxigenic Escherichia coli are generated from heat-labile toxoid vaccination and exhibit subject- and vaccine-specific diversity.
Milton Maciel, Jordan C Scott, Robin L Baudier, John D Clements, Renee M Laird

Med Microbiol Immunol· February 2025

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A clade C HIV-1 vaccine protects against heterologous SHIV infection by modulating IgG glycosylation and T helper response in macaques.
Anusmita Sahoo, Andrew T Jones, Narayanaiah Cheedarla, Sailaja Gangadhara, Vicky Roy, John D Clements

Sci Immunol· July 2022

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Tackling the burden of mumps in the military: A report of the Defense Health Board.
John D Clements, Gregory H Gorman, Clarice N Waters, H Clifford Lane,

Vaccine· October 2021

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Elevated Extracellular cGMP Produced after Exposure to Enterotoxigenic Escherichia coli Heat-Stable Toxin Induces Epithelial IL-33 Release and Alters Intestinal Immunity.
Natalya I Motyka, Sydney R Stewart, Ian E Hollifield, Thomas R Kyllo, Joshua A Mansfield, John D Clements

Infect Immun· March 2021

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Comparative Evaluation of Prophylactic SIV Vaccination Modalities Administered to the Oral Cavity.
Omkar Chaudhary, Lingyun Wang, Deepanwita Bose, Vivek Narayan, Ming Te Yeh, John D Clements

AIDS Res Hum Retroviruses· December 2020

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Population Pharmacokinetics of Blinatumomab in Pediatric and Adult Patients with Hematological Malignancies.
John David Clements, Min Zhu, Mita Kuchimanchi, Bianca Terminello, Sameer Doshi

Clin Pharmacokinet· April 2020

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Enterotoxigenic Escherichia coli Heat-Stable Toxin Increases the Rate of Zinc Release from Metallothionein and Is a Zinc- and Iron-Binding Peptide.
Mallory C Kiefer, Natalya I Motyka, John D Clements, Jacob P Bitoun

mSphere· April 2020

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Intradermal or Sublingual Delivery and Heat-Labile Enterotoxin Proteins Shape Immunologic Responses to a CFA/I Fimbria-Derived Subunit Antigen Vaccine against Enterotoxigenic Escherichia coli.
Milton Maciel, David Bauer, Robin L Baudier, Jacob Bitoun, John D Clements

Infect Immun· November 2019

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Exposure-response analysis of blinatumomab in patients with relapsed/refractory acute lymphoblastic leukaemia and comparison with standard of care chemotherapy.
Mita Kuchimanchi, Min Zhu, John D Clements, Sameer Doshi

Br J Clin Pharmacol· April 2019

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Live attenuated enterotoxigenic Escherichia coli (ETEC) vaccine with dmLT adjuvant protects human volunteers against virulent experimental ETEC challenge.
Clayton Harro, A Louis Bourgeois, David Sack, Richard Walker, Barbara DeNearing, John D Clements

Vaccine· March 2019

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Intradermal vaccination with a Pseudomonas aeruginosa vaccine adjuvanted with a mutant bacterial ADP-ribosylating enterotoxin protects against acute pneumonia.
Sarah M Baker, Derek Pociask, John D Clements, James B McLachlan, Lisa A Morici

Vaccine· February 2019

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HIV-1 vaccination by needle-free oral injection induces strong mucosal immunity and protects against SHIV challenge.
Andrew T Jones, Xiaoying Shen, Korey L Walter, Celia C LaBranche, Linda S Wyatt, John D Clements

Nat Commun· February 2019

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Receiver Operating Characteristic Analysis and Clinical Trial Simulation to Inform Dose Titration Decisions.
John David Clements, Juan Jose Perez Ruixo, John P Gibbs, Sameer Doshi, Carlos Perez Ruixo

CPT Pharmacometrics Syst Pharmacol· November 2018

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The Mucosal Vaccine Adjuvant LT(R192G/L211A) or dmLT.
John D Clements, Elizabeth B Norton

mSphere· July 2018

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Transcutaneous Immunization with a Band-Aid Prevents Experimental Otitis Media in a Polymicrobial Model.
Laura A Novotny, John D Clements, Steven D Goodman, Lauren O Bakaletz

Clin Vaccine Immunol· June 2017

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Parenteral Vaccination Can Be an Effective Means of Inducing Protective Mucosal Responses.
John D Clements, Lucy C Freytag

Clin Vaccine Immunol· June 2016

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Evaluating the A-Subunit of the Heat-Labile Toxin (LT) As an Immunogen and a Protective Antigen Against Enterotoxigenic Escherichia coli (ETEC).
Elizabeth B Norton, Luis M Branco, John D Clements

PLoS One· May 2016

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Towards Rational Design of a Toxoid Vaccine against the Heat-Stable Toxin of Escherichia coli.
Arne M Taxt, Yuleima Diaz, Rein Aasland, John D Clements, James P Nataro

Infect Immun· April 2016

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Serum and mucosal antibody responses to inactivated polio vaccine after sublingual immunization using a thermoresponsive gel delivery system.
Jessica A White, Jeremy S Blum, Nancy A Hosken, Joshua O Marshak, Lauren Duncan, John D Clements

Hum Vaccin Immunother· October 2015

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Therapeutic Transcutaneous Immunization with a Band-Aid Vaccine Resolves Experimental Otitis Media.
Laura A Novotny, John D Clements, Lauren O Bakaletz

Clin Vaccine Immunol· August 2015

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The novel adjuvant dmLT promotes dose sparing, mucosal immunity and longevity of antibody responses to the inactivated polio vaccine in a murine model.
Elizabeth B Norton, David L Bauer, William C Weldon, M Steven Oberste, Louise B Lawson, John D Clements

Vaccine· April 2015

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Impact of detergent on biophysical properties and immune response of the IpaDB fusion protein, a candidate subunit vaccine against Shigella species.
Xiaotong Chen, Shyamal P Choudhari, Francisco J Martinez-Becerra, Jae Hyun Kim, Nicholas E Dickenson, John D Clements

Infect Immun· January 2015

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Simultaneous exposure to Escherichia coli heat-labile and heat-stable enterotoxins increases fluid secretion and alters cyclic nucleotide and cytokine production by intestinal epithelial cells.
Lisa T Read, Rachel W Hahn, Carli C Thompson, David L Bauer, Elizabeth B Norton, John D Clements

Infect Immun· December 2014

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Characterization of heat-stable (STa) toxoids of enterotoxigenic Escherichia coli fused to double mutant heat-labile toxin peptide in inducing neutralizing Anti-STa antibodies.
Xiaosai Ruan, Donald C Robertson, James P Nataro, John D Clements, Weiping Zhang

Infect Immun· May 2014

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Evaluation in mice of a conjugate vaccine for cholera made from Vibrio cholerae O1 (Ogawa) O-specific polysaccharide.
Mohammad Murshid Alam, Megan Kelly Bufano, Peng Xu, Anuj Kalsy, Y Yu, John D Clements

PLoS Negl Trop Dis· February 2014

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