Publications by authors named "John D Crispino"

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Loss of Function Mouse Models Reveal a Novel Regulatory Function for ULK1 in Myeloproliferative Neoplasms.
Diana Saleiro, Jeremy Q Wen, Markella Zannikou, Brian Lee, Ewa M Kosciuczuk, John D Crispino

Mol Cell Biol· September 2025

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Meddling with METTL3 in acute megakaryoblastic leukemia.
John D Crispino

Blood· August 2025

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Splicing of erythroid transcription factor is associated with therapeutic response in myelodysplastic syndromes.
Srinivas Aluri, Te Ling, Ellen Fraint, Samarpana Chakraborty, Kevin Zhang, John D Crispino

J Clin Invest· July 2025

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Corrigendum to STAT1 promotes megakaryopoiesis downstream of GATA-1 in mice.
Zan Huang, Terri D Richmond, Andrew G Muntean, Dwayne L Barber, Mitchell J Weiss, John D Crispino

J Clin Invest· July 2025

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Generating Off-the-Shelf Hematopoietic Stem Cells by "Stretching" Induced Pluripotent Stem Cells.
Lei Han, John D Crispino

Am J Hematol· June 2025

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Chromothripsis-associated chromosome 21 amplification orchestrates transformation to blast-phase MPN through targetable overexpression of DYRK1A.
Charlotte K Brierley, Bon Ham Yip, Giulia Orlando, Jeremy Wen, Sean Wen, John D Crispino

Nat Genet· June 2025

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DYRK1A inhibition results in MYC and ERK activation rendering KMT2A-R acute lymphoblastic leukemia cells sensitive to BCL2 inhibition.
V S S Abhinav Ayyadevara, Gerald Wertheim, Shikha Gaur, John A Chukinas, Joseph P Loftus, John D Crispino

Leukemia· May 2025

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Modeling GATA2 deficiency in mice: the R396Q mutation disrupts normal hematopoiesis.
Trent Hall, Rashid Mehmood, Diana Sá da Bandeira, Anitria Cotton, Jonathon Klein, John D Crispino

Leukemia· March 2025

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The developmental clock: where art and science meet.
John D Crispino

Exp Hematol· February 2025

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Disruption of cotranscriptional splicing suggests RBM39 is a therapeutic target in acute lymphoblastic leukemia.
Qi Jin, Ethan Harris, Jacquelyn A Myers, Rashid Mehmood, Anitria Cotton, John D Crispino

Blood· December 2024

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Efficacy of DYRK1A inhibitors in novel models of Down syndrome acute lymphoblastic leukemia.
Shannon L Carey-Smith, Maryam H Simad, Kunjal Panchal, Carlos Aya-Bonilla, Hannah Smolders, John D Crispino

Haematologica· July 2024

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Malignant progression of preleukemic disorders.
Trent Hall, Sandeep Gurbuxani, John D Crispino

Blood· May 2024

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Building Synthetic Biosensors Using Red Blood Cell Proteins.
Taylor B Dolberg, Taylor F Gunnels, Te Ling, Kelly A Sarnese, John D Crispino

ACS Synth Biol· April 2024

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A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia.
Igor Fijalkowski, Jin Wang, Qi Jin, Jolien Van Laere, Valentina Serafin, John D Crispino

Leukemia· January 2024

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Correction: A positive feedback loop regulation between NOTCH1 and USP11 in T-cell leukemia.
Igor Fijalkowski, Jin Wang, Qi Jin, Jolien Van Laere, Valentina Serafin, John D Crispino

Leukemia· January 2024

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Building synthetic biosensors using red blood cell proteins.
Taylor B Dolberg, Taylor F Gunnels, Te Ling, Kelly A Sarnese, John D Crispino

bioRxiv· December 2023

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Introduction to a review series on hematopoietic stem cells.
John D Crispino

Blood· August 2023

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Gata1s mutant mice display persistent defects in the erythroid lineage.
Te Ling, Kevin Zhang, Jiayue Yang, Sandeep Gurbuxani, John D Crispino

Blood Adv· July 2023

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B cell class switch recombination is regulated by DYRK1A through MSH6 phosphorylation.
Liat Stoler-Barak, Ethan Harris, Ayelet Peres, Hadas Hezroni, Mirela Kuka, John D Crispino

Nat Commun· March 2023

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Bone Marrow Avatars: Mimicking Hematopoiesis in a Dish.
Marta Derecka, John D Crispino

Cancer Discov· February 2023

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CALR goes rogue.
Johanna Melo-Cardenas, John D Crispino

Blood· February 2023

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IL-13/IL-4 signaling contributes to fibrotic progression of the myeloproliferative neoplasms.
Johanna Melo-Cardenas, Lavanya Bezavada, Jeremy Chase Crawford, Sandeep Gurbuxani, Anitria Cotton, John D Crispino

Blood· December 2022

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Oncogenic deubiquitination controls tyrosine kinase signaling and therapy response in acute lymphoblastic leukemia.
Qi Jin, Blanca Gutierrez Diaz, Tim Pieters, Yalu Zhou, Sonali Narang, John D Crispino

Sci Adv· December 2022

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PU.1-c-Jun interaction is crucial for PU.1 function in myeloid development.
Xinhui Zhao, Boris Bartholdy, Yukiya Yamamoto, Erica K Evans, Meritxell Alberich-Jordà, John D Crispino

Commun Biol· September 2022

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Discovery of a signaling feedback circuit that defines interferon responses in myeloproliferative neoplasms.
Diana Saleiro, Jeremy Q Wen, Ewa M Kosciuczuk, Frank Eckerdt, Elspeth M Beauchamp, John D Crispino

Nat Commun· April 2022

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