Publications by authors named "John D Gordan"

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Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update.
John D Gordan, Erin B Kennedy, Ghassan K Abou-Alfa, Eliza Beal, Richard S Finn, Terence P Gade, Laura Goff, Shilpi Gupta, Jennifer Guy, Hang T Hoang

May 2024

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Exploration of a Class of Aryl Imidazolyl Ureas As Potent Acid Ceramidase Inhibitors for the Treatment of Fibrotic Diseases.
Richard Beresis, Vijaya Prathigudupu, Carson Cable, Amy Yu, Marc Adler, John D Gordan

ACS Omega· August 2025

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The immortality mechanism of TERT promoter mutant cancers is self-reinforcing and reversible.
Nicholas O Stevers, Somang Kim, Jimmy Bo Yuan, Carter J Barger, Chibo Hong, John D Gordan

Mol Cell· June 2025

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Correction: DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming.
Ilaria Gritti, Jinkai Wan, Vajira Weeresekara, Joel M Vaz, Giuseppe Tarantino, John D Gordan

Cancer Discov· April 2025

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Neratinib Alone or in Combination with Immune Checkpoint Inhibitors with or without Mammalian Target of Rapamycin Inhibitors in Patients with Fibrolamellar Carcinoma.
Ghassan K Abou-Alfa, Tim Meyer, Richard Kinh Gian Do, Sarina A Piha-Paul, Joseph S Light, John D Gordan

Liver Cancer· March 2025

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DNAJB1-PRKACA Fusion Drives Fibrolamellar Liver Cancer through Impaired SIK Signaling and CRTC2/p300-Mediated Transcriptional Reprogramming.
Ilaria Gritti, Jinkai Wan, Vajira Weeresekara, Joel M Vaz, Giuseppe Tarantino, John D Gordan

Cancer Discov· February 2025

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HBV Remodels PP2A Complexes to Rewire Kinase Signaling in Hepatocellular Carcinoma.
Rigney E Turnham, Adriana Pitea, Gwendolyn M Jang, Zhong Xu, Huat Chye Lim, John D Gordan

Cancer Res· February 2025

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Cataracts Associated With Fibroblast Growth Factor Receptor Inhibitors for Cholangiocarcinoma.
Isabell Kassaye, Adam Alyafaie, Karen Zhang, Jacob Lifton, John D Gordan

JAMA Ophthalmol· December 2024

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Protein kinase A and local signaling in cancer.
Kacey J Rosenthal, John D Gordan, John D Scott

Biochem J· November 2024

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Changes in alpha-fetoprotein across the systemic therapy continuum in advanced hepatocellular carcinoma-a real-world, multicenter study.
Michael Li, Lindsay M Hannan, Lipika Goyal, Andrea G Bocobo, Anna L Parks, John D Gordan

Ther Adv Med Oncol· November 2024

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Emerging Therapies for the Management of Human Epidermal Growth Factor Receptor 2-/-Altered Advanced Biliary Tract Cancers.
Emily L Zeme, Katherine Van Loon, Robin K Kelley, John D Gordan

J Clin Oncol· September 2024

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Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights.
Michal G Rose, Erin B Kennedy, Ghassan K Abou-Alfa, Richard S Finn, Terence Gade, John D Gordan

JCO Oncol Pract· August 2024

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DNAJB1-PRKACA fusion protein-regulated LINC00473 promotes tumor growth and alters mitochondrial fitness in fibrolamellar carcinoma.
Rosanna K Ma, Pei-Yin Tsai, Alaa R Farghli, Alexandria Shumway, Matt Kanke, John D Gordan

PLoS Genet· March 2024

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Recruitment of BAG2 to DNAJ-PKAc scaffolds promotes cell survival and resistance to drug-induced apoptosis in fibrolamellar carcinoma.
Sophia M Lauer, Mitchell H Omar, Martin G Golkowski, Heidi L Kenerson, Kyung-Soon Lee, John D Gordan

Cell Rep· February 2024

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New Opportunities to Individualize Frontline Therapy in Advanced Stages of Hepatocellular Carcinoma.
John D Gordan, Bridget P Keenan, Huat Chye Lim, Mark Yarchoan, R Katie Kelley

Drugs· August 2023

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Defining incidence and complications of fibrolamellar liver cancer through tiered computational analysis of clinical data.
Travis Zack, Kurt P Losert, Samantha M Maisel, Jennifer Wild, Amin Yaqubie, John D Gordan

NPJ Precis Oncol· March 2023

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Oncogenic PKA signaling increases c-MYC protein expression through multiple targetable mechanisms.
Gary K L Chan, Samantha Maisel, Yeonjoo C Hwang, Bryan C Pascual, Rebecca R B Wolber, John D Gordan

Elife· January 2023

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A framework for fibrolamellar carcinoma research and clinical trials.
Timothy A Dinh, Alan F Utria, Kevin C Barry, Rosanna Ma, Ghassan K Abou-Alfa, John D Gordan

Nat Rev Gastroenterol Hepatol· May 2022

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EGFR Inhibition Potentiates FGFR Inhibitor Therapy and Overcomes Resistance in FGFR2 Fusion-Positive Cholangiocarcinoma.
Qibiao Wu, Yuanli Zhen, Lei Shi, Phuong Vu, Patricia Greninger, John D Gordan

Cancer Discov· May 2022

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Methods to assess small molecule allosteric modulators of the STRAD pseudokinase.
Tingting Qing, Jin Liu, Fen Liu, Dom C Mitchell, Richard T Beresis, John D Gordan

Methods Enzymol· May 2022

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Targeting a splicing-mediated drug resistance mechanism in prostate cancer by inhibiting transcriptional regulation by PKCβ1.
James E Melnyk, Veronica Steri, Hao G Nguyen, Y Christina Hwang, John D Gordan

Oncogene· March 2022

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Phase II Trial of the Combination of Temsirolimus and Sorafenib in Advanced Hepatocellular Carcinoma with Tumor Mutation Profiling.
Robin K Kelley, Nancy M Joseph, Halla S Nimeiri, Jimmy Hwang, Laura M Kulik, John D Gordan

Liver Cancer· November 2021

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A protein interaction landscape of breast cancer.
Minkyu Kim, Jisoo Park, Mehdi Bouhaddou, Kyumin Kim, Ajda Rojc, John D Gordan

Science· October 2021

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Tumor hepatitis B virus RNA identifies a clinically and molecularly distinct subset of hepatocellular carcinoma.
Huat Chye Lim, John D Gordan

PLoS Comput Biol· February 2021

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Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline.
John D Gordan, Erin B Kennedy, Ghassan K Abou-Alfa, Muhammad Shaalan Beg, Steven T Brower

J Clin Oncol· December 2020

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