May 2024 PMID 38502889

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update.

John D Gordan, Erin B Kennedy, Ghassan K Abou-Alfa, Eliza Beal, Richard S Finn, Terence P Gade, Laura Goff, Shilpi Gupta, Jennifer Guy, Hang T Hoang, Renuka Iyer, Ishmael Jaiyesimi, Minaxi Jhawer, Asha Karippot, Ahmed O Kaseb

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Mentions

Peak: 59 in Mar 2024

across 3 sources since Mar 2024

Extended reach

244,181

potential audience

Total likes

162

Video views

170

Mentions per month

Mar 2024 – Jul 2025

Where it's discussed

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News5 articles
YouTube2 videos

AI synopsis

What people are saying

The discussions prominently highlight the key changes in the ASCO guidelines, with several users expressing excitement at the introduction of new treatment combinations like atezolizumab plus bevacizumab. Phrasing such as 'timely update' and 'must-read for practitioners' conveys both enthusiasm and urgency, reinforcing a shared belief that these guidelines will be pivotal in shaping future treatment directions.

AgreementModerate agreement

The majority of discussions show a supportive attitude toward the ASCO guideline update, particularly in how it informs treatment options.

InterestHigh interest

There is a high level of interest signified by phrases like 'timely update' and clearly voiced inquiries about recent findings.

EngagementModerate engagement

While most posts share similar information, the depth of engagement is moderate as some users include additional insights or links to further readings.

ImpactHigh impact

Many comments indicate a belief that this guideline update will significantly influence treatment strategies for advanced hepatocellular carcinoma.

Abstract in brief

ASCO updated its 2020 guidelines for systemic therapy in patients with advanced hepatocellular carcinoma (HCC), including new evidence from ten randomized controlled trials up to October 2023.
Firstline treatment options now include atezolizumab plus bevacizumab or durvalumab plus tremelimumab for eligible patients, with alternatives like sorafenib or lenvatinib when there are contraindications.
Secondline and thirdline therapy options vary based on prior treatments and patient conditions, with several targeted therapy options available for those who meet specific criteria.

Read the full abstract

All mentions

Updated ASCO Guidelines for Treating Advanced Hepatocellular Carcinoma

Dr. John Gordan discusses the latest ASCO guideline update on systemic therapy for advanced hepatocellular carcinoma (HCC). The new first-line options include atezolizumab with bevacizumab, or durvalumab with…

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土屋淳紀

@Mishima_Fuji · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Jul 27, 2025 · 54 shares · 7 followers View post →

김정한 Jeong Han Kim

@DrJHK · X

RT @hccconnectinfo: ⚠️ New @ASCO guidelines on systemic therapy for advanced #HCC

Aug 20, 2024 · 1 share · 2,312 followers View post →

HCC CONNECT

@hccconnectinfo · X

⚠️ New @ASCO guidelines on systemic therapy for advanced #HCC

Aug 20, 2024 · 2 likes · 1 share · 1,612 followers View post →

Isaura R. Penin

@irodriguezpenin · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights | JCO Oncology Practice https://t.co/HeBqks2lDU

Aug 16, 2024 · 4 likes · 625 followers View post →

Syadwa

@Syadwa85 · X

RT @hccconnectinfo: ⚠️ New @ASCO guideline update on systemic therapy for advanced #HCC!

Aug 4, 2024 · 2 shares · 60 followers View post →

김정한 Jeong Han Kim

@DrJHK · X

RT @hccconnectinfo: ⚠️ New @ASCO guideline update on systemic therapy for advanced #HCC!

Aug 4, 2024 · 2 shares · 2,312 followers View post →

HCC CONNECT

@hccconnectinfo · X

⚠️ New @ASCO guideline update on systemic therapy for advanced #HCC!

Aug 4, 2024 · 1 like · 2 shares · 1,612 followers View post →

Hear2Care

@Hear2CareAll · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights | JCO Oncology Practice https://t.co/nHoXAuTNba

May 28, 2024 · 88 followers View post →

Shafia Rahman

@shafiarahman_ · X

New ASCO HCC guidelines, timely update!! https://t.co/BjwRuwSrl6

May 7, 2024 · 3 likes · 577 followers View post →

HCC CONNECT

@hccconnectinfo · X

Have you read the recent @GlobalLiver article on liver cancer? Including: ✅ Early onset cancer rates are increasing globally ✅ Systemic therapy for advanced hepatocellular carcinoma: ASCO guideline update Read here

May 3, 2024 · 1 like · 1,612 followers View post →

Cancer Library VCC

@VCCLibrary · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights https://t.co/FWS3jBpPTS #Cancer

May 3, 2024 · 1,279 followers View post →

Manolo Veiga #sentidiño #Ferrolmola

@manolo_veiga · X

RT @irodriguezpenin: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights | JCO Oncology Practic…

May 2, 2024 · 1 share · 1,195 followers View post →

Isaura R. Penin

@irodriguezpenin · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update Clinical Insights | JCO Oncology Practice https://t.co/JZawIsczOR

May 2, 2024 · 4 likes · 1 share · 625 followers View post →

Marcelo Ceron ◤✠◢

@marceloceronMD · X

RT @MOCBrasil: Atualização Diretrizes ASCO 2024: Tratamento Sistêmico para Carcinoma Hepatocelular Avançado Confira o texto completo em: h…

Apr 24, 2024 · 2 shares · 1,089 followers View post →

Ricardo Carvalho

@rcarvalhoonco · X

RT @MOCBrasil: Atualização Diretrizes ASCO 2024: Tratamento Sistêmico para Carcinoma Hepatocelular Avançado Confira o texto completo em: h…

Apr 24, 2024 · 2 shares · 2,269 followers View post →

MOC Brasil

@MOCBrasil · X

Apr 24, 2024 · 3 likes · 2 shares · 2,381 followers View post →

Ricardo Carvalho

@rcarvalhoonco · X

RT @dralanburguete: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t.…

Mar 29, 2024 · 1 share · 2,269 followers View post →

Aisling Barry

@aislingbarryro · X

RT @irodriguezpenin: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t…

Mar 28, 2024 · 4 shares · 803 followers View post →

YK10

@oEQ2B2sPOm6G58d · X

進行肝細胞癌ASCOガイドラインupdate. 1st: Atezo+Bev or Durva+Treme 2nd: TKI (e.g., sorafenib, lenvatinib, cabozantinib) or ramucirumab 3rd: 1st, 2ndと違う作用機序のレジメン Child B: cautious approach https://t.co/aqUlrje9w2

Mar 27, 2024 · 27 followers View post →

Mairead G McNamara

@MGMcNamara · X

RT @irodriguezpenin: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t…

Mar 27, 2024 · 4 shares · 378 followers View post →

Conchi Guindel

@CGuindel · X

RT @irodriguezpenin: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t…

Mar 27, 2024 · 4 shares · 359 followers View post →

Rocio asensi

@rocioasensi · X

https://t.co/k1c4RfGuI0

Mar 27, 2024 · 502 followers View post →

Nieves Martinez Lago MD PhD

@DraMartinezLago · X

RT @irodriguezpenin: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t…

Mar 27, 2024 · 4 shares · 2,312 followers View post →

Isaura R. Penin

@irodriguezpenin · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t.co/lhiIS6aXyz

Mar 27, 2024 · 9 likes · 4 shares · 625 followers View post →

ESTRELLA Maria Rita MARTINEZ MD

@ESTRELLAMariaR4 · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t.co/RBDW7Moc1q

Mar 25, 2024 · 863 followers View post →

GIGuidelines

@GiGuidelines · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 24, 2024 · 54 shares · 149 followers View post →

AAyoubi

@AlayoubiAlia · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 24, 2024 · 54 shares · 136 followers View post →

Cancer Library VCC

@VCCLibrary · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/E9tILIhFjG #Cancer

Mar 22, 2024 · 1,279 followers View post →

henryvargas

@henryva08402477 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 21, 2024 · 54 shares · 36 followers View post →

Ippokratis Korantzis, Medical Oncologist, MD, PhD

@newsincancer · X

Systemic Therapy for Advanced #HepatocellularCarcinoma: #ASCOGuideline Update https://t.co/U1dLJ9omme

Mar 21, 2024 · 285 followers View post →

Ingrid Trifan

@ingrid_trifan · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 21, 2024 · 54 shares · 20 followers View post →

Lisardo Ugidos

@OncoUgi · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 21, 2024 · 54 shares · 949 followers View post →

Alejandro Rosales

@HpbNicaragua · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 1,329 followers View post →

Stefan Zilli

@stefan_zilli · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 84 followers View post →

Kyaw Zin Thein, MD

@kyawzinthein86 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 828 followers View post →

Hyemin Huh

@Hyemin_Analyst · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 47 followers View post →

Conchi Guindel

@CGuindel · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 359 followers View post →

Sergio Casillas

@scasillasmd · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 105 followers View post →

viktoria valera

@salingpusalang · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 788 followers View post →

Чиж

@rough_fiddle · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 9 followers View post →

Dr.M Khan

@DrManzoorKhan1 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 586 followers View post →

Umut. Dişel

@UmutDisel · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 20, 2024 · 54 shares · 1,276 followers View post →

whyes

@whyeszhu · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 23,273 followers View post →

Luis Arturo Cardoso Aparicio

@lacamustang · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 271 followers View post →

Alan Burguete-Torres M.D.

@dralanburguete · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update | Journal of Clinical Oncology https://t.co/u9A9w4WAPY

Mar 19, 2024 · 1 like · 1 share · 1,536 followers View post →

Erman Akkus

@Erman_Akkus · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 5,211 followers View post →

Dr. Andrés Neira

@mandresneiraf · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 56 followers View post →

Dawood Findakly, MD, FACP

@dawood_findakly · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 1,240 followers View post →

Roberto Reyna

@rabertreynag · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 31 followers View post →

Ricardo Bruges Maya

@BrugesMaya · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 409 followers View post →

Chris

@ChrisCC92 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 229 followers View post →

Ricardo Carvalho

@rcarvalhoonco · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 2,269 followers View post →

Mridul Khanna

@mridulkhanna91 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 592 followers View post →

Randy Vladimir Hernández Antonio

@randy_vladimir · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 48 followers View post →

Hafiz Hamdi

@HafizHamdi13 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 727 followers View post →

TYR Kinase papers

@tyrkinasepapers · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/klotFis37g

Mar 19, 2024 · 40 followers View post →

ขอฝันใฝ่ในฝันอันเหลือเชื่อ

@Chu0025 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 1,130 followers View post →

Sr Osler

@AlejoZabalet · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 65 followers View post →

ASCO

@ASCO · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 149,471 followers View post →

Diego Soriano

@d_sorianop · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 148 followers View post →

Andrea Zuluaga

@AndreaZuluagaL · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 103 followers View post →

Haycone

@Haycone2 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 57 followers View post →

chargy.om

@AChargy · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 468 followers View post →

Mudoudou

@hugo8720 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 52 followers View post →

Ali Alshehri

@prson55 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 259 followers View post →

Gabrielle F.

@LGabrielleF · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 43 followers View post →

Ramiro J. Tupayachi

@ratupayachi · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 846 followers View post →

Juan F. Arango Arteaga, MD, MSc.

@JuanArango · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 1,111 followers View post →

Angelobcbrito

@angelobcbrito · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 63 followers View post →

CD4+CD25+FoxP3 T-Reg

@boraohanna · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 62 followers View post →

Onur Baş, MD

@onur6191 · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 339 followers View post →

Nieves Martinez Lago MD PhD

@DraMartinezLago · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 2,312 followers View post →

Santhosh Ambika

@RenoHemonc · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 4,005 followers View post →

Alper Topal, MD

@dralpertopal · X

RT @dr_yakupergun: Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6…

Mar 19, 2024 · 54 shares · 499 followers View post →

Yakup Ergün

@dr_yakupergun · X

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update https://t.co/oG93idAbAH https://t.co/t6Wx3Q7cmd

Mar 19, 2024 · 134 likes · 54 shares · 5,837 followers View post →

Systemic Therapy for Advanced Hepatocellular Carcinoma: ASCO Guideline Update.

Mentions per month

Where it's discussed

What people are saying

Abstract in brief

Top posts

All mentions

Updated ASCO Guidelines for Treating Advanced Hepatocellular Carcinoma

Endocrine and Targeted Therapy for HR-Positive, HER2-Negative Metastatic Breast Cancer – Capivase...