Publications by authors named "John D Hayes"

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Far infrared therapy improves vascular function by enhancing endothelial function and decreasing arterial stiffness via cytoprotective pathways.
Hala Bagabir, Omar A Mohammad, Chim C Lang, Albena T Dinkova Kostova, John D Hayes

Free Radic Biol Med· December 2025

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Dual targeting of Keap1 and Gsk-3 by hexaraphane in the regulation of transcription factor Nrf2.
Ángel J García-Yagüe, Eduardo J Cueto-Díaz, Maribel Escoll, Isao Okunishi, John D Hayes

Free Radic Biol Med· November 2025

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The electrophilic metabolite of kynurenine, kynurenine-CKA, targets C151 in Keap1 to derepress Nrf2.
Jialin Feng, Mara Carreño, Hannah Jung, Sharadha Dayalan Naidu, Nicole Arroyo Diaz, John D Hayes

bioRxiv· November 2025

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Genetic Deletion of RHAMM Alleviates Hepatic Oxidative Stress, Reversing Thyroid Stimulating Hormone Elevation in Male Obese Mice.
Tianzhen Wang, Helin Sun, Ayman K Banah, Xiong Weng, Sharadha Dayalan Naidu, John D Hayes

Cells· September 2025

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CD5L is a target of transcription factor Nrf2.
Sharadha Dayalan Naidu, Abel D Ang, Charlotte Lim Jia Yee, Oliver J Read, Tom S Dixon, John D Hayes

Biochem Biophys Res Commun· August 2025

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Health position paper and redox perspectives - Bench to bedside transition for pharmacological regulation of NRF2 in noncommunicable diseases.
Antonio Cuadrado, Eduardo Cazalla, Anders Bach, Boushra Bathish, Sharadha Dayalan Naidu, John D Hayes

Redox Biol· April 2025

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Regulating Nrf2 activity: ubiquitin ligases and signaling molecules in redox homeostasis.
John D Hayes, Sharadha Dayalan Naidu, Albena T Dinkova-Kostova

Trends Biochem Sci· March 2025

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Inhibition of glycogen synthase kinase-3 enhances NRF2 protein stability, nuclear localisation and target gene transcription in pancreatic beta cells.
Chinmai Patibandla, Lidy van Aalten, Albena T Dinkova-Kostova, Tadashi Honda, Antonio Cuadrado, John D Hayes

Redox Biol· May 2024

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Bone marrow involvement by breast implant-associated anaplastic large cell lymphoma.
Wei Du, Oscar Cinco Estalilla, Tomislav Mijo Jelic, John David Hayes, Edward Charles Tobin

Br J Haematol· September 2022

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An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver.
Raquel Fernández-Ginés, José Antonio Encinar, John D Hayes, Baldo Oliva, Maria Isabel Rodríguez-Franco

Redox Biol· September 2022

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Corrigendum to "An inhibitor of interaction between the transcription factor NRF2 and the E3 ubiquitin ligase adapter β-TrCP delivers anti-inflammatory responses in mouse liver" [Redox Biol. 55 (2022) 102396/PMID: 35839629].
Raquel Fernández-Ginés, José Antonio Encinar, John D Hayes, Baldo Oliva, Maria Isabel Rodríguez-Franco

Redox Biol· September 2022

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Nonalcoholic steatohepatitis and mechanisms by which it is ameliorated by activation of the CNC-bZIP transcription factor Nrf2.
Boushra Bathish, Holly Robertson, John F Dillon, Albena T Dinkova-Kostova, John D Hayes

Free Radic Biol Med· August 2022

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Necrotic Granulomatous Inflammation after Use of Small Intestine Submucosa Matrix for Recurrent Compression Neuropathy.
Zachary A Koenig, Jack C Burns, John D Hayes

Plast Reconstr Surg Glob Open· June 2022

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Non-canonical Keap1-independent activation of Nrf2 in astrocytes by mild oxidative stress.
Bashayer R Al-Mubarak, Karen F S Bell, Sudhir Chowdhry, Paul J Meakin, Paul S Baxter, John D Hayes

Redox Biol· November 2021

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Hand Injuries of Coal Miners in Southern West Virginia: A Pilot Study on Health-Care Resources in Southern West Virginia.
Ravi Viradia, Frank H Annie, Maher Kali, Frederic Pollock, John David Hayes

J Emerg Trauma Shock· March 2021

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NRF2 and the Ambiguous Consequences of Its Activation during Initiation and the Subsequent Stages of Tumourigenesis.
Holly Robertson, Albena T Dinkova-Kostova, John D Hayes

Cancers (Basel)· December 2020

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Oxidative Stress in Cancer.
John D Hayes, Albena T Dinkova-Kostova, Kenneth D Tew

Cancer Cell· August 2020

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Induction of the Antioxidant Response by the Transcription Factor NRF2 Increases Bioactivation of the Mutagenic Air Pollutant 3-Nitrobenzanthrone in Human Lung Cells.
Jessica R Murray, Laureano de la Vega, John D Hayes, Ling Duan, Trevor M Penning

Chem Res Toxicol· December 2019

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Farming Related Trauma Injuries in Southern West Virginia With a Focus on Risks, Injury Trends, and Associated Co-morbidities.
Ravi Viradia, Frank H Annie, Maher Kali, John D Hayes, Frederic Pollock

Cureus· October 2019

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Therapeutic targeting of the NRF2 and KEAP1 partnership in chronic diseases.
Antonio Cuadrado, Ana I Rojo, Geoffrey Wells, John D Hayes, Sharon P Cousin

Nat Rev Drug Discov· April 2019

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New insights into nuclear factor erythroid 2-related factors in toxicology and pharmacology.
Jingbo Pi, John D Hayes, Masayuki Yamamoto

Toxicol Appl Pharmacol· March 2019

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Zinc-binding triggers a conformational-switch in the cullin-3 substrate adaptor protein KEAP1 that controls transcription factor NRF2.
Michael McMahon, Samuel R Swift, John D Hayes

Toxicol Appl Pharmacol· December 2018

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Experimental Nonalcoholic Steatohepatitis and Liver Fibrosis Are Ameliorated by Pharmacologic Activation of Nrf2 (NF-E2 p45-Related Factor 2).
Ritu S Sharma, David J Harrison, Dorothy Kisielewski, Diane M Cassidy, Alison D McNeilly, John D Hayes

Cell Mol Gastroenterol Hepatol· March 2018

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A partnership with the proteasome; the destructive nature of GSK3.
Holly Robertson, John D Hayes, Calum Sutherland

Biochem Pharmacol· January 2018

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Oncogene-Stimulated Congestion at the KEAP1 Stress Signaling Hub Allows Bypass of NRF2 and Induction of NRF2-Target Genes that Promote Tumor Survival.
John D Hayes, Albena T Dinkova-Kostova

Cancer Cell· November 2017

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