Publications by authors named "John D Huck"

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Decoy-resistant IL-18 reshapes the tumor microenvironment and enhances rejection by anti-CTLA-4 in renal cell carcinoma.
David A Schoenfeld, Dijana Djureinovic, David G Su, Lin Zhang, Benjamin Y Lu, John D Huck

JCI Insight· November 2024

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The human CD47 checkpoint is targeted by an immunosuppressive salivary factor to enhance arboviral skin infectivity.
Alejandro Marin-Lopez, John D Huck, Allen T Esterly, Veronica Azcutia, Connor Rosen

Sci Immunol· August 2024

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A host-microbiota interactome reveals extensive transkingdom connectivity.
Nicole D Sonnert, Connor E Rosen, Andrew R Ghazi, Eric A Franzosa, Brianna Duncan-Lowey, John D Huck

Nature· April 2024

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IL-18BP mediates the balance between protective and pathological immune responses to Toxoplasma gondii.
Joseph T Clark, Orr-El Weizman, Daniel L Aldridge, Lindsey A Shallberg, Julia Eberhard, John D Huck

Cell Rep· March 2023

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Continuous population-level monitoring of SARS-CoV-2 seroprevalence in a large European metropolitan region.
Marc Emmenegger, Elena De Cecco, David Lamparter, Raphaël P B Jacquat, Julien Riou, John D Huck

iScience· February 2023

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Plasmodium infection is associated with cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein.
Sarah Lapidus, Feimei Liu, Arnau Casanovas-Massana, Yile Dai, John D Huck

Sci Rep· December 2022

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Depletion of exhausted alloreactive T cells enables targeting of stem-like memory T cells to generate tumor-specific immunity.
Simone A Minnie, Olivia G Waltner, Kathleen S Ensbey, Nicole S Nemychenkov, Christine R Schmidt, John D Huck

Sci Immunol· October 2022

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Diverse functional autoantibodies in patients with COVID-19.
Eric Y Wang, Tianyang Mao, Jon Klein, Yile Dai, John D Huck

Nature· July 2021

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infection induces cross-reactive antibodies to carbohydrate epitopes on the SARS-CoV-2 Spike protein.
Sarah Lapidus, Feimei Liu, Arnau Casanovas-Massana, Yile Dai, John D Huck

medRxiv· May 2021

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Diverse Functional Autoantibodies in Patients with COVID-19.
Eric Y Wang, Tianyang Mao, Jon Klein, Yile Dai, John D Huck

medRxiv· February 2021

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Thrombin contributes to cancer immune evasion via proteolysis of platelet-bound GARP to activate LTGF-β.
Alessandra Metelli, Bill X Wu, Brian Riesenberg, Silvia Guglietta, John D Huck

Sci Transl Med· January 2020

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NECA derivatives exploit the paralog-specific properties of the site 3 side pocket of Grp94, the endoplasmic reticulum Hsp90.
John D Huck, Nanette L S Que, Robert M Immormino, Liza Shrestha, Tony Taldone

J Biol Chem· November 2019

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Structures of Hsp90α and Hsp90β bound to a purine-scaffold inhibitor reveal an exploitable residue for drug selectivity.
John D Huck, Nanette L S Que, Sahil Sharma, Tony Taldone, Gabriela Chiosis

Proteins· October 2019

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Structural and Functional Analysis of GRP94 in the Closed State Reveals an Essential Role for the Pre-N Domain and a Potential Client-Binding Site.
John D Huck, Nanette L Que, Feng Hong, Zihai Li, Daniel T Gewirth

Cell Rep· September 2017

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Exploring the Functional Complementation between Grp94 and Hsp90.
Kevin A Maharaj, Nanette L S Que, Feng Hong, John D Huck, Sabrina K Gill

PLoS One· June 2017

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Dynamic DNA binding licenses a repair factor to bypass roadblocks in search of DNA lesions.
Maxwell W Brown, Yoori Kim, Gregory M Williams, John D Huck, Jennifer A Surtees

Nat Commun· February 2016

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