Publications by authors named "John D Rioux"

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Postoperative Ileum Transcriptomics Implicate Sex-Biased Mechanisms in Crohn's Disease Recurrence.
Kyle Gettler, Sini Nagpal, Savannah Washburn, Christopher Tastad, Jiayu Zhang, John D Rioux

Gastroenterology· November 2025

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Serum proteomic and metabolomic analyses from patients with IBD identify biological pathways associated with treatment success with anti-integrin therapy.
John D Rioux, Gabrielle Boucher, Anik Forest, Bertrand Bouchard, Lise Coderre

Immunol Cell Biol· August 2025

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Micronutrients are associated with endoscopic postoperative recurrence in Crohn's disease: a multicenter prospective cohort study in North america.
Michiel T J Bak, Karen Boland, Shadi Nayeri, Krzysztof Borowksi, Pablo A Olivera, John D Rioux

J Crohns Colitis· August 2025

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Disruption of affects B cell development and proliferation in a mouse model of Leigh Syndrome French Canadian type.
Adrien Fois, Sonia Deschênes, Capucine Bourel, Claudine Beauchamp, Félix Lombard-Vadnais, John D Rioux

J Rare Dis (Berlin)· July 2025

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Frequency enrichment of coding variants in a French-Canadian founder population and its implication for inflammatory bowel diseases.
Claude Bhérer, Jean-Christophe Grenier, Justin Pelletier, Gabrielle Boucher, Genevieve Gagnon, John D Rioux

medRxiv· July 2025

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After Surgically Induced Remission, Ileal and Colonic Mucosa-Associated Microbiota Predicts Crohn's Disease Recurrence.
Cristian Hernández-Rocha, Williams Turpin, Krzysztof Borowski, Joanne M Stempak, Ksenija Sabic, John D Rioux

Clin Gastroenterol Hepatol· March 2025

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Inflammatory bowel disease risk gene C1ORF106 regulates actin dynamics in intestinal epithelial cells.
Isabelle Hébert-Milette, Chloé Lévesque, Jean Paquette, Marie-Ève Rivard, Louis Villeneuve, John D Rioux

bioRxiv· March 2025

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Eleven Grand Challenges for Inflammatory Bowel Disease Genetics and Genomics.
Greg Gibson, John D Rioux, Judy H Cho, Talin Haritunians, Akshaya Thoutam

Inflamm Bowel Dis· January 2025

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Improving Reliability of Immunological Assays by Defining Minimal Criteria for Cell Fitness.
Sabine Ivison, Gabrielle Boucher, Grace Zheng, Rosa V Garcia, Rita Kohen, John D Rioux

Immunohorizons· September 2024

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A pilot study to identify blood-based markers associated with response to treatment with Vedolizumab in patients with Inflammatory Bowel Disease.
John D Rioux, Gabrielle Boucher, Anik Forest, Bertrand Bouchard, Lise Coderre

medRxiv· September 2024

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Challenges in IBD Research 2024: Precision Medicine.
Sana Syed, Brigid S Boland, Lauren T Bourke, Lea Ann Chen, Laurie Churchill, John D Rioux

Inflamm Bowel Dis· May 2024

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Clinical Predictors of Early and Late Endoscopic Recurrence Following Ileocolonic Resection in Crohn's Disease.
Cristian Hernández-Rocha, Margaret Walshe, Sondra Birch, Ksenija Sabic, Ujunwa Korie, John D Rioux

J Crohns Colitis· April 2024

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Human induced pluripotent stem cells (hiPSCs) derived cells reflect tissue specificity found in patients with Leigh syndrome French Canadian variant (LSFC).
Roselle Gélinas, Chloé Lévesque, Julie Thompson Legault, Marie-Eve Rivard, Louis Villeneuve, John D Rioux

Front Genet· April 2024

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Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.
Cantin Baron, Sarah Cherkaoui, Sandra Therrien-Laperriere, Yann Ilboudo, Raphaël Poujol, John D Rioux

iScience· December 2023

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Genetic coding variant in complement factor B (CFB) is associated with increased risk for perianal Crohn's disease and leads to impaired CFB cleavage and phagocytosis.
Marzieh Akhlaghpour, Talin Haritunians, Shyam K More, Lisa S Thomas, Dalton T Stamps, John D Rioux

Gut· November 2023

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The role of admixture in the rare variant contribution to inflammatory bowel disease.
Courtney Astore, Shivam Sharma, Sini Nagpal, , David J Cutler, John D Rioux

Genome Med· November 2023

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Serum Lipidomic Screen Identifies Key Metabolites, Pathways, and Disease Classifiers in Crohn's Disease.
Romain Ferru-Clément, Gabrielle Boucher, Anik Forest, Bertrand Bouchard, Alain Bitton, John D Rioux

Inflamm Bowel Dis· July 2023

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Investigating the Crime Scene-Molecular Signatures in Inflammatory Bowel Disease.
Vibeke Andersen, Tue B Bennike, Corinna Bang, John D Rioux, Isabelle Hébert-Milette

Int J Mol Sci· July 2023

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Identifying high-impact variants and genes in exomes of Ashkenazi Jewish inflammatory bowel disease patients.
Yiming Wu, Kyle Gettler, Meltem Ece Kars, Mamta Giri, Dalin Li, John D Rioux

Nat Commun· April 2023

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Gene-metabolite annotation with shortest reactional distance enhances metabolite genome-wide association studies results.
Cantin Baron, Sarah Cherkaoui, Sandra Therrien-Laperriere, Yann Ilboudo, Raphaël Poujol, John D Rioux

bioRxiv· March 2023

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Identifying transcript-level differential expression in primary human immune cells.
Saraï Mola, Claudine Beauchamp, Gabrielle Boucher, Sylvie Lesage, Mohamad Karaky, John D Rioux

Mol Immunol· January 2023

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Large-scale sequencing identifies multiple genes and rare variants associated with Crohn's disease susceptibility.
Aleksejs Sazonovs, Christine R Stevens, Guhan R Venkataraman, Kai Yuan, Brandon Avila, John D Rioux

Nat Genet· September 2022

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Prostaglandins and calprotectin are genetically and functionally linked to the Inflammatory Bowel Diseases.
Mohamad Karaky, Gabrielle Boucher, Saraï Mola, Sylvain Foisy, Claudine Beauchamp, John D Rioux

PLoS Genet· September 2022

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Epigenetic reader SP140 loss of function drives Crohn's disease due to uncontrolled macrophage topoisomerases.
Hajera Amatullah, Isabella Fraschilla, Sreehaas Digumarthi, Julie Huang, Fatemeh Adiliaghdam, John D Rioux

Cell· August 2022

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Human enteric viruses autonomously shape inflammatory bowel disease phenotype through divergent innate immunomodulation.
Fatemeh Adiliaghdam, Hajera Amatullah, Sreehaas Digumarthi, Tahnee L Saunders, Raza-Ur Rahman, John D Rioux

Sci Immunol· April 2022

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