Publications by authors named "John Deighton"

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A Potential Role for Exosomal Translationally Controlled Tumor Protein Export in Vascular Remodeling in Pulmonary Arterial Hypertension.
Elisabet Ferrer, Benjamin J Dunmore, Dhiya Hassan, Mark L Ormiston, Stephen Moore, John Deighton

Am J Respir Cell Mol Biol· October 2018

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TNFα drives pulmonary arterial hypertension by suppressing the BMP type-II receptor and altering NOTCH signalling.
Liam A Hurst, Benjamin J Dunmore, Lu Long, Alexi Crosby, Rafia Al-Lamki, John Deighton

Nat Commun· January 2017

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Assessing the efficacy of oral immunotherapy for the desensitisation of peanut allergy in children (STOP II): a phase 2 randomised controlled trial.
Katherine Anagnostou, Sabita Islam, Yvonne King, Loraine Foley, Laura Pasea, John Deighton

Lancet· April 2014

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BMP type II receptor deficiency confers resistance to growth inhibition by TGF-β in pulmonary artery smooth muscle cells: role of proinflammatory cytokines.
Rachel J Davies, Alan M Holmes, John Deighton, Lu Long, Xudong Yang

Am J Physiol Lung Cell Mol Physiol· March 2012

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Eotaxin-1/CC chemokine ligand 11: a novel eosinophil survival factor secreted by human pulmonary artery endothelial cells.
Neda Farahi, Andrew S Cowburn, Paul D Upton, John Deighton, Anastasia Sobolewski

J Immunol· July 2007

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Aminopeptidase N (CD13) regulates tumor necrosis factor-alpha-induced apoptosis in human neutrophils.
Andrew S Cowburn, Anastasia Sobolewski, Ben J Reed, John Deighton, Joanna Murray

J Biol Chem· May 2006

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z-VAD-fmk augmentation of TNF alpha-stimulated neutrophil apoptosis is compound specific and does not involve the generation of reactive oxygen species.
Andrew S Cowburn, Jessica F White, John Deighton, Sarah R Walmsley, Edwin R Chilvers

Blood· April 2005

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The survival effect of TNF-alpha in human neutrophils is mediated via NF-kappa B-dependent IL-8 release.
Andrew S Cowburn, John Deighton, Sarah R Walmsley, Edwin R Chilvers

Eur J Immunol· June 2004

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Involvement of a ferroprotein sensor in hypoxia-mediated inhibition of neutrophil apoptosis.
Katy I Mecklenburgh, Sarah R Walmsley, Andrew S Cowburn, Michael Wiesener, Benjamin J Reed, John Deighton

Blood· October 2002

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