Publications by authors named "John E Sims"

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Novel protein therapeutic joint retention strategy based on collagen-binding Avimers.
Joanne T Hulme, Warren N D'Souza, Helen J McBride, Bo-Rin Park Yoon, Angela M Willee, John E Sims

J Orthop Res· April 2018

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IL-36 signaling amplifies Th1 responses by enhancing proliferation and Th1 polarization of naive CD4+ T cells.
Solenne Vigne, Gaby Palmer, Praxedis Martin, Céline Lamacchia, Deborah Strebel, John E Sims

Blood· October 2012

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Interleukin-36 (IL-36) ligands require processing for full agonist (IL-36α, IL-36β, and IL-36γ) or antagonist (IL-36Ra) activity.
Jennifer E Towne, Blair R Renshaw, Jason Douangpanya, Brian P Lipsky, Min Shen, John E Sims

J Biol Chem· December 2011

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A novel mutation of IL1RN in the deficiency of interleukin-1 receptor antagonist syndrome: description of two unrelated cases from Brazil.
Adriana A Jesus, Mazen Osman, Clovis A Silva, Peter W Kim, Tuyet-Hang Pham, John E Sims

Arthritis Rheum· December 2011

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Neuron-specific effects of interleukin-1β are mediated by a novel isoform of the IL-1 receptor accessory protein.
Yangyang Huang, Dirk E Smith, Osvaldo Ibáñez-Sandoval, John E Sims, Wilma J Friedman

J Neurosci· December 2011

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IL-36R ligands are potent regulators of dendritic and T cells.
Solenne Vigne, Gaby Palmer, Céline Lamacchia, Praxedis Martin, Dominique Talabot-Ayer, John E Sims

Blood· November 2011

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Interleukin-36-receptor antagonist deficiency and generalized pustular psoriasis.
Slaheddine Marrakchi, Philippe Guigue, Blair R Renshaw, Anne Puel, Xue-Yuan Pei, John E Sims

N Engl J Med· August 2011

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IL-1RL2 and its ligands contribute to the cytokine network in psoriasis.
Hal Blumberg, Huyen Dinh, Charles Dean, Esther S Trueblood, Keith Bailey, John E Sims

J Immunol· October 2010

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Accessory to inflammation.
John E Sims

Nat Immunol· October 2010

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The IL-1 family: regulators of immunity.
John E Sims, Dirk E Smith

Nat Rev Immunol· February 2010

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Externalization of the leaderless cytokine IL-1F6 occurs in response to lipopolysaccharide/ATP activation of transduced bone marrow macrophages.
Unja Martin, John Scholler, Jesse Gurgel, Blair Renshaw, John E Sims

J Immunol· September 2009

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A central nervous system-restricted isoform of the interleukin-1 receptor accessory protein modulates neuronal responses to interleukin-1.
Dirk E Smith, Brian P Lipsky, Chris Russell, Randal R Ketchem, Jacqueline Kirchner, John E Sims

Immunity· June 2009

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Opposing activities of two novel members of the IL-1 ligand family regulate skin inflammation.
Hal Blumberg, Huyen Dinh, Esther S Trueblood, James Pretorius, David Kugler, John E Sims

J Exp Med· October 2007

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Regulation of interleukin-1 activity is enhanced by cooperation between the interleukin-1 receptor type II and interleukin-1 receptor accessory protein.
John E Sims, Dirk E Smith

Eur Cytokine Netw· April 2004

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Interleukin (IL)-1F6, IL-1F8, and IL-1F9 signal through IL-1Rrp2 and IL-1RAcP to activate the pathway leading to NF-kappaB and MAPKs.
Jennifer E Towne, Kirsten E Garka, Blair R Renshaw, G Duke Virca, John E Sims

J Biol Chem· April 2004

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SIGIRR, a negative regulator of Toll-like receptor-interleukin 1 receptor signaling.
David Wald, Jinzhong Qin, Zhendong Zhao, Youcun Qian, Mayumi Naramura, John E Sims

Nat Immunol· September 2003

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Essential pathogenic role of endogenous IL-18 in murine diabetes induced by multiple low doses of streptozotocin. Prevention of hyperglycemia and insulitis by a recombinant IL-18-binding protein: Fc construct.
Ferdinando Nicoletti, Roberto Di Marco, Gianpaolo Papaccio, Ignacio Conget, Ramon Gomis, John E Sims

Eur J Immunol· August 2003

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The soluble form of IL-1 receptor accessory protein enhances the ability of soluble type II IL-1 receptor to inhibit IL-1 action.
Dirk E Smith, Roberta Hanna, Della Friend, Heather Moore, Hongbo Chen, John E Sims

Immunity· January 2003

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A single amino acid difference between human and monkey interleukin (IL)-1beta dictates effective binding to soluble type II IL-1 receptor.
Dirk E Smith, Randal R Ketchem, Heather Moore, Zachary Anderson, Blair R Renshaw, John E Sims

J Biol Chem· December 2002

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Purification, cloning, and characterization of Nek8, a novel NIMA-related kinase, and its candidate substrate Bicd2.
Pamela M Holland, Alison Milne, Kirsten Garka, Richard S Johnson, Cynthia Willis, John E Sims

J Biol Chem· May 2002

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Genomic organization of the interleukin-1 locus.
Scott L Taylor, Blair R Renshaw, Kirsten E Garka, Dirk E Smith, John E Sims

Genomics· May 2002

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IL-1 and IL-18 receptors, and their extended family.
John E Sims

Curr Opin Immunol· February 2002

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