Publications by authors named "John Gerdes"

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First-in-human healthy volunteer dosimetry studies of the excitatory amino acid transporter 2 (EAAT2) PET imaging tracer methyl N-(7-[F]fluoro-9H-fluoren-2-yl)asparaginate, [F]RP-115.
Chih-Kai Chao, Joseph Blecha, Ilona Polvoy, Ryan Michael Nillo, Youngho Seo, John M Gerdes

Nucl Med Biol· May 2025

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The Design and Evaluation of a Simulation Tool for Audiology Screening Education: Design Science Approach.
John Gerdes, Benjamin Schooley, Dakota Sharp, Juliana Miller

JMIR Form Res· February 2025

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Distribution of insulin in primate brain following nose-to-brain transport.
Kylie Smith, Jinda Fan, Gwendolyn A Marriner, John Gerdes, Robert Kessler

Alzheimers Dement (N Y)· March 2024

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[C]Paraoxon: Radiosynthesis, Biodistribution and In Vivo Positron Emission Tomography Imaging in Rat.
Thomas R Hayes, Chih-Kai Chao, Joseph E Blecha, Tony L Huynh, Henry F VanBrocklin, John M Gerdes

J Pharmacol Exp Ther· January 2024

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Targeting Chikungunya Virus Replication by Benzoannulene Inhibitors.
S Kaleem Ahmed, Nicole N Haese, Jaden T Cowan, Vibha Pathak, Omar Moukha-Chafiq, John M Gerdes

J Med Chem· April 2021

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Inhibition of the Vesicular Glutamate Transporter (VGLUT) with Congo Red Analogs: New Binding Insights.
David M Hitt, Jeffery D Zwicker, Chih-Kai Chao, Sarjubhai A Patel, John M Gerdes

Neurochem Res· March 2021

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Biological Distribution and Metabolic Profiles of Carbon-11 and Fluorine-18 Tracers of VX- and Sarin-Analogs in Sprague-Dawley Rats.
Thomas R Hayes, Chih-Kai Chao, Joseph E Blecha, Tony L Huynh, Kurt R Zinn, John M Gerdes

Chem Res Toxicol· January 2021

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Positron emission tomography evaluation of oxime countermeasures in live rats using the tracer O-(2-[ F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate [ F]-VXS.
Thomas R Hayes, Joseph E Blecha, Chih-Kai Chao, Tony L Huynh, Henry F VanBrocklin, John M Gerdes

Ann N Y Acad Sci· November 2020

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Positron emission tomography studies of organophosphate chemical threats and oxime countermeasures.
Charles M Thompson, John M Gerdes, Henry F VanBrocklin

Neurobiol Dis· January 2020

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Divergent synthesis of organophosphate [C]VX- and [C]Sarin-surrogates from a common set of starting materials.
Thomas R Hayes, Joseph E Blecha, Charles M Thompson, John M Gerdes, Henry F VanBrocklin

Appl Radiat Isot· September 2019

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Radiosynthesis, ex Vivo Biodistribution, and in Vivo Positron Emission Tomography Imaging Evaluations of [C]2-Pyridinealdoxime Methiodide ([C]2-PAM): A First-In-Class Antidote Tracer for Organophosphate Intoxication.
Kiel D Neumann, Joseph E Blecha, Thomas R Hayes, Tony Huynh, Chih-Kai Chao, John M Gerdes

ACS Chem Neurosci· December 2018

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Radiosynthesis of O-(1-[ F]fluoropropan-2-yl)-O-(4-nitrophenyl)methylphosphonate: A novel PET tracer surrogate of sarin.
Thomas R Hayes, Charles M Thompson, Joseph E Blecha, John M Gerdes, Henry F VanBrocklin

J Labelled Comp Radiopharm· December 2018

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The inhibition, reactivation and mechanism of VX-, sarin-, fluoro-VX and fluoro-sarin surrogates following their interaction with HuAChE and HuBuChE.
Chih-Kai Chao, Narayanaganesh Balasubramanian, John M Gerdes, Charles M Thompson

Chem Biol Interact· August 2018

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An improved radiosynthesis of O-(2-[ F]fluoroethyl)-O-(p-nitrophenyl)methylphosphonate: A first-in-class cholinesterase PET tracer.
Kiel D Neumann, Charles M Thompson, Joseph E Blecha, John M Gerdes, Henry F VanBrocklin

J Labelled Comp Radiopharm· June 2017

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Novel Organophosphate Ligand O-(2-Fluoroethyl)-O-(p-Nitrophenyl)Methylphosphonate: Synthesis, Hydrolytic Stability and Analysis of the Inhibition and Reactivation of Cholinesterases.
Chih-Kai Chao, S Kaleem Ahmed, John M Gerdes, Charles M Thompson

Chem Res Toxicol· November 2016

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IMPROVING INDIVIDUAL PROVIDER PATIENT SATISFACTION SCORES IN CARDIOLOGY.
E Randall Hutchison, Peter Berger, Jeffrey Tiesi, Robert Spahr, John Gerdes

Physician Leadersh J· December 2015

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A novel fluorine-18 β-fluoroethoxy organophosphate positron emission tomography imaging tracer targeted to central nervous system acetylcholinesterase.
Shelly L James, S Kaleem Ahmed, Stephanie Murphy, Michael R Braden, Yamina Belabassi, John M Gerdes

ACS Chem Neurosci· July 2014

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The development of benzo- and naphtho-fused quinoline-2,4-dicarboxylic acids as vesicular glutamate transporter (VGLUT) inhibitors reveals a possible role for neuroactive steroids.
Christina N Carrigan, Sarjubhai A Patel, Holly D Cox, Erin S Bolstad, John M Gerdes

Bioorg Med Chem Lett· February 2014

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Synthesis and anti-acetylcholinesterase properties of novel β- and γ-substituted alkoxy organophosphonates.
S Kaleem Ahmed, Yamina Belabassi, Lakshmi Sankaranarayanan, Chih-Kai Chao, John M Gerdes

Bioorg Med Chem Lett· April 2013

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Development of effective PET and SPECT imaging agents for the serotonin transporter: has a twenty-year journey reached its destination?
Yiyun Huang, Ming-Qiang Zheng, John M Gerdes

Curr Top Med Chem· February 2011

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Inhibition of acetylcholinesterase by chromophore-linked fluorophosphonates.
Lilu Guo, Alirica I Suarez, Michael R Braden, John M Gerdes, Charles M Thompson

Bioorg Med Chem Lett· February 2010

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Patient satisfaction and physician productivity: complementary or mutually exclusive?
G Craig Wood, Robert Spahr, John Gerdes, Zahra S Daar, Randall Hutchison

Am J Med Qual· January 2010

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Isoxazole analogues bind the system xc- transporter: structure-activity relationship and pharmacophore model.
Sarjubhai A Patel, Trideep Rajale, Erin O'Brien, David J Burkhart, Jared K Nelson, John M Gerdes

Bioorg Med Chem· January 2010

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Point-of-care diagnostics for global health.
Paul Yager, Gonzalo J Domingo, John Gerdes

Annu Rev Biomed Eng· October 2008

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Lavendamycin antitumor agents: structure-based design, synthesis, and NAD(P)H:quinone oxidoreductase 1 (NQO1) model validation with molecular docking and biological studies.
Mary Hassani, Wen Cai, Katherine H Koelsch, David C Holley, Anthony S Rose, John M Gerdes

J Med Chem· June 2008

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