Publications by authors named "John Gitonga"

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Comparative performance of the InBios SCoV-2 Detect IgG ELISA and the in-house KWTRP ELISA in detecting SARS-CoV-2 spike IgG antibodies in Kenyan populations.
Bernadette Kutima, Eunice Wageci Kagucia, Kennedy Mwai, Makobu Kimani, Antipa Sigilai, John N Gitonga

Wellcome Open Res· September 2025

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Assessing the Impact of SARS-CoV-2 Spike Mutations on Antibody Binding: A Comparative Assessment of the Wuhan and JN.1 Variants' Full-Length Spikes in a Multiplex Luminex Assay.
Gerald Waweru, Ruth Nyakundi, Bernadette Kutima, Sharon Owuor, Gloria Konyino, John Gitonga

Viruses· September 2025

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Age differences in immunity to human seasonal coronaviruses and the immunogenicity of ChAdOx1 nCoV-19 (AZD1222).
Sandra Belij-Rammerstorfer, Emma Sheehan, Grace Li, Sagida Bibi, Daniel Wright, John N Gitonga

EBioMedicine· August 2025

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Meeting report: CEPI workshop on Rift Valley fever epidemiology and modeling to inform human vaccine development, Nairobi, 4-5 June 2024.
Radhika Gharpure, Carolin Vegvari, Alemseged Abdissa, Yewande Alimi, Assaf Anyamba, John Gitonga

Vaccine· April 2025

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Low-Dose Yellow Fever Vaccine in Adults in Africa.
Derick Kimathi, Aitana Juan-Giner, Ndeye S Bob, Benedict Orindi, Maria L Namulwana, John N Gitonga

N Engl J Med· February 2025

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Kinetics of naturally induced binding and neutralising anti-SARS-CoV-2 antibody levels and potencies among SARS-CoV-2 infected Kenyans with diverse grades of COVID-19 severity: an observational study.
John Kimotho, Yiakon Sein, Shahin Sayed, Reena Shah, Kennedy Mwai, John N Gitonga

Wellcome Open Res· December 2024

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Evaluation of population immunity against SARS-CoV-2 variants, EG.5.1, FY.4, BA.2.86, JN.1, JN.1.4, and KP.3.1.1 using samples from two health demographic surveillance systems in Kenya.
Doreen Lugano, Bernadette Kutima, Makobu Kimani, Antipa Sigilai, John Gitonga

BMC Infect Dis· December 2024

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Safety and immunogenicity of ChAdOx1 nCoV-19 (AZD1222) vaccine in adults in Kenya: a phase 1/2 single-blind, randomised controlled trial.
Mainga Hamaluba, Samuel Sang, Benedict Orindi, Irene Njau, Henry Karanja, John N Gitonga

Wellcome Open Res· November 2023

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SARS-CoV-2 seroprevalence and implications for population immunity: Evidence from two Health and Demographic Surveillance System sites in Kenya, February-December 2022.
E Wangeci Kagucia, Abdhala K Ziraba, James Nyagwange, Bernadette Kutima, Makobu Kimani, John Gitonga

Influenza Other Respir Viruses· September 2023

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Safety and immunogenicity of a ChAdOx1 vaccine against Rift Valley fever in UK adults: an open-label, non-randomised, first-in-human phase 1 clinical trial.
Daniel Jenkin, Daniel Wright, Pedro M Folegatti, Abigail Platt, Ian Poulton, John N Gitonga

Lancet Infect Dis· August 2023

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Immunogenicity and safety of fractional doses of 17D-213 yellow fever vaccine in HIV-infected people in Kenya (YEFE): a randomised, double-blind, non-inferiority substudy of a phase 4 trial.
Derick Kimathi, Aitana Juan-Giner, Benedict Orindi, Kyra H Grantz, Ndeye S Bob, John Gitonga

Lancet Infect Dis· August 2023

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Serum immunoglobulin G and mucosal immunoglobulin A antibodies from prepandemic samples collected in Kilifi, Kenya, neutralize SARS-CoV-2 in vitro.
James Nyagwange, Bernadette Kutima, Kennedy Mwai, Henry K Karanja, John N Gitonga

Int J Infect Dis· February 2023

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Validation of saline, PBS and a locally produced VTM at varying storage conditions to detect the SARS-CoV-2 virus by qRT-PCR.
Caroline Ngetsa, Victor Osoti, Dorcas Okanda, Faith Marura, Krupali Shah, John Gitonga

PLoS One· February 2023

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Sero-surveillance for IgG to SARS-CoV-2 at antenatal care clinics in three Kenyan referral hospitals: Repeated cross-sectional surveys 2020-21.
Ruth K Lucinde, Daisy Mugo, Christian Bottomley, Angela Karani, Elizabeth Gardiner, John N Gitonga

PLoS One· October 2022

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SARS-CoV-2 seroprevalence in three Kenyan health and demographic surveillance sites, December 2020-May 2021.
Anthony O Etyang, Ifedayo Adetifa, Richard Omore, Thomas Misore, Abdhalah K Ziraba, John Gitonga

PLOS Glob Public Health· August 2022

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Incidence of chikungunya virus infections among Kenyan children with neurological disease, 2014-2018: A cohort study.
Doris K Nyamwaya, Mark Otiende, Lilian Mwango, Symon M Kariuki, Berrick Otieno, John N Gitonga

PLoS Med· May 2022

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An optimization of four SARS-CoV-2 qRT-PCR assays in a Kenyan laboratory to support the national COVID-19 rapid response teams.
Khadija Said Mohammed, Zaydah R de Laurent, Donwilliams O Omuoyo, Clement Lewa, Elijah Gicheru, John N Gitonga

Wellcome Open Res· March 2022

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Epidemiology of COVID-19 infections on routine polymerase chain reaction (PCR) and serology testing in Coastal Kenya.
James Nyagwange, Leonard Ndwiga, Kelvin Muteru, Kevin Wamae, James Tuju, John Gitonga

Wellcome Open Res· February 2022

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Seroprevalence of Antibodies to Severe Acute Respiratory Syndrome Coronavirus 2 Among Healthcare Workers in Kenya.
Anthony O Etyang, Ruth Lucinde, Henry Karanja, Catherine Kalu, Daisy Mugo, John Gitonga

Clin Infect Dis· January 2022

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Comparative performance of WANTAI ELISA for total immunoglobulin to receptor binding protein and an ELISA for IgG to spike protein in detecting SARS-CoV-2 antibodies in Kenyan populations.
James Nyagwange, Bernadette Kutima, Kennedy Mwai, Henry K Karanja, John N Gitonga

J Clin Virol· January 2022

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COVID-19 transmission dynamics underlying epidemic waves in Kenya.
Samuel P C Brand, John Ojal, Rabia Aziza, Vincent Were, Emelda A Okiro, John N Gitonga

Science· November 2021

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Anti-Severe Acute Respiratory Syndrome Coronavirus 2 Immunoglobulin G Antibody Seroprevalence Among Truck Drivers and Assistants in Kenya.
E Wangeci Kagucia, John N Gitonga, Catherine Kalu, Eric Ochomo, Benard Ochieng

Open Forum Infect Dis· July 2021

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Temporal trends of SARS-CoV-2 seroprevalence during the first wave of the COVID-19 epidemic in Kenya.
Ifedayo M O Adetifa, Sophie Uyoga, John N Gitonga, Daisy Mugo, Mark Otiende

Nat Commun· June 2021

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Pooled testing conserves SARS-CoV-2 laboratory resources and improves test turn-around time: experience on the Kenyan Coast.
Charles N Agoti, Martin Mutunga, Arnold W Lambisia, Domtila Kimani, Robinson Cheruiyot, John N Gitonga

Wellcome Open Res· February 2021

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Endemic chikungunya fever in Kenyan children: a prospective cohort study.
Doris K Nyamwaya, Mark Otiende, Donwilliams O Omuoyo, George Githinji, Henry K Karanja, John N Gitonga

BMC Infect Dis· February 2021

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