Publications by authors named "John Howl"

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Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility.
Joana Vieira Silva, Maria João Freitas, Joana Santiago, Sarah Jones, Sofia Guimarães, Srinivasan Vijayaraghavan, Steven Publicover, Giorgio Colombo, John Howl, Margarida Fardilha

Fertil Steril· February 2021

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Identification of the PP1 interactome in human dental pulp: Insights for regenerative strategies.
Anna Kobrock, Daniela Patrício, Bárbara Matos, Eduardo Zarzuela, Javier Muñoz, John Howl

Cell Signal· December 2025

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Exploring the feasibility of protein phosphatase 1-docking motif-mimetic cell-penetrating peptides for modulating prostate carcinogenesis.
Renato M Rodrigues, Juliana Felgueiras, Sarah Jones, Vânia Camilo, Bárbara Matos, John Howl

JNCI Cancer Spectr· November 2025

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The surface proteome of rabbit spermatozoa.
Patrícia Pinto-Pinho, Francis Impens, Sara Dufour, Delphi Van Haver, Rosário Pinto-Leite, John Howl

Anim Reprod Sci· May 2025

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CAVPENET Peptide Inhibits Prostate Cancer Cells Proliferation and Migration through PP1γ-Dependent Inhibition of AKT Signaling.
Bárbara Matos, Antoniel A S Gomes, Raquel Bernardino, Marco G Alves, John Howl

Pharmaceutics· September 2024

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Enhancing Dental Pulp Stem Cell Proliferation and Odontogenic Differentiation with Protein Phosphatase 1-Disrupting Peptide: An In Vitro Study.
Anna Kobrock, Bárbara Matos, Daniela Patrício, Liliana Grenho, John Howl

Cells· July 2024

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Differential Proteomic Analysis of Human Sperm: A Systematic Review to Identify Candidate Targets to Monitor Sperm Quality.
Pedro O Corda, Jéssica Moreira, John Howl, Pedro F Oliveira, Margarida Fardilha

World J Mens Health· January 2024

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Stem Cell Bioengineering with Bioportides: Inhibition of Planarian Head Regeneration with Peptide Mimetics of Eyes Absent Proteins.
Sarah Jones, Bárbara Matos, Sarah Dennison, Margarida Fardilha, John Howl

Pharmaceutics· July 2023

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Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides: The Genesis of STOPSPERM Bioportides.
John Howl, Joana Vieira Silva, Margarida Fardilha, Sarah Jones

Methods Mol Biol· January 2022

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All you need to know about sperm RNAs.
Joana Santiago, Joana V Silva, John Howl, Manuel A S Santos, Margarida Fardilha

Hum Reprod Update· December 2021

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Modulation of serine/threonine-protein phosphatase 1 (PP1) complexes: A promising approach in cancer treatment.
Bárbara Matos, John Howl, Carmen Jerónimo, Margarida Fardilha

Drug Discov Today· November 2021

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Chronic exercise training attenuates prostate cancer-induced molecular remodelling in the testis.
Bárbara Matos, Daniela Patrício, Magda C Henriques, Maria J Freitas, Rui Vitorino, John Howl

Cell Oncol (Dordr)· April 2021

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The disruption of protein-protein interactions as a therapeutic strategy for prostate cancer.
Bárbara Matos, John Howl, Carmen Jerónimo, Margarida Fardilha

Pharmacol Res· November 2020

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The planarian Schmidtea mediterranea as a model system for the discovery and characterization of cell-penetrating peptides and bioportides.
Sarah Jones, Shaimaa Osman, John Howl

Chem Biol Drug Des· June 2019

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Exploring the effect of exercise training on testicular function.
Bárbara Matos, John Howl, Rita Ferreira, Margarida Fardilha

Eur J Appl Physiol· January 2019

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The cationic tetradecapeptide mastoparan as a privileged structure for drug discovery: Enhanced antimicrobial properties of mitoparan analogues modified at position-14.
John Howl, Lewis Howl, Sarah Jones

Peptides· March 2018

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Modulation of mitochondrial activity in HaCaT keratinocytes by the cell penetrating peptide Z-Gly-RGD(DPhe)-mitoparan.
Adam Richardson, Lewis Muir, Sasha Mousdell, Darren Sexton, Sarah Jones, John Howl

BMC Res Notes· January 2018

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Protein Mimicry and the Design of Bioactive Cell-Penetrating Peptides.
John Howl, Sarah Jones

Methods Mol Biol· April 2016

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Intracellular Target-Specific Accretion of Cell Penetrating Peptides and Bioportides: Ultrastructural and Biological Correlates.
Sarah Jones, Julia Uusna, Ülo Langel, John Howl

Bioconjug Chem· January 2016

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Cell-penetrating peptides, targeting the regulation of store-operated channels, slow decay of the progesterone-induced [Ca2+]i signal in human sperm.
Jennifer Morris, Sarah Jones, John Howl, Monika Lukanowska, Linda Lefievre

Mol Hum Reprod· July 2015

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Cell penetrating peptide-mediated transport enables the regulated secretion of accumulated cargoes from mast cells.
John Howl, Sarah Jones

J Control Release· March 2015

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Insights into the molecular mechanisms of action of bioportides: a strategy to target protein-protein interactions.
John Howl, Sarah Jones

Expert Rev Mol Med· January 2015

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Bioportides: bioactive cell-penetrating peptides that modulate cellular dynamics.
Monika Lukanowska, John Howl, Sarah Jones

Biotechnol J· August 2013

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Can RNAi-mediated hsp90α knockdown in combination with 17-AAG be a therapy for glioma?
Adi Mehta, Amal Shervington, John Howl, Sarah Jones, Leroy Shervington

FEBS Open Bio· August 2013

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Intracellular translocation and differential accumulation of cell-penetrating peptides in bovine spermatozoa: evaluation of efficient delivery vectors that do not compromise human sperm motility.
Sarah Jones, Monika Lukanowska, Julia Suhorutsenko, Senga Oxenham, Christopher Barratt, John Howl

Hum Reprod· July 2013

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