PubHawk
Fertil Steril February 2021 PMID 32977940

Disruption of protein phosphatase 1 complexes with the use of bioportides as a novel approach to target sperm motility.

Joana Vieira Silva, Maria João Freitas, Joana Santiago, Sarah Jones, Sofia Guimarães, Srinivasan Vijayaraghavan, Steven Publicover, Giorgio Colombo, John Howl, Margarida Fardilha

Full text PDF Download social card

Mentions

2
Peak: 1 in Jan 2022
across 2 sources since Jan 2022

Extended reach

270
potential audience

Total likes

5

Video views

153

Mentions per month

Jan 2022 – Mar 2022

Where it's discussed

  • X / Twitter1 posts
  • YouTube1 videos

AI synopsis

What people are saying

The overall tone is neutral, as seen in minimal comments such as sharing a video with hashtags like #Malecontraception and mentioning academic institutions, but without detailed opinions or insights, indicating limited engagement or impact. The language and tone focus more on sharing content rather than critically analyzing or debating the research's significance.

AgreementNeither agree nor disagree

The discussion lacks clear expressions of strong agreement or disagreement with the publication, indicating neutrality or indifference towards the findings.

InterestModerate interest

The mention of hashtags and institutional references suggests a mild interest, but no detailed analysis or strong reactions are present.

EngagementNeutral engagement

The discussion appears superficial, with minimal depth — mainly sharing a video link without extensive commentary or questions.

ImpactNeutral impact

There is no indication that these discussions have a significant impact on opinions or further research, reflecting a neutral stance on the importance of the work.

Abstract in brief

  • Researchers designed peptides that disrupt protein phosphatase 1 (PP1) and coupled them with cell-penetrating peptides (CPPs) to affect sperm motility.
  • The study involved analyzing sperm samples from healthy men and Holstein bulls in a lab setting.
  • The results showed that these bioportides were successfully delivered to sperm cells, significantly reducing sperm motility and providing insights into the role of PP1 in male fertility.
Read the full abstract

Top posts

Most liked on X and Bluesky
Lab for Reproductive Pharmacology & Andrology
@LfraUnesp · X

Here is another video: https://t.co/apXHVYLVs9 #Malecontraception #Science #engagement #COIL #UNESP #UniversityofAveiro

Mar 10, 2022 · 117 followers View post →

All mentions

Lab for Reproductive Pharmacology & Andrology
@LfraUnesp · X

Here is another video: https://t.co/apXHVYLVs9 #Malecontraception #Science #engagement #COIL #UNESP #UniversityofAveiro

Mar 10, 2022 · 117 followers View post →