Publications by authors named "John Luddy"

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A phase I study of the first-in-class antimitochondrial metabolism agent, CPI-613, in patients with advanced hematologic malignancies.
Timothy S Pardee, King Lee, John Luddy, Claudia Maturo, Robert Rodriguez

Clin Cancer Res· October 2014

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Translational assessment of mitochondrial dysfunction of pancreatic cancer from in vitro gene microarray and animal efficacy studies, to early clinical studies, via the novel tumor-specific anti-mitochondrial agent, CPI-613.
King C Lee, Claudia Maturo, Candida N Perera, John Luddy, Robert Rodriguez

Ann Transl Med· September 2014

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Multi-faced neuroprotective effects of Ginsenoside Rg1 in an Alzheimer mouse model.
Fang Fang, Xiaochun Chen, Tianwen Huang, Lih-Fen Lue, John S Luddy

Biochim Biophys Acta· February 2012

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RAGE-dependent signaling in microglia contributes to neuroinflammation, Abeta accumulation, and impaired learning/memory in a mouse model of Alzheimer's disease.
Fang Fang, Lih-Fen Lue, Shiqiang Yan, Hongwei Xu, John S Luddy

FASEB J· April 2010

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ABAD enhances Abeta-induced cell stress via mitochondrial dysfunction.
Kazuhiro Takuma, Jun Yao, Jianmin Huang, Hongwei Xu, Xi Chen, John Luddy

FASEB J· April 2005

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RAGE potentiates Abeta-induced perturbation of neuronal function in transgenic mice.
Ottavio Arancio, Hui Ping Zhang, Xi Chen, Chang Lin, Fabrizio Trinchese, John S Luddy

EMBO J· October 2004

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