Publications by authors named "John Macmaster"

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An antibody to IP-10 is a potent antagonist of cell migration in vitro and in vivo and does not affect disease in several animal models of inflammation.
Fergus R Byrne, Aaron Winters, David Brankow, Sylvia Hu, Todd Juan, John Macmaster

Autoimmunity· March 2009

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Synthesis and biological evaluation of 4-amino derivatives of benzimidazoquinoxaline, benzimidazoquinoline, and benzopyrazoloquinazoline as potent IKK inhibitors.
Francis Beaulieu, Carl Ouellet, Edward H Ruediger, Makonen Belema, Yuping Qiu, John F MacMaster

Bioorg Med Chem Lett· March 2007

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Collagen and aggrecan degradation is blocked in interleukin-1-treated cartilage explants by an inhibitor of IkappaB kinase through suppression of metalloproteinase expression.
Mark A Pattoli, John F MacMaster, Kurt R Gregor, James R Burke

J Pharmacol Exp Ther· October 2005

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BMS-345541 is a highly selective inhibitor of I kappa B kinase that binds at an allosteric site of the enzyme and blocks NF-kappa B-dependent transcription in mice.
James R Burke, Mark A Pattoli, Kurt R Gregor, Patrick J Brassil, John F MacMaster

J Biol Chem· January 2003

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Reductively activated disulfide prodrugs of paclitaxel.
Vivekananda M Vrudhula, John F MacMaster, Zhengong Li, David E Kerr, Peter D Senter

Bioorg Med Chem Lett· December 2002

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Discovery of N-[2-[2-[[3-methoxy-4-(5-oxazolyl)phenyl]amino]-5-oxazolyl]phenyl]-N-methyl-4- morpholineacetamide as a novel and potent inhibitor of inosine monophosphate dehydrogenase with excellent in vivo activity.
T G Murali Dhar, Zhongqi Shen, Junqing Guo, Chunjian Liu, Scott H Watterson, John F MacMaster

J Med Chem· May 2002

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