Publications by authors named "John Means"

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Clinical Long-Read Sequencing Test for Genetic Disease Diagnosis.
Isabelle Thiffault, Emily Farrow, Cassandra Barrett, Meadow Scott, Amy Ross, John C Means

JAMA Pediatr· December 2025

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Rapid and scalable personalized ASO screening in patient-derived organoids.
John C Means, Anabel L Martinez-Bengochea, Daniel A Louiselle, Jacqelyn M Nemechek, John M Perry

Nature· February 2025

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Case of CLPB deficiency solved by HiFi long read genome sequencing and RNAseq.
Emily Farrow, Allison Jay, John Means, Scott Younger, Rebecca Biswell

Am J Med Genet A· December 2023

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Direct haplotype-resolved 5-base HiFi sequencing for genome-wide profiling of hypermethylation outliers in a rare disease cohort.
Warren A Cheung, Adam F Johnson, William J Rowell, Emily Farrow, Richard Hall, John C Means

Nat Commun· May 2023

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Massively parallel identification of functionally consequential noncoding genetic variants in undiagnosed rare disease patients.
Jasmine A McQuerry, Merry Mclaird, Samantha N Hartin, John C Means, Jeffrey Johnston

Sci Rep· May 2022

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A practical guide to teaching with Proteopedia.
Claudia Castro, R Jeremy Johnson, Bruno Kieffer, John A Means, Ann Taylor

Biochem Mol Biol Educ· September 2021

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Estrogen Protects Optic Nerve Head Astrocytes Against Oxidative Stress by Preventing Caspase-3 Activation, Tau Dephosphorylation at Ser and the Formation of Tau Protein Aggregates.
John C Means, Adam A Lopez, Peter Koulen

Cell Mol Neurobiol· April 2021

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Expediting rare disease diagnosis: a call to bridge the gap between clinical and functional genomics.
Samantha N Hartin, John C Means, Joseph T Alaimo, Scott T Younger

Mol Med· November 2020

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Resveratrol Protects Optic Nerve Head Astrocytes from Oxidative Stress-Induced Cell Death by Preventing Caspase-3 Activation, Tau Dephosphorylation at Ser and Formation of Misfolded Protein Aggregates.
John C Means, Adam A Lopez, Peter Koulen

Cell Mol Neurobiol· August 2020

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Distinct Mechanisms Underlying Resveratrol-Mediated Protection from Types of Cellular Stress in C6 Glioma Cells.
John C Means, Bryan C Gerdes, Peter Koulen

Int J Mol Sci· July 2017

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Caspase-3-Dependent Proteolytic Cleavage of Tau Causes Neurofibrillary Tangles and Results in Cognitive Impairment During Normal Aging.
John C Means, Bryan C Gerdes, Simon Kaja, Nathalie Sumien, Andrew J Payne

Neurochem Res· September 2016

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The role of casein kinase I in the Drosophila circadian clock.
Jeffrey L Price, Jin-Yuan Fan, Andrew Keightley, John C Means

Methods Enzymol· October 2015

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Drosophila DBT Autophosphorylation of Its C-Terminal Domain Antagonized by SPAG and Involved in UV-Induced Apoptosis.
Jin-Yuan Fan, John C Means, Edward S Bjes, Jeffrey L Price

Mol Cell Biol· July 2015

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Drosophila spaghetti and doubletime link the circadian clock and light to caspases, apoptosis and tauopathy.
John C Means, Anandakrishnan Venkatesan, Bryan Gerdes, Jin-Yuan Fan, Edward S Bjes

PLoS Genet· May 2015

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Intrahaemocoelic infection of Trichoplusia ni with the baculovirus Autographa californica M nucleopolyhedrovirus does not induce tracheal cell basal lamina remodelling.
John C Means, A Lorena Passarelli

J Gen Virol· March 2014

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A case of ventral hernia mesh migration with splenosis mimicking a gastric mass.
Gavin A Falk, John Ryan Means, Auora Dawn Pryor

BMJ Case Rep· November 2011

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Synthesis and stereospecificity of 4,5-disubstituted oxazolidinone ligands binding to T-box riboswitch RNA.
Crina M Orac, Shu Zhou, John A Means, David Boehm, Stephen C Bergmeier

J Med Chem· October 2011

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Viral fibroblast growth factor, matrix metalloproteases, and caspases are associated with enhancing systemic infection by baculoviruses.
John C Means, A Lorena Passarelli

Proc Natl Acad Sci U S A· May 2010

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Obituary: Robert R. Zimmermann (1930-2009).
Stephanie J Coopman, John R Means

Am Psychol· April 2010

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Fluorescence probing of T box antiterminator RNA: insights into riboswitch discernment of the tRNA discriminator base.
John A Means, Crystal M Simson, Shu Zhou, Aaron A Rachford, Jeffrey J Rack

Biochem Biophys Res Commun· November 2009

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4,5-Disubstituted oxazolidinones: High affinity molecular effectors of RNA function.
Rajaneesh Anupam, Abhijit Nayek, Nicholas J Green, Frank J Grundy, Tina M Henkin, John A Means

Bioorg Med Chem Lett· June 2008

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Identification and functional characterization of AMVp33, a novel homolog of the baculovirus caspase inhibitor p35 found in Amsacta moorei entomopoxvirus.
John C Means, Taryn Penabaz, Rollie J Clem

Virology· February 2007

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T box riboswitch antiterminator affinity modulated by tRNA structural elements.
John A Means, Steffen Wolf, Akwasi Agyeman, Jeremy S Burton, Crystal M Simson

Chem Biol Drug Des· February 2007

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Carotid artery fibromuscular dysplasia.
Kurt R Stahlfeld, John R Means, Paul Didomenico

Am J Surg· January 2007

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Structure-activity studies of oxazolidinone analogs as RNA-binding agents.
John Means, Steven Katz, Abhijit Nayek, Rajaneesh Anupam, Jennifer V Hines

Bioorg Med Chem Lett· July 2006

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