Publications by authors named "John Neumeyer"

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The Non-Anhydrous, Minimally Basic Synthesis of the Dopamine D Agonist [18F]MCL-524.
James A H Inkster, Anna W Sromek, Vamsidhar Akurathi, John L Neumeyer, Alan B Packard

Chemistry (Basel)· September 2021

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The High Affinity Dopamine D Receptor Agonist MCL-536: A New Tool for Studying Dopaminergic Contribution to Neurological Disorders.
Sivan Subburaju, Anna W Sromek, Philip Seeman, John L Neumeyer

ACS Chem Neurosci· April 2021

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Identification of fluorinated (R)-(-)-aporphine derivatives as potent and selective ligands at serotonin 5-HT receptor.
Yulong Xu, Anna W Sromek, John L Neumeyer

Bioorg Med Chem Lett· January 2019

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New Dopamine D2 Receptor Agonist, [H]MCL-536, for Detecting Dopamine D2high Receptors in Vivo.
Sivan Subburaju, Anna W Sromek, Philip Seeman, John L Neumeyer

ACS Chem Neurosci· June 2018

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Oral r-(-)-11-o-valeryl-n-n-propylnoraporphine reverses motor deficits in mptp-treated marmosets.
Louise Lincoln, Ria Fisher, Michael J Jackson, Peter Jenner, John Neumeyer

Mov Disord· September 2016

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Convenient synthesis of 18F-radiolabeled R-(-)-N-n-propyl-2-(3-fluoropropanoxy-11-hydroxynoraporphine.
Anna W Sromek, Shaohui Zhang, Vamsidhar Akurathi, Alan B Packard, Wei Li, John L Neumeyer

J Labelled Comp Radiopharm· December 2014

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Pharmacological characterization and therapeutic potential for the treatment of opioid abuse with ATPM-ET, an N-ethyl substituted aminothiazolomorphinan with κ agonist and μ agonist/antagonist activity.
Jian-Feng Sun, Yu-Hua Wang, Jing-Rui Chai, Fu-Ying Li, Ai Hang, John L Neumeyer

Eur J Pharmacol· October 2014

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(18)F-MCL-524, an (18)F-Labeled Dopamine D2 and D3 Receptor Agonist Sensitive to Dopamine: A Preliminary PET Study.
Sjoerd J Finnema, Vladimir Stepanov, Ryuji Nakao, Anna W Sromek, Tangzhi Zhang, John L Neumeyer

J Nucl Med· July 2014

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Preliminary pharmacological evaluation of enantiomeric morphinans.
Anna W Sromek, Brian A Provencher, Shayla Russell, Elena Chartoff, Brian I Knapp, John L Neumeyer

ACS Chem Neurosci· February 2014

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Synthesis and pharmacological evaluation of aminothiazolomorphinans at the mu and kappa opioid receptors.
Brian A Provencher, Anna W Sromek, Wei Li, Shayla Russell, Elena Chartoff, John L Neumeyer

J Med Chem· November 2013

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Update 1 of: Recent progress in development of dopamine receptor subtype-selective agents: potential therapeutics for neurological and psychiatric disorders.
Na Ye, John L Neumeyer, Ross J Baldessarini, Xuechu Zhen, Ao Zhang

Chem Rev· May 2013

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Synthesis, binding affinity, and functional in vitro activity of 3-benzylaminomorphinan and 3-benzylaminomorphine ligands at opioid receptors.
John L Neumeyer, Bin Zhang, Tangzhi Zhang, Anna W Sromek, Brian I Knapp

J Med Chem· April 2012

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A tribute to Joseph G. Cannon, 1926-2011.
John L Neumeyer

J Med Chem· February 2012

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Synthesis and binding affinity of novel mono- and bivalent morphinan ligands for κ, μ, and δ opioid receptors.
Bin Zhang, Tangzhi Zhang, Anna W Sromek, Thomas Scrimale, Jean M Bidlack, John L Neumeyer

Bioorg Med Chem· May 2011

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Aminothiazolomorphinans with mixed κ and μ opioid activity.
Tangzhi Zhang, Zhaohua Yan, Anna Sromek, Brian I Knapp, Thomas Scrimale, John L Neumeyer

J Med Chem· March 2011

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Synthesis and Evaluation of Fluorinated Aporphines: Potential Positron Emission Tomography Ligands for D2 Receptors.
Anna W Sromek, Yu-Gui Si, Tangzhi Zhang, Susan R George, Philip Seeman, John L Neumeyer

ACS Med Chem Lett· March 2011

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Opioid bifunctional ligands from morphine and the opioid pharmacophore Dmt-Tic.
Gianfranco Balboni, Severo Salvadori, Ewa D Marczak, Brian I Knapp, Jean M Bidlack, John L Neumeyer

Eur J Med Chem· February 2011

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Effects of ATPM-ET, a novel κ agonist with partial μ activity, on physical dependence and behavior sensitization in mice.
Jian-feng SUN, Yu-hua WANG, Fu-ying LI, Gang LU, Yi-min TAO, John L NEUMEYER

Acta Pharmacol Sin· December 2010

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Rapid access to morphinones: removal of 4, 5-ether bridge with Pd-catalyzed triflate reduction.
Christopher D Hupp, John L Neumeyer

Tetrahedron Lett· April 2010

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Effect of linker substitution on the binding of butorphan univalent and bivalent ligands to opioid receptors.
Brian S Fulton, Brian L Knapp, Jean M Bidlack, John L Neumeyer

Bioorg Med Chem Lett· March 2010

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Evolution of the Bifunctional Lead μ Agonist / δ Antagonist Containing the Dmt-Tic Opioid Pharmacophore.
Gianfranco Balboni, Severo Salvadori, Claudio Trapella, Brian I Knapp, Jean M Bidlack, John L Neumeyer

ACS Chem Neurosci· February 2010

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Synthesis and opioid receptor binding affinities of 2-substituted and 3-aminomorphinans: ligands for mu, kappa, and delta opioid receptors.
Michael Decker, Yu-Gui Si, Brian I Knapp, Jean M Bidlack, John L Neumeyer

J Med Chem· January 2010

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Univalent and bivalent ligands of butorphan: characteristics of the linking chain determine the affinity and potency of such opioid ligands.
Michael Decker, Brian S Fulton, Bin Zhang, Brian I Knapp, Jean M Bidlack, John L Neumeyer

J Med Chem· December 2009

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Arylbenzazepines are potent modulators for the delayed rectifier K+ channel: a potential mechanism for their neuroprotective effects.
Xue-Qin Chen, Jing Zhang, John L Neumeyer, Guo-Zhang Jin, Guo-Yuan Hu

PLoS One· June 2009

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Pharmacological characterization of ATPM [(-)-3-aminothiazolo[5,4-b]-N-cyclopropylmethylmorphinan hydrochloride], a novel mixed kappa-agonist and mu-agonist/-antagonist that attenuates morphine antinociceptive tolerance and heroin self-administration behavior.
Yu-Jun Wang, Yi-Min Tao, Fu-Ying Li, Yu-Hua Wang, Xue-Jun Xu, John L Neumeyer

J Pharmacol Exp Ther· April 2009

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