Publications by authors named "John Wort"

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Paediatric pulmonary arterial hypertension following congenital heart defect repair: Enhanced risk stratification and outcomes in a national cohort.
Andrew Constantine, Konstantinos Dimopoulos, Robin Condliffe, Paul Clift, Katrijn Jansen, S John Wort

Eur Heart J Qual Care Clin Outcomes· December 2025

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GDF15 is a putative biomarker for distinguishing pulmonary veno-occlusive disease and pulmonary arterial hypertension.
Amit Prabhakar, Eckart Mdd De Bie, Jacqueline T DesJardin, Prajakta Ghatpande, Stefan Gräf, S John Wort

J Clin Invest· November 2025

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Survival in patients with pulmonary hypertension associated with fibrotic interstitial lung disease (ILD) is independent of ILD subtype.
Ifan Jenkin, Konstantinos Dimopoulos, Steven D Nathan, Sophie Herbert, Timothy Dawes, S John Wort

ERJ Open Res· November 2025

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Significance of Pulmonary Vascular Dysfunction in Chronic Obstructive Pulmonary Disease.
Steven D Nathan, Lucilla Piccari, Steven H Abman, Aparna Balasubramanian, Reda E Girgis, S John Wort

Pulm Circ· July 2025

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Positioning Imatinib for Pulmonary Arterial Hypertension: A Dose-Finding Phase 2 Study.
Alexander M K Rothman, Sofia S Villar, Jennifer Middleton, Andreas A Roussakis, Frances Varian, S John Wort

Am J Respir Crit Care Med· June 2025

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New therapies in pulmonary arterial hypertension: Recent insights.
Giulia Guglielmi, Konstantinos Dimopoulos, S John Wort

Int J Cardiol Congenit Heart Dis· March 2025

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Inhaled soluble guanylate cyclase stimulator for the treatment of pulmonary arterial hypertension: struggling to breathe easy.
Colm McCabe, S John Wort

Eur Respir J· November 2024

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Noninvasive diagnostic modalities and prediction models for detecting pulmonary hypertension associated with interstitial lung disease: a narrative review.
Alexandra Arvanitaki, Gerhard Paul Diller, Michael A Gatzoulis, Colm McCabe, Laura C Price, S John Wort

Eur Respir Rev· October 2024

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The hepcidin-ferroportin axis influences mitochondrial function, proliferation, and migration in pulmonary artery endothelial and smooth muscle cells.
Theo Issitt, Quezia K Toe, Sofia L Pedersen, Thomas Shackshaft, Maziah Mohd Ghazaly, S John Wort

Pulm Circ· October 2024

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The impact of cardiovascular and lung comorbidities in patients with pulmonary arterial hypertension: A systematic review and meta-analysis.
Ioannis Gialamas, Alexandra Arvanitaki, Stephan Rosenkranz, S John Wort, Göran Rådegran

J Heart Lung Transplant· September 2024

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Use of pulmonary arterial hypertension therapies in patient swith sarcoidosis-associated pulmonary hypertension.
Laura C Price, Vaileios Kouranos, Robert Baughman, Chloe Bloom, Iain Stewart, S John Wort

Sarcoidosis Vasc Diffuse Lung Dis· March 2024

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Pulmonary Hypertension: Intensification and Personalization of Combination Rx (PHoenix): A phase IV randomized trial for the evaluation of dose-response and clinical efficacy of riociguat and selexipag using implanted technologies.
Frances Varian, Jennifer Dick, Christian Battersby, Stefan Roman, Jenna Ablott, John Wort

Pulm Circ· January 2024

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Chaotic breathing in post-COVID-19 breathlessness: a key feature of dysfunctional breathing can be characterised objectively by approximate entropy.
Chinthaka B Samaranayake, Christopher Warren, Serena Rhamie, Gulam Haji, S John Wort

ERJ Open Res· July 2023

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Differential responses of pulmonary vascular cells from PAH patients and controls to TNFα and the effect of the BET inhibitor JQ1.
Sharon Mumby, Frederic Perros, Julien Grynblat, Gregoire Manaud, Alberto Papi, S John Wort

Respir Res· July 2023

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Autoimmunity Is a Significant Feature of Idiopathic Pulmonary Arterial Hypertension.
Rowena J Jones, Eckart M D D De Bie, Emily Groves, Kasia I Zalewska, Emilia M Swietlik, S John Wort

Am J Respir Crit Care Med· July 2022

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Use of sildenafil in patients with severe COVID-19 pneumonitis.
Charles McFadyen, Ben Garfield, Jennifer Mancio, Carole A Ridge, Tom Semple, S John Wort

Br J Anaesth· July 2022

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Different Cytokine Patterns in BMPR2-Mutation-Positive Patients and Patients With Pulmonary Arterial Hypertension Without Mutations and Their Influence on Survival.
Max Schwiening, Emilia M Swietlik, Divya Pandya, Keith Burling, Peter Barker, S John Wort

Chest· June 2022

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Mendelian randomisation and experimental medicine approaches to interleukin-6 as a drug target in pulmonary arterial hypertension.
Mark Toshner, Colin Church, Lars Harbaum, Christopher Rhodes, Sofia S Villar Moreschi, S John Wort

Eur Respir J· March 2022

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Establishing expert consensus for the optimal approach to holistic risk-management in pulmonary arterial hypertension: a Delphi process and narrative review.
Colin Church, Wendy Gin-Sing, Duncan Grady, Martin Johnson, David G Kiely, S John Wort

Expert Rev Respir Med· November 2021

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Pulmonary arterial hypertension in adults with congenital heart disease: markers of disease severity, management of advanced heart failure and transplantation.
Katrijn Jansen, Andrew Constantine, Robin Condliffe, Robert Tulloh, Paul Clift, S John Wort

Expert Rev Cardiovasc Ther· September 2021

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A case series on the use of steroids and mycophenolate mofetil in idiopathic and heritable pulmonary veno-occlusive disease: is there a role for immunosuppression?
Carmel Bergbaum, Chinthaka B Samaranayake, Alex Pitcher, Emma Weingart, Thomas Semple, S John Wort

Eur Respir J· June 2021

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Pulmonary vasodilator treatment in pulmonary hypertension due to left heart or lung disease: time for a high-definition picture?
Lucilla Piccari, Roberto J Bernardo, Diego Rodríguez-Chiaradía, Patrizio Vitulo, S John Wort

Pulm Circ· May 2021

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Potential for personalised application of inhaled nitric oxide in COVID-19 pneumonia.
Benjamin Garfield, Charles McFadyen, Charlotte Briar, Caroline Bleakley, Aikaterini Vlachou, S John Wort

Br J Anaesth· February 2021

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Corona Virus Disease 2019 arterial and venous thrombosis in critically ill patients: a case series.
Mireya Castro-Verdes, Antonia Gkouma, John Wort, Carole Ridge, Saeed Mirsadraee

Eur Heart J Case Rep· December 2020

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Covid-19 pneumonia and pulmonary vascular disease: A UK Centre perspective.
S John Wort, D J Arachchillage, C McCabe, L C Price

Respir Med Res· November 2020

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