Publications by authors named "Joice Thomas"

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Discovery and Characterization of Potent, Selective, and Orally Bioavailable 7-Azaindazole AXL Receptor Tyrosine Kinase Inhibitors.
Corinne N Foley, Shiwei Qu, Srinivas Reddy Paladugu, Manjunath Lamani, Rebecca Grange, Joice Thomas

J Med Chem· June 2025

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Discovery of AB801, a Potent and Selective Inhibitor of AXL Receptor Tyrosine Kinase for Use in Cancer Therapy.
Dillon H Miles, Manjunath Lamani, Srinivas Reddy Paladugu, Shiwei Qu, Corinne N Foley, Joice Thomas

J Med Chem· June 2025

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Discovery of a novel androgen receptor antagonist, MEL-6, with stereoselective activity and optimization of its metabolic stability.
Christine Helsen, Konstantina Karypidou, Joice Thomas, Wout De Leger, Tien Nguyen

J Steroid Biochem Mol Biol· May 2024

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Virtual Screening of a Chemically Diverse "Superscaffold" Library Enables Ligand Discovery for a Key GPCR Target.
Katharina Grotsch, Anastasiia V Sadybekov, Sydney Hiller, Saheem Zaidi, Dmitry Eremin, Joice Thomas

ACS Chem Biol· April 2024

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Advances in the Synthesis of Fused 1,2,3-Triazoles via a MCR-Intramolecular Azide-Alkyne Cycloaddition Approach.
Rahul P, Joice Thomas, Wim Dehaen, Jubi John

Molecules· December 2022

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Synthesis of homochiral sulfanyl- and sulfoxide-substituted naphthyltriazoles and study of the conformational stability.
Robby Vroemans, Sergio R Ribone, Joice Thomas, Luc Van Meervelt, Thierry Ollevier

Org Biomol Chem· July 2021

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Betulonic Acid Derivatives Interfering with Human Coronavirus 229E Replication via the nsp15 Endoribonuclease.
Annelies Stevaert, Besir Krasniqi, Benjamin Van Loy, Tien Nguyen, Joice Thomas

J Med Chem· May 2021

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DNA-SIP and repeated isolation corroborate Variovorax as a key organism in maintaining the genetic memory for linuron biodegradation in an agricultural soil.
Harry Lerner, Başak Öztürk, Anja B Dohrmann, Joice Thomas, Kathleen Marchal

FEMS Microbiol Ecol· April 2021

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Culture-Independent Analysis of Linuron-Mineralizing Microbiota and Functions in on-Farm Biopurification Systems via DNA-Stable Isotope Probing: Comparison with Enrichment Culture.
Harry Lerner, Başak Öztürk, Anja B Dohrmann, Joice Thomas, Kathleen Marchal

Environ Sci Technol· August 2020

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Synthesis and post-functionalization of alternate-linked-[2 .1 ]thiacyclophanes.
Wout De Leger, Koen Adriaensen, Koen Robeyns, Luc Van Meervelt, Joice Thomas

Beilstein J Org Chem· August 2018

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Regioselective Synthesis of Fluorosulfonyl 1,2,3-Triazoles from Bromovinylsulfonyl Fluoride.
Joice Thomas, Valery V Fokin

Org Lett· July 2018

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Straightforward synthesis of enantiomerically pure 1,2,3-triazoles derived from amino esters.
Gastón Silveira-Dorta, Sampad Jana, Lucie Borkova, Joice Thomas, Wim Dehaen

Org Biomol Chem· May 2018

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Sequential Ugi reaction/base-induced ring closing/IAAC protocol toward triazolobenzodiazepine-fused diketopiperazines and hydantoins.
Robby Vroemans, Fante Bamba, Jonas Winters, Joice Thomas, Jeroen Jacobs

Beilstein J Org Chem· March 2018

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2-Amino-3-methylcarboxy-5-heptyl-thiophene (TJ191) is a selective anti-cancer small molecule that targets low TβRIII-expressing malignant T-cell leukemia/lymphoma cells.
Ahmed El-Gazzar, Sam Noppen, Joice Thomas, Wim Dehaen, Jan Balzarini

Oncotarget· January 2018

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Synthesis and anticancer activity of novel aza-artemisinin derivatives.
Sampad Jana, Shabina Iram, Joice Thomas, Sandra Liekens, Wim Dehaen

Bioorg Med Chem· July 2017

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Pronounced anti-proliferative activity and tumor cell selectivity of 5-alkyl-2-amino-3-methylcarboxylate thiophenes.
Joice Thomas, Alenka Jecic, Els Vanstreels, Lizette van Berckelaer, Romeo Romagnoli

Eur J Med Chem· May 2017

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A new four-component reaction involving the Michael addition and the Gewald reaction, leading to diverse biologically active 2-aminothiophenes.
Joice Thomas, Sampad Jana, Mahendra Sonawane, Bert Fiey, Jan Balzarini

Org Biomol Chem· May 2017

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Acid-Sensitive BODIPY Dyes: Synthesis through Pd-Catalyzed Direct C(sp )-H Arylation and Photophysics.
Hui Chong, Eduard Fron, Zhen Liu, Stijn Boodts, Joice Thomas

Chemistry· April 2017

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Selective alkaline stripping of metal ions after solvent extraction by base-stable 1,2,3-triazolium ionic liquids.
Stijn Raiguel, Daphne Depuydt, Tom Vander Hoogerstraete, Joice Thomas, Wim Dehaen

Dalton Trans· April 2017

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Application of the Triazolization Reaction to Afford Dihydroartemisinin Derivatives with Anti-HIV Activity.
Sampad Jana, Shabina Iram, Joice Thomas, Muhammad Qasim Hayat, Christophe Pannecouque

Molecules· February 2017

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A One-Pot Procedure for the Synthesis of "Click-Ready" Triazoles from Ketones.
Sampad Jana, Joice Thomas, Wim Dehaen

J Org Chem· December 2016

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Metal-Free Route for the Synthesis of 4-Acyl-1,2,3-Triazoles from Readily Available Building Blocks.
Joice Thomas, Vince Goyvaerts, Sandra Liekens, Wim Dehaen

Chemistry· July 2016

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A single-step acid catalyzed reaction for rapid assembly of NH-1,2,3-triazoles.
Joice Thomas, Sampad Jana, Sandra Liekens, Wim Dehaen

Chem Commun (Camb)· July 2016

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A general metal-free route towards the synthesis of 1,2,3-triazoles from readily available primary amines and ketones.
Joice Thomas, Sampad Jana, Jubi John, Sandra Liekens, Wim Dehaen

Chem Commun (Camb)· February 2016

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Homodiselenacalix[4]arenes: Molecules with Unique Channelled Crystal Structures.
Joice Thomas, Liliana Dobrzańska, Luc Van Meervelt, Mario Alfredo Quevedo, Krzysztof Woźniak

Chemistry· January 2016

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