Publications by authors named "Joma Joy"

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Correction to "Discovery of an Orally Bioavailable Reversible Covalent SARS-CoV-2 M Inhibitor with Pan-Coronavirus Activity".
Qian Wen Tan, Subramanyam Vankadara, Jia Yi Fong, Yi Yang See, Nithya Baburajendran, Joma Joy

J Med Chem· January 2026

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Discovery of an Orally Bioavailable Reversible Covalent SARS-CoV-2 M Inhibitor with Pan-Coronavirus Activity.
Qian Wen Tan, Subramanyam Vankadara, Jia Yi Fong, Yi Yang See, Nithya Baburajendran, Joma Joy

J Med Chem· August 2025

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Button-Push On-Demand Synthesis for Rapid Optimization of Antiviral Peptidomimetics.
Duanshuai Tian, Ting Wei Tan, Ronald Toh Kuan Hai, Gan Wang, Fadhil Peer Mohamed, Joma Kanikadu Joy

J Am Chem Soc· November 2024

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A Warhead Substitution Study on the Coronavirus Main Protease Inhibitor Nirmatrelvir.
Subramanyam Vankadara, Monique Danielle Dawson, Jia Yi Fong, Qin Yao Oh, Qi An Ang, Joma Joy

ACS Med Chem Lett· August 2022

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Structure-activity relationship studies of allosteric inhibitors of EYA2 tyrosine phosphatase.
Jothi Anantharajan, Nithya Baburajendran, Grace Lin, Yong Yao Loh, Weijun Xu, Joma Joy

Protein Sci· February 2022

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Fragment-based lead discovery of indazole-based compounds as AXL kinase inhibitors.
Pearly Shuyi Ng, Klement Foo, Sandra Sim, Gang Wang, Chuhui Huang, Joma Joy

Bioorg Med Chem· November 2021

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A head-to-head comparison of the inhibitory activities of 15 peptidomimetic SARS-CoV-2 3CLpro inhibitors.
Subramanyam Vankadara, Yun Xuan Wong, Boping Liu, Yi Yang See, Li Hong Tan, Joma Joy

Bioorg Med Chem Lett· September 2021

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Strategic Design of Catalytic Lysine-Targeting Reversible Covalent BCR-ABL Inhibitors*.
David Quach, Guanghui Tang, Jothi Anantharajan, Nithya Baburajendran, Anders Poulsen, Joma K Joy

Angew Chem Int Ed Engl· July 2021

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Stepwise Evolution of Fragment Hits against MAPK Interacting Kinases 1 and 2.
Jacek Kwiatkowski, Boping Liu, Shermaine Pang, Nur Huda Binte Ahmad, Gang Wang, Joma Joy

J Med Chem· January 2020

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Structural and Functional Analyses of an Allosteric EYA2 Phosphatase Inhibitor That Has On-Target Effects in Human Lung Cancer Cells.
Jothi Anantharajan, Hengbo Zhou, Lingdi Zhang, Taylor Hotz, Melanie Y Vincent, Joma Joy

Mol Cancer Ther· September 2019

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Correction to "Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3".
Chuhui Huang, Si Si Liew, Grace R Lin, Anders Poulsen, Melgious J Y Ang, Joma Joy

ACS Med Chem Lett· August 2019

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Discovery of Irreversible Inhibitors Targeting Histone Methyltransferase, SMYD3.
Chuhui Huang, Si Si Liew, Grace R Lin, Anders Poulsen, Melgious J Y Ang, Joma Joy

ACS Med Chem Lett· June 2019

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Targeting cancer addiction for SALL4 by shifting its transcriptome with a pharmacologic peptide.
Bee Hui Liu, Chacko Jobichen, C S Brian Chia, Tim Hon Man Chan, Jing Ping Tang, Joma Joy

Proc Natl Acad Sci U S A· July 2018

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Optimization of Selective Mitogen-Activated Protein Kinase Interacting Kinases 1 and 2 Inhibitors for the Treatment of Blast Crisis Leukemia.
Haiyan Yang, Lohitha Rao Chennamaneni, Melvyn Wai Tuck Ho, Shi Hua Ang, Eldwin Sum Wai Tan, Joma Kanikadu Joy

J Med Chem· May 2018

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Backbone resonance assignments for the SET domain of human methyltransferase NSD3 in complex with its cofactor.
Yan Li, Hui Qi Ng, Anna Ngo, Shuang Liu, Yih Wan Tan, Joma Joy

Biomol NMR Assign· October 2017

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Discovery and characterisation of the automethylation properties of PRDM9.
Xiaoying Koh-Stenta, Anders Poulsen, Rong Li, John Liang Kuan Wee, Perlyn Zekui Kwek, Joma Joy

Biochem J· March 2017

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Miniature bovine pancreatic trypsin inhibitors (m-BPTIs) of the West Nile virus NS2B-NS3 protease.
Melgious J Y Ang, Huichang A Lim, Anders Poulsen, John Liang Kuan Wee, Fui Mee Ng, Joma Joy

J Enzyme Inhib Med Chem· February 2017

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Identification of covalent active site inhibitors of dengue virus protease.
Xiaoying Koh-Stenta, Joma Joy, Si Fang Wang, Perlyn Zekui Kwek, John Liang Kuan Wee

Drug Des Devel Ther· September 2016

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Structure-Activity Relationship Studies of Mitogen Activated Protein Kinase Interacting Kinase (MNK) 1 and 2 and BCR-ABL1 Inhibitors Targeting Chronic Myeloid Leukemic Cells.
Joseph Cherian, Kassoum Nacro, Zhi Ying Poh, Samantha Guo, Duraiswamy A Jeyaraj, Joma Kanikadu Joy

J Med Chem· April 2016

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Antiviral activities of 15 dengue NS2B-NS3 protease inhibitors using a human cell-based viral quantification assay.
Justin Jang Hann Chu, Regina Ching Hua Lee, Melgious Jin Yan Ang, Wei-Ling Wang, Huichang Annie Lim, Joma Joy

Antiviral Res· June 2015

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Characterization of the histone methyltransferase PRDM9 using biochemical, biophysical and chemical biology techniques.
Xiaoying Koh-Stenta, Joma Joy, Anders Poulsen, Rong Li, Yvonne Tan

Biochem J· July 2014

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A P2 and P3 substrate specificity comparison between the Murray Valley encephalitis and West Nile virus NS2B/NS3 protease using C-terminal agmatine dipeptides.
Melgious Jin Yan Ang, Zhitao Li, Huichang Annie Lim, Fui Mee Ng, Siew Wen Then, Joma Joy

Peptides· February 2014

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Lyso-myristoyl phosphatidylcholine micelles sustain the activity of Dengue non-structural (NS) protein 3 protease domain fused with the full-length NS2B.
Qiwei Huang, Qingxin Li, Joma Joy, Angela Shuyi Chen, David Ruiz-Carrillo

Protein Expr Purif· December 2013

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Substrate-based peptidomimetic inhibitors of the Murray Valley encephalitis virus NS2B/NS3 serine protease: a P1-P4 SAR study.
Melgious Jin Yan Ang, Gerald Han Jie Yong, Anders Poulsen, Siew Wen Then, Zhitao Li, Joma Joy

Eur J Med Chem· October 2013

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Rational design of resorcylic acid lactone analogues as covalent MNK1/2 kinase inhibitors by tuning the reactivity of an enamide Michael acceptor.
Jin Xu, Anqi Chen, Joma Joy, Vanessa Joanne Xavier, Esther H Q Ong

ChemMedChem· September 2013

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