Publications by authors named "Jomon Sebastian"

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Microtubules and Cell Division: Potential Pharmacological Targets in Cancer Therapy.
Jomon Sebastian, Krishnan Rathinasamy

Curr Drug Targets· August 2023

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MD simulation-based screening approach identified tolvaptan as a potential inhibitor of Eg5.
Jomon Sebastian, Darpan Raghav, Krishnan Rathinasamy

Mol Divers· June 2023

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Cytotoxic mechanism of tioconazole involves cell cycle arrest at mitosis through inhibition of microtubule assembly.
Jomon Sebastian, Krishnan Rathinasamy

Cytotechnology· February 2022

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Sertaconazole induced toxicity in HeLa cells through mitotic arrest and inhibition of microtubule assembly.
Jomon Sebastian, Krishnan Rathinasamy

Naunyn Schmiedebergs Arch Pharmacol· June 2021

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Corrigendum to "Biochemical and biophysical characterization of curcumin binding to human mitotic kinesin Eg5: Insights into the inhibitory mechanism of curcumin on Eg5" [Int. J. Biol. Macromol. 109 (2018) 1189-1208].
Darpan Raghav, Jomon Sebastian, Krishnan Rathinasamy

Int J Biol Macromol· May 2020

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Benserazide Perturbs Kif15-kinesin Binding Protein Interaction with Prolonged Metaphase and Defects in Chromosomal Congression: A Study Based on in silico Modeling and Cell Culture.
Jomon Sebastian, Krishnan Rathinasamy

Mol Inform· March 2020

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Corrigendum to "Biochemical and Biophysical characterization of curcumin binding to human mitotic kinesin Eg5: Insights into the inhibitory mechanism of curcumin on Eg5" [Int. J. Biol. Macromol. 109 (2018) 1189-1208].
Darpan Raghav, Jomon Sebastian, Krishnan Rathinasamy

Int J Biol Macromol· January 2020

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Zerumbone, a cyclic sesquiterpene, exerts antimitotic activity in HeLa cells through tubulin binding and exhibits synergistic activity with vinblastine and paclitaxel.
Shabeeba M Ashraf, Jomon Sebastian, Krishnan Rathinasamy

Cell Prolif· March 2019

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Indirubin, a bis-indole alkaloid binds to tubulin and exhibits antimitotic activity against HeLa cells in synergism with vinblastine.
Lakshmi Mohan, Darpan Raghav, Shabeeba M Ashraf, Jomon Sebastian, Krishnan Rathinasamy

Biomed Pharmacother· September 2018

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Biochemical and Biophysical characterization of curcumin binding to human mitotic kinesin Eg5: Insights into the inhibitory mechanism of curcumin on Eg5.
Darpan Raghav, Jomon Sebastian, Krishnan Rathinasamy

Int J Biol Macromol· April 2018

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Structure-Activity Relationship Study Reveals Benzazepine Derivatives of Luteolin as New Aldose Reductase Inhibitors for Diabetic Cataract.
Jomon Sebastian

Curr Drug Discov Technol· August 2017

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Dihydropyrazole and dihydropyrrole structures based design of Kif15 inhibitors as novel therapeutic agents for cancer.
Jomon Sebastian

Comput Biol Chem· June 2017

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Parmotrema tinctorum exhibits antioxidant, antiglycation and inhibitory activities against aldose reductase and carbohydrate digestive enzymes: an in vitro study.
P Salin Raj, A Prathapan, Jomon Sebastian, Antu K Antony, Mariam Philip Riya

Nat Prod Res· December 2014

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