Publications by authors named "Jon Coffman"

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I
Improved sieving coefficient in perfusion cell culture with reduced effective filtration length of hollow fibers.
Jimmy Vu, J Alex Gadberry, Jon Coffman, Ken Lee

Biotechnol Prog· October 2024

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Effect of inner diameter, filter length, and pore size on hollow fiber filter fouling during perfusion cell culture.
Dominique WuDunn, Andrea Squeri, Jimmy Vu, Ashna Dhingra, Jon Coffman

Biotechnol Prog· June 2024

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Fully integrated downstream process to enable next-generation manufacturing.
Irina Ramos, Nikunj Sharda, Ramon Villafana, Kevin Hill-Byrne, Kang Cai, Jon Coffman

Biotechnol Bioeng· July 2023

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Leveraging mathematical models for optimizing filter utility at manufacturing scale.
Steven Rose, Ashna Dhingra, Adrian Joseph, Jon Coffman

Biotechnol Bioeng· June 2023

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Generation of reference cell lines, media, and a process platform for CHO cell biomanufacturing.
Lauren T Cordova, Hussain Dahodwala, Kathryn S Elliott, Jongyoun Baik, Daniel C Odenewelder, Jon Coffman

Biotechnol Bioeng· March 2023

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End-to-end collaboration to transform biopharmaceutical development and manufacturing.
John Erickson, Jeffrey Baker, Shawn Barrett, Ciaran Brady, Mark Brower, Jon Coffman

Biotechnol Bioeng· September 2021

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The design basis for the integrated and continuous biomanufacturing framework.
Jon Coffman, Kenneth Bibbo, Mark Brower, Robert Forbes, Nicholas Guros

Biotechnol Bioeng· September 2021

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Benchmarking biopharmaceutical process development and manufacturing cost contributions to R&D.
Suzanne S Farid, Max Baron, Christos Stamatis, Wenhao Nie, Jon Coffman

MAbs· May 2021

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Leveraging flow mechanics to determine critical process and scaling parameters in a continuous viral inactivation reactor.
Matthew R Brown, Raquel Orozco, Jon Coffman

Biotechnol Bioeng· March 2020

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Novel, linked bioreactor system for continuous production of biologics.
Matthew Gagnon, Shashikant Nagre, Wenge Wang, Jon Coffman, Gregory W Hiller

Biotechnol Bioeng· August 2019

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Impact of Dean Vortices on the Integrity Testing of a Continuous Viral Inactivation Reactor.
Linus Amarikwa, Raquel Orozco, Matthew Brown, Jon Coffman

Biotechnol J· February 2019

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Larger Pore Size Hollow Fiber Membranes as a Solution to the Product Retention Issue in Filtration-Based Perfusion Bioreactors.
Samantha B Wang, Scott Godfrey, Flaka Radoniqi, Henry Lin, Jon Coffman

Biotechnol J· February 2019

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C
Computational fluid dynamic modeling of alternating tangential flow filtration for perfusion cell culture.
Flaka Radoniqi, Hu Zhang, Cameron L Bardliving, Parviz Shamlou, Jon Coffman

Biotechnol Bioeng· November 2018

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D
Design of a novel continuous flow reactor for low pH viral inactivation.
Stephanie A Parker, Linus Amarikwa, Kevin Vehar, Raquel Orozco, Scott Godfrey, Jon Coffman

Biotechnol Bioeng· March 2018

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D
Design, construction, and optimization of a novel, modular, and scalable incubation chamber for continuous viral inactivation.
Raquel Orozco, Scott Godfrey, Jon Coffman, Linus Amarikwa, Stephanie Parker

Biotechnol Prog· July 2017

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Integrated continuous bioprocessing: Economic, operational, and environmental feasibility for clinical and commercial antibody manufacture.
James Pollock, Jon Coffman, Sa V Ho, Suzanne S Farid

Biotechnol Prog· July 2017

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Shear contributions to cell culture performance and product recovery in ATF and TFF perfusion systems.
Samantha Wang, Scott Godfrey, Janani Ravikrishnan, Henry Lin, Jens Vogel, Jon Coffman

J Biotechnol· March 2017

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A
A tandem laboratory scale protein purification process using Protein A affinity and anion exchange chromatography operated in a weak partitioning mode.
Michael Shamashkin, Ranga Godavarti, Timothy Iskra, Jon Coffman

Biotechnol Bioeng· October 2013

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Optimising the design and operation of semi-continuous affinity chromatography for clinical and commercial manufacture.
James Pollock, Glen Bolton, Jon Coffman, Sa V Ho, Daniel G Bracewell

J Chromatogr A· April 2013

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High-throughput screening of chromatographic separations: III. Monoclonal antibodies on ceramic hydroxyapatite.
David L Wensel, Brian D Kelley, Jon L Coffman

Biotechnol Bioeng· August 2008

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High-throughput screening of chromatographic separations: IV. Ion-exchange.
Brian D Kelley, Mary Switzer, Patrick Bastek, Jack F Kramarczyk, Kathleen Molnar, Jon Coffman

Biotechnol Bioeng· August 2008

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