Publications by authors named "Jon D Gaffaney"

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Lipid-anchored Synaptobrevin Provides Little or No Support for Exocytosis or Liposome Fusion.
Che-Wei Chang, Chung-Wei Chiang, Jon D Gaffaney, Edwin R Chapman, Meyer B Jackson

J Biol Chem· February 2016

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Structural elements that underlie Doc2β function during asynchronous synaptic transmission.
Renhao Xue, Jon D Gaffaney, Edwin R Chapman

Proc Natl Acad Sci U S A· August 2015

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Antagonist-induced conformational changes in dopamine transporter extracellular loop two involve residues in a potential salt bridge.
Jon D Gaffaney, Madhur Shetty, Bruce Felts, Akula-Bala Pramod, James D Foster

Neurochem Int· July 2014

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Mutations that disrupt Ca²⁺-binding activity endow Doc2β with novel functional properties during synaptic transmission.
Jon D Gaffaney, Renhao Xue, Edwin R Chapman

Mol Biol Cell· February 2014

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Uncoupling the roles of synaptotagmin I during endo- and exocytosis of synaptic vesicles.
Jun Yao, Sung E Kwon, Jon D Gaffaney, F Mark Dunning, Edwin R Chapman

Nat Neurosci· December 2011

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Doc2 is a Ca2+ sensor required for asynchronous neurotransmitter release.
Jun Yao, Jon D Gaffaney, Sung E Kwon, Edwin R Chapman

Cell· October 2011

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Mechanism and function of synaptotagmin-mediated membrane apposition.
Enfu Hui, Jon D Gaffaney, Zhao Wang, Colin P Johnson, Chantell S Evans

Nat Struct Mol Biol· June 2011

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Synaptotagmin C2B domain regulates Ca2+-triggered fusion in vitro: critical residues revealed by scanning alanine mutagenesis.
Jon D Gaffaney, F Mark Dunning, Zhao Wang, Enfu Hui, Edwin R Chapman

J Biol Chem· November 2008

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Labeling of dopamine transporter transmembrane domain 1 with the tropane ligand N-[4-(4-azido-3-[125I]iodophenyl)butyl]-2beta-carbomethoxy-3beta-(4-chlorophenyl)tropane implicates proximity of cocaine and substrate active sites.
M Laura Parnas, Jon D Gaffaney, Mu Fa Zou, John R Lever, Amy Hauck Newman

Mol Pharmacol· April 2008

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Affinity labeling the dopamine transporter ligand binding site.
Roxanne A Vaughan, M Laura Parnas, Jon D Gaffaney, Margaret J Lowe, Sara Wirtz

J Neurosci Methods· April 2005

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Uptake inhibitors but not substrates induce protease resistance in extracellular loop two of the dopamine transporter.
Jon D Gaffaney, Roxanne A Vaughan

Mol Pharmacol· March 2004

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