Publications by authors named "Jon D Larson"

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Preservation and Clonal Behavior of Extrachromosomal DNA in Patient-Derived Xenograft Models of Childhood Cancers.
Rishaan Kenkre, Jon D Larson, Owen S Chapman, Jens Luebeck, Yan Yuen Lo

bioRxiv· August 2025

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Central Nervous System Distribution of Panobinostat in Preclinical Models to Guide Dosing for Pediatric Brain Tumors.
Wenqiu Zhang, Ju-Hee Oh, Wenjuan Zhang, Sneha Rathi, Jon D Larson

J Pharmacol Exp Ther· December 2023

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Circular extrachromosomal DNA promotes tumor heterogeneity in high-risk medulloblastoma.
Owen S Chapman, Jens Luebeck, Sunita Sridhar, Ivy Tsz-Lo Wong, Deobrat Dixit, Jon D Larson

Nat Genet· December 2023

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N-myc-Mediated Translation Control Is a Therapeutic Vulnerability in Medulloblastoma.
Duygu Kuzuoglu-Ozturk, Ozlem Aksoy, Christin Schmidt, Robin Lea, Jon D Larson

Cancer Res· January 2023

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Integrated genome and tissue engineering enables screening of cancer vulnerabilities in physiologically relevant perfusable ex vivo cultures.
Michael Hu, Xin Yi Lei, Jon D Larson, Melissa McAlonis, Kyle Ford

Biomaterials· January 2022

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ChIPseqSpikeInFree: a ChIP-seq normalization approach to reveal global changes in histone modifications without spike-in.
Hongjian Jin, Lawryn H Kasper, Jon D Larson, Gang Wu, Suzanne J Baker

Bioinformatics· February 2020

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Correction to: H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.
André B Silveira, Lawryn H Kasper, Yiping Fan, Hongjian Jin, Gang Wu, Jon D Larson

Acta Neuropathol· June 2019

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Engineering Inducible Knock-In Mice to Model Oncogenic Brain Tumor Mutations from Endogenous Loci.
Jon D Larson, Suzanne J Baker

Methods Mol Biol· May 2019

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H3.3 K27M depletion increases differentiation and extends latency of diffuse intrinsic pontine glioma growth in vivo.
André B Silveira, Lawryn H Kasper, Yiping Fan, Hongjian Jin, Gang Wu, Jon D Larson

Acta Neuropathol· April 2019

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Insertional Mutagenesis Reveals Important Genetic Drivers of Central Nervous System Embryonal Tumors.
Pauline J Beckmann, Jon D Larson, Alex T Larsson, Jason P Ostergaard, Sandra Wagner

Cancer Res· March 2019

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Histone H3.3 K27M Accelerates Spontaneous Brainstem Glioma and Drives Restricted Changes in Bivalent Gene Expression.
Jon D Larson, Lawryn H Kasper, Barbara S Paugh, Hongjian Jin, Gang Wu

Cancer Cell· January 2019

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PTEN Signaling in the Postnatal Perivascular Progenitor Niche Drives Medulloblastoma Formation.
Guo Zhu, Sherri L Rankin, Jon D Larson, Xiaoyan Zhu, Lionel M L Chow

Cancer Res· January 2017

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Review: In vivo models for defining molecular subtypes of the primitive neuroectodermal tumor genome: current challenges and solutions.
Jon D Larson, David A Largaespada

In Vivo· January 2013

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The lineage-specific gene ponzr1 is essential for zebrafish pronephric and pharyngeal arch development.
Victoria M Bedell, Anthony D Person, Jon D Larson, Anna McLoon, Darius Balciunas

Development· February 2012

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Moesin1 and Ve-cadherin are required in endothelial cells during in vivo tubulogenesis.
Ying Wang, Mark S Kaiser, Jon D Larson, Aidas Nasevicius, Karl J Clark

Development· September 2010

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Sleeping beauty-mediated somatic mutagenesis implicates CSF1 in the formation of high-grade astrocytomas.
Aaron M Bender, Lara S Collier, Fausto J Rodriguez, Christina Tieu, Jon D Larson

Cancer Res· May 2010

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Combination of reverse and chemical genetic screens reveals angiogenesis inhibitors and targets.
Mattias Kalén, Elisabet Wallgard, Noomi Asker, Aidas Nasevicius, Elisabet Athley, Jon D Larson

Chem Biol· April 2009

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De novo induction of genetically engineered brain tumors in mice using plasmid DNA.
Stephen M Wiesner, Stacy A Decker, Jon D Larson, Katya Ericson, Colleen Forster

Cancer Res· January 2009

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p53 activation by knockdown technologies.
Mara E Robu, Jon D Larson, Aidas Nasevicius, Soraya Beiraghi, Charles Brenner

PLoS Genet· May 2007

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Genome-wide reverse genetics framework to identify novel functions of the vertebrate secretome.
Michael A Pickart, Eric W Klee, Aubrey L Nielsen, Sridhar Sivasubbu, Eric M Mendenhall, Jon D Larson

PLoS One· December 2006

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Functional analysis of zebrafish microfibril-associated glycoprotein-1 (Magp1) in vivo reveals roles for microfibrils in vascular development and function.
Eleanor Chen, Jon D Larson, Stephen C Ekker

Blood· June 2006

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Expression of VE-cadherin in zebrafish embryos: a new tool to evaluate vascular development.
Jon D Larson, Shannon A Wadman, Eleanor Chen, Lesa Kerley, Karl J Clark

Dev Dyn· September 2004

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Zebrafish chaperone protein GP96 is required for otolith formation during ear development.
Saulius Sumanas, Jon D Larson, Michele Miller Bever

Dev Biol· September 2003

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Morpholino phosphorodiamidate oligonucleotides in zebrafish: a recipe for functional genomics?
Saulius Sumanas, Jon D Larson

Brief Funct Genomic Proteomic· October 2002

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