Publications by authors named "Jon D Piganelli"

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Islet-intrinsic sex differences in inflammatory signaling contribute to autoimmune diabetes susceptibility.
Kierstin L Webster, Armando A Puente, Jacob R Enriquez, Soumyadeep Sarkar, Ernesto S Nakayasu, Jon D Piganelli

bioRxiv· October 2025

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Dysfunctional β-cell autophagy induces β-cell stress and enhances islet immunogenicity.
Matthew C Austin, Charanya Muralidharan, Saptarshi Roy, Justin J Crowder, Jon D Piganelli

Front Immunol· May 2025

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Engineering sialylation in pigs: A promising strategy for overcoming xenograft rejection and revolutionizing organ transplantation.
Saptarshi Roy, Chaitra Rao, Emily K Sims, Rita Bottino, David K C Cooper, Jon D Piganelli

bioRxiv· May 2025

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Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8 T cell activity and biomarker during the evolution of type 1 diabetes.
Chaitra Rao, Daniel T Cater, Saptarshi Roy, Jerry Xu, Andre G De Oliveira, Jon D Piganelli

Diabetologia· February 2025

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Decoding the immune dance: Unraveling the interplay between beta cells and type 1 diabetes.
Saptarshi Roy, Pravil Pokharel, Jon D Piganelli

Mol Metab· October 2024

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Beta cell extracellular vesicle PD-L1 as a novel regulator of CD8+ T cell activity and biomarker during the evolution of Type 1 Diabetes.
Chaitra Rao, Daniel T Cater, Saptarshi Roy, Jerry Xu, Andre De G Olivera, Jon D Piganelli

bioRxiv· September 2024

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Acinar to β-like cell conversion through inhibition of focal adhesion kinase.
Shakti Dahiya, Mohamed Saleh, Uylissa A Rodriguez, Dhivyaa Rajasundaram, Jorge R Arbujas, Jon D Piganelli

Nat Commun· May 2024

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An orally available cancer drug AZD6738 prevents type 1 diabetes.
Norie Sugitani, Hannah R Mason, Brian T Campfield, Jon D Piganelli

Front Immunol· January 2024

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Epithelial NAD depletion drives mitochondrial dysfunction and contributes to intestinal inflammation.
Elizabeth A Novak, Erin C Crawford, Heather L Mentrup, Brian D Griffith, David M Fletcher, Jon D Piganelli

Front Immunol· September 2023

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Focal adhesion kinase-mediated signaling controls the onset of pancreatic cell differentiation.
Uylissa A Rodriguez, Shakti Dahiya, Michelle L Raymond, Chenxi Gao, Christina P Martins-Cargill, Jon D Piganelli

Development· September 2022

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Editorial: Immunopathology of Type 1 Diabetes.
E Allison Green, Anne C Cooke, Jon D Piganelli, Sarah J Richardson, Li Wen

Front Immunol· April 2022

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Glycolysis Inhibition Induces Functional and Metabolic Exhaustion of CD4 T Cells in Type 1 Diabetes.
Christina P Martins, Lee A New, Erin C O'Connor, Dana M Previte, Kasey R Cargill, Jon D Piganelli

Front Immunol· October 2021

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The Role of β Cell Stress and Neo-Epitopes in the Immunopathology of Type 1 Diabetes.
Jon D Piganelli, Mark J Mamula, Eddie A James

Front Endocrinol (Lausanne)· May 2021

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Auto-antigen and Immunomodulatory Agent-Based Approaches for Antigen-Specific Tolerance in NOD Mice.
Ethan J Bassin, Jon D Piganelli, Steven R Little

Curr Diab Rep· February 2021

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TRI microparticles prevent inflammatory arthritis in a collagen-induced arthritis model.
Ethan J Bassin, Abigail R Buckley, Jon D Piganelli, Steven R Little

PLoS One· November 2020

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T Cell Receptor-Independent, CD31/IL-17A-Driven Inflammatory Axis Shapes Synovitis in Juvenile Idiopathic Arthritis.
Ian D Ferguson, Patricia Griffin, Joshua J Michel, Hiroshi Yano, Sarah L Gaffen, Jon D Piganelli

Front Immunol· October 2019

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A Noncanonical Role for Plasminogen Activator Inhibitor Type 1 in Obesity-Induced Diabetes.
Gina M Coudriet, John Stoops, Anne V Orr, Bharat Bhushan, Kelly Koral, Jon D Piganelli

Am J Pathol· July 2019

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Dietary Cellulose Supplementation Modulates the Immune Response in a Murine Endotoxemia Model.
Valentina Di Caro, Jessica L Cummings, Alicia M Alcamo, Jon D Piganelli, Robert S B Clark

Shock· April 2019

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Lymphocyte Activation Gene-3 Maintains Mitochondrial and Metabolic Quiescence in Naive CD4 T Cells.
Dana M Previte, Christina P Martins, Erin C O'Connor, Meghan L Marre, Gina M Coudriet, Jon D Piganelli

Cell Rep· April 2019

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Calcium/calmodulin-dependent protein kinase IV (CaMKIV) activation contributes to the pathogenesis of experimental colitis via inhibition of intestinal epithelial cell proliferation.
Kellie E Cunningham, Elizabeth A Novak, Garret Vincent, Vei Shaun Siow, Brian D Griffith, Jon D Piganelli

FASEB J· January 2019

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Inflammation-Induced Citrullinated Glucose-Regulated Protein 78 Elicits Immune Responses in Human Type 1 Diabetes.
Mijke Buitinga, Aïsha Callebaut, Fernanda Marques Câmara Sodré, Inne Crèvecoeur, Gabriele Blahnik-Fagan, Jon D Piganelli

Diabetes· November 2018

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Protecting functional β cells with a therapeutic peptide.
Meghan L Marré, Jon D Piganelli, Eddie A James

Ann Transl Med· September 2018

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BMX-001, a novel redox-active metalloporphyrin, improves islet function and engraftment in a murine transplant model.
Antonio Bruni, Andrew R Pepper, Rena L Pawlick, Boris Gala-Lopez, Anissa Gamble, Jon D Piganelli

Am J Transplant· August 2018

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Modifying Enzymes Are Elicited by ER Stress, Generating Epitopes That Are Selectively Recognized by CD4 T Cells in Patients With Type 1 Diabetes.
Meghan L Marre, John W McGinty, I-Ting Chow, Megan E DeNicola, Noah W Beck, Jon D Piganelli

Diabetes· July 2018

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Endogenous Reprogramming of Alpha Cells into Beta Cells, Induced by Viral Gene Therapy, Reverses Autoimmune Diabetes.
Xiangwei Xiao, Ping Guo, Chiyo Shiota, Ting Zhang, Gina M Coudriet, Jon D Piganelli

Cell Stem Cell· January 2018

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