Publications by authors named "Jon D Wright"

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2FA-Platform Generates Dual Fatty Acid-Conjugated GLP-1 Receptor Agonist TE-8105 with Enhanced Diabetes, Obesity, and NASH Efficacy Compared to Semaglutide.
Mun-Teng Wong, Pei-Hsuan Lin, Wei-Chen Lin, Chi-Jiun Peng, Jon D Wright

J Med Chem· March 2025

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PPI-hotspot for detecting protein-protein interaction hot spots from the free protein structure.
Yao Chi Chen, Karen Sargsyan, Jon D Wright, Yu-Hsien Chen, Yi-Shuian Huang

Elife· September 2024

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PPI-Hotspot: Database of Protein-Protein Interaction Hot Spots.
Yao Chi Chen, Yu-Hsien Chen, Jon D Wright, Carmay Lim

J Chem Inf Model· February 2022

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Soluble klotho regulates TRPC6 calcium signaling lipid rafts, independent of the FGFR-FGF23 pathway.
Jon D Wright, Sung-Wan An, Jian Xie, Carmay Lim, Chou-Long Huang

FASEB J· August 2019

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The Zinc Linchpin Motif in the DNA Repair Glycosylase MUTYH: Identifying the Zn Ligands and Roles in Damage Recognition and Repair.
Nicole N Nuñez, Cindy Khuu, C Satheesan Babu, Steve J Bertolani, Anisha N Rajavel, Jon D Wright

J Am Chem Soc· October 2018

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Modeled structural basis for the recognition of α2-3-sialyllactose by soluble Klotho.
Jon D Wright, Sung-Wan An, Jian Xie, Joonho Yoon, Nicole Nischan

FASEB J· August 2017

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Structural and Physical Basis for Anti-IgE Therapy.
Jon D Wright, Hsing-Mao Chu, Chun-Hsiang Huang, Che Ma, Tse Wen Chang

Sci Rep· June 2015

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Identifying RNA-binding residues based on evolutionary conserved structural and energetic features.
Yao Chi Chen, Karen Sargsyan, Jon D Wright, Yi-Shuian Huang, Carmay Lim

Nucleic Acids Res· February 2014

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Protein-Protein Docking Using EMAP in CHARMM and Support Vector Machine: Application to Ab/Ag Complexes.
Jon D Wright, Karen Sargsyan, Xiongwu Wu, Bernard R Brooks, Carmay Lim

J Chem Theory Comput· September 2013

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DR_bind: a web server for predicting DNA-binding residues from the protein structure based on electrostatics, evolution and geometry.
Yao Chi Chen, Jon D Wright, Carmay Lim

Nucleic Acids Res· July 2012

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Redesign of high-affinity nonspecific nucleases with altered sequence preference.
Yi-Ting Wang, Jon D Wright, Lyudmila G Doudeva, Hua-Ci Jhang, Carmay Lim

J Am Chem Soc· December 2009

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Combined experimental and theoretical study of long-range interactions modulating dimerization and activity of yeast geranylgeranyl diphosphate synthase.
Chia-Hsiang Lo, Ying-Hsuan Chang, Jon D Wright, Shih-Hsun Chen, Daphne Kan

J Am Chem Soc· March 2009

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Mechanism of DNA-binding loss upon single-point mutation in p53.
Jon D Wright, Carmay Lim

J Biosci· August 2007

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Factors governing loss and rescue of DNA binding upon single and double mutations in the p53 core domain.
Jon D Wright, Sergey Yu Noskov, Carmay Lim

Nucleic Acids Res· April 2002

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