Publications by authors named "Jon G Mabley"

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Divergent effects of HIV reverse transcriptase inhibitors on pancreatic beta-cell function and survival: Potential role of oxidative stress and mitochondrial dysfunction.
Soulef Chahinez Maandi, Meriem Tinhinane Maandi, Anneka Patel, Rían W Manville, Jon Gunnarsson Mabley

Life Sci· April 2022

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Effect of the Anti-retroviral Drugs Efavirenz, Tenofovir and Emtricitabine on Endothelial Cell Function: Role of PARP.
Mary Faltz, Hild Bergin, Elly Pilavachi, Guy Grimwade, Jon G Mabley

Cardiovasc Toxicol· October 2017

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Lipotoxicity in renal proximal tubular cells: relationship between endoplasmic reticulum stress and oxidative stress pathways.
Elias Katsoulieris, Jon G Mabley, Mohamed Samai, Martyn A Sharpe, Irene C Green

Free Radic Biol Med· June 2010

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alpha-Linolenic acid protects renal cells against palmitic acid lipotoxicity via inhibition of endoplasmic reticulum stress.
Elias Katsoulieris, Jon G Mabley, Mohamed Samai, Irene C Green, Prabal K Chatterjee

Eur J Pharmacol· November 2009

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PCB-induced endothelial cell dysfunction: role of poly(ADP-ribose) polymerase.
Simon G Helyar, Bella Patel, Kevin Headington, Mary El Assal, Prabal K Chatterjee, Jon G Mabley

Biochem Pharmacol· October 2009

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The novel inosine analogue INO-2002 exerts an anti-inflammatory effect in a murine model of acute lung injury.
Jon G Mabley, Pal Pacher, Kanneganti G K Murthy, William Williams, Garry J Southan

Shock· September 2009

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Activation of the cholinergic antiinflammatory pathway reduces ricin-induced mortality and organ failure in mice.
Jon G Mabley, Pal Pacher, Csaba Szabo

Mol Med· September 2009

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Xanthine oxidase inhibitor allopurinol attenuates the development of diabetic cardiomyopathy.
Mohanraj Rajesh, Partha Mukhopadhyay, Sándor Bátkai, Bani Mukhopadhyay, Vivek Patel, Jon G Mabley

J Cell Mol Med· August 2009

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The novel inosine analogue, INO-2002, protects against diabetes development in multiple low-dose streptozotocin and non-obese diabetic mouse models of type I diabetes.
Jon G Mabley, Pal Pacher, Kanneganti G K Murthy, William Williams, Garry J Southan

J Endocrinol· September 2008

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Adenosine receptor activation ameliorates type 1 diabetes.
Zoltán H Németh, David Bleich, Balázs Csóka, Pál Pacher, Jon G Mabley

FASEB J· August 2007

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Inhibition of poly(adenosine diphosphate-ribose) polymerase by the active form of vitamin D.
Jon G Mabley, Rebecca Wallace, Pál Pacher, Kanneganti Murphy, Csaba Szabó

Int J Mol Med· June 2007

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Beneficial effects of a novel ultrapotent poly(ADP-ribose) polymerase inhibitor in murine models of heart failure.
Pál Pacher, Lucas Liaudet, Jon G Mabley, Attila Cziráki, György Haskó

Int J Mol Med· February 2006

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Gender differences in the endotoxin-induced inflammatory and vascular responses: potential role of poly(ADP-ribose) polymerase activation.
Jon G Mabley, Eszter M Horváth, Kanneganti G K Murthy, Zsuzsanna Zsengellér, Anne Vaslin

J Pharmacol Exp Ther· November 2005

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Angiotensin II-mediated endothelial dysfunction: role of poly(ADP-ribose) polymerase activation.
Csaba Szabó, Pál Pacher, Zsuzsanna Zsengellér, Anne Vaslin, Katalin Komjáti, Jon G Mabley

Mol Med· October 2005

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Discovery of potent poly(ADP-ribose) polymerase-1 inhibitors from the modification of indeno[1,2-c]isoquinolinone.
Prakash G Jagtap, Erkan Baloglu, Garry J Southan, Jon G Mabley, Hongshan Li

J Med Chem· August 2005

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Role of nitrosative stress and poly(ADP-ribose) polymerase activation in diabetic vascular dysfunction.
Jon G Mabley, Francisco Garcia Soriano

Curr Vasc Pharmacol· July 2005

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Role of nitrosative stress and peroxynitrite in the pathogenesis of diabetic complications. Emerging new therapeutical strategies.
Pál Pacher, Irina G Obrosova, Jon G Mabley, Csaba Szabó

Curr Med Chem· May 2005

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Role for nitrosative stress in diabetic neuropathy: evidence from studies with a peroxynitrite decomposition catalyst.
Irina G Obrosova, Jon G Mabley, Zsuzsanna Zsengellér, Tamara Charniauskaya, Omorodola I Abatan

FASEB J· March 2005

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Potential role for 8-oxoguanine DNA glycosylase in regulating inflammation.
Jon G Mabley, Pál Pacher, Amitabha Deb, Rebecca Wallace, Rhoderick H Elder

FASEB J· February 2005

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A new, potent poly(ADP-ribose) polymerase inhibitor improves cardiac and vascular dysfunction associated with advanced aging.
Pál Pacher, Anne Vaslin, Rita Benko, Jon G Mabley, Lucas Liaudet

J Pharmacol Exp Ther· November 2004

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Left ventricular pressure-volume relationship in a rat model of advanced aging-associated heart failure.
Pál Pacher, Jon G Mabley, Lucas Liaudet, Oleg V Evgenov, Anita Marton

Am J Physiol Heart Circ Physiol· November 2004

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The therapeutic effects of PJ34 [N-(6-oxo-5,6-dihydrophenanthridin-2-yl)-N,N-dimethylacetamide.HCl], a selective inhibitor of poly(ADP-ribose) polymerase, in experimental allergic encephalomyelitis are associated with immunomodulation.
Gwen S Scott, Rhonda B Kean, Tatiana Mikheeva, Marzena J Fabis, Jon G Mabley

J Pharmacol Exp Ther· September 2004

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Suppression of intestinal polyposis in Apcmin/+ mice by targeting the nitric oxide or poly(ADP-ribose) pathways.
Jon G Mabley, Pál Pacher, Peter Bai, Rebecca Wallace, Sunali Goonesekera

Mutat Res· April 2004

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Effects of poly(ADP-ribose) polymerase inhibition on inflammatory cell migration in a murine model of asthma.
László Virág, Péter Bai, István Bak, Pál Pacher, Jon G Mabley

Med Sci Monit· March 2004

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The combined inducible nitric oxide synthase inhibitor and free radical scavenger guanidinoethyldisulfide prevents multiple low-dose streptozotocin-induced diabetes in vivo and interleukin-1beta-induced suppression of islet insulin secretion in vitro.
Jon G Mabley, Gary J Southan, Andrew L Salzman, Csaba Szabó

Pancreas· March 2004

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