Publications by authors named "Jon Lorsch"

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Applied research won't flourish without basic science.
Jon R Lorsch, Lawrence A Tabak, Monica M Bertagnolli

Elife· September 2024

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NIGMS Sandbox: a learning platform toward democratizing cloud computing for biomedical research.
Ming Lei, Lakshmi K Matukumalli, Krishan Arora, Nick Weber, Rachel Malashock, Jon Lorsch

Brief Bioinform· July 2024

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Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system.
Fujun Zhou, Julie M Bocetti, Meizhen Hou, Daoming Qin, Alan G Hinnebusch, Jon R Lorsch

Elife· April 2024

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Transcriptome-wide analysis of the function of Ded1 in translation preinitiation complex assembly in a reconstituted in vitro system.
Fujun Zhou, Julie M Bocetti, Meizhen Hou, Daoming Qin, Alan G Hinnebusch, Jon R Lorsch

bioRxiv· February 2024

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The All of Us Research Program is an opportunity to enhance the diversity of US biomedical research.
Diana W Bianchi, Patricia Flatley Brennan, Michael F Chiang, Lindsey A Criswell, Rena N D'Souza, Jon R Lorsch

Nat Med· February 2024

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Increasing Clinician-Scientist Workforce Diversity through the National Institute of General Medical Sciences' Medical Scientist Training Program.
Alison E Gammie, Travis F Dorsey, Sabrina F Epou, Andrew C Miklos, Jon R Lorsch

ATS Sch· October 2022

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Affirming NIH's commitment to addressing structural racism in the biomedical research enterprise.
Francis S Collins, Amy Bany Adams, Courtney Aklin, Trevor K Archer, Marie A Bernard, Jon Lorsch

Cell· June 2021

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Developing a culture of safety in biomedical research training.
Michelle R Bond, Alison E Gammie, Jon R Lorsch

Mol Biol Cell· October 2020

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Distinct interactions of eIF4A and eIF4E with RNA helicase Ded1 stimulate translation in vivo.
Suna Gulay, Neha Gupta, Jon R Lorsch, Alan G Hinnebusch

Elife· May 2020

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eIF1 discriminates against suboptimal initiation sites to prevent excessive uORF translation genome-wide.
Fujun Zhou, Hongen Zhang, Shardul D Kulkarni, Jon R Lorsch, Alan G Hinnebusch

RNA· April 2020

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Temperature-dependent regulation of upstream open reading frame translation in S. cerevisiae.
Shardul D Kulkarni, Fujun Zhou, Neelam Dabas Sen, Hongen Zhang, Alan G Hinnebusch, Jon R Lorsch

BMC Biol· December 2019

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Functional interplay between DEAD-box RNA helicases Ded1 and Dbp1 in preinitiation complex attachment and scanning on structured mRNAs in vivo.
Neelam Dabas Sen, Neha Gupta, Stuart K Archer, Thomas Preiss, Jon R Lorsch

Nucleic Acids Res· September 2019

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Translational initiation factor eIF5 replaces eIF1 on the 40S ribosomal subunit to promote start-codon recognition.
Jose Luis Llácer, Tanweer Hussain, Adesh K Saini, Jagpreet Singh Nanda, Sukhvir Kaur, Jon R Lorsch

Elife· November 2018

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Yeast Ded1 promotes 48S translation pre-initiation complex assembly in an mRNA-specific and eIF4F-dependent manner.
Neha Gupta, Jon R Lorsch, Alan G Hinnebusch

Elife· October 2018

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eIF1A residues implicated in cancer stabilize translation preinitiation complexes and favor suboptimal initiation sites in yeast.
Pilar Martin-Marcos, Fujun Zhou, Charm Karunasiri, Fan Zhang, Jinsheng Dong, Jon R Lorsch

Elife· December 2017

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Yeast eIF4A enhances recruitment of mRNAs regardless of their structural complexity.
Paul Yourik, Colin Echeverría Aitken, Fujun Zhou, Neha Gupta, Alan G Hinnebusch, Jon R Lorsch

Elife· November 2017

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Rps3/uS3 promotes mRNA binding at the 40S ribosome entry channel and stabilizes preinitiation complexes at start codons.
Jinsheng Dong, Colin Echeverría Aitken, Anil Thakur, Byung-Sik Shin, Jon R Lorsch

Proc Natl Acad Sci U S A· March 2017

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Active yeast ribosome preparation using monolithic anion exchange chromatography.
Antonio M Munoz, Paul Yourik, Vaishnavi Rajagopal, Jagpreet S Nanda, Jon R Lorsch

RNA Biol· February 2017

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Eukaryotic translation initiation factor 3 plays distinct roles at the mRNA entry and exit channels of the ribosomal preinitiation complex.
Colin Echeverría Aitken, Petra Beznosková, Vladislava Vlčkova, Wen-Ling Chiu, Fujun Zhou, Jon R Lorsch

Elife· October 2016

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Protein Affinity Purification using Intein/Chitin Binding Protein Tags.
Sarah F Mitchell, Jon R Lorsch

Methods Enzymol· March 2016

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Preface. Laboratory Methods in Enzymology: Protein Part D.
Jon R Lorsch

Methods Enzymol· March 2016

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Basic science: Bedrock of progress.
Francis S Collins, James M Anderson, Christopher P Austin, James F Battey, Linda S Birnbaum, Jon R Lorsch

Science· March 2016

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Perspective: Sustaining the big-data ecosystem.
Philip E Bourne, Jon R Lorsch, Eric D Green

Nature· November 2015

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Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex.
Jose L Llácer, Tanweer Hussain, Laura Marler, Colin Echeverría Aitken, Anil Thakur, Jon R Lorsch

Mol Cell· August 2015

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Eukaryotic translation initiation factor eIF5 promotes the accuracy of start codon recognition by regulating Pi release and conformational transitions of the preinitiation complex.
Adesh K Saini, Jagpreet S Nanda, Pilar Martin-Marcos, Jinsheng Dong, Fan Zhang, Jon R Lorsch

Nucleic Acids Res· June 2015

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