Publications by authors named "Jon Mirsalis"

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Potent Acridone Antimalarial against All Three Life Stages of .
Papireddy Kancharla, Rozalia A Dodean, Yuexin Li, Xiaowei Zhang, Sean Kelly, Jon Mirsalis

Res Sq· June 2025

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3D Spheroids of Human Primary Urine-Derived Stem Cells in the Assessment of Drug-Induced Mitochondrial Toxicity.
Huifen Ding, Kalyani Jambunathan, Guochun Jiang, David M Margolis, Iris Leng, Jon Mirsalis

Pharmaceutics· May 2022

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Correction to: Enhancement of sensitivity and quantification quality in the LC-MS/MS measurement of large biomolecules with sum of MRM (SMRM).
Liang Tang, Robert R Swezey, Carol E Green, Jon C Mirsalis

Anal Bioanal Chem· March 2022

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Enhancement of sensitivity and quantification quality in the LC-MS/MS measurement of large biomolecules with sum of MRM (SMRM).
Liang Tang, Robert R Swezey, Carol E Green, Jon C Mirsalis

Anal Bioanal Chem· February 2022

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Formulation, Stability, Pharmacokinetic, and Modeling Studies for Tests of Synergistic Combinations of Orally Available Approved Drugs against Ebola Virus In Vivo.
Courtney L Finch, Julie Dyall, Shuang Xu, Elizabeth A Nelson, Elena Postnikova, Jon C Mirsalis

Microorganisms· March 2021

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Selecting an anti-malarial clinical candidate from two potent dihydroisoquinolones.
Yizhe Chen, Fangyi Zhu, Jared Hammill, Gloria Holbrook, Lei Yang, Jon C Mirsalis

Malar J· February 2021

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In Vivo Activity of Amodiaquine against Ebola Virus Infection.
Lisa Evans DeWald, Joshua C Johnson, Dawn M Gerhardt, Lisa M Torzewski, Elena Postnikova, Jon C Mirsalis

Sci Rep· December 2019

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Increased stress associated with head-out plethysmography testing can exacerbate respiratory effects and lead to mortality in rats.
James J Lynch, Emilie Rossignol, Joerg J Moehrle, Terry R Van Vleet, Kennan C Marsh, Jon Mirsalis

J Pharmacol Toxicol Methods· May 2019

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In Vitro and In Vivo Activity of Amiodarone Against Ebola Virus.
Julie Dyall, Joshua C Johnson, Brit J Hart, Elena Postnikova, Yu Cong, Jon C Mirsalis

J Infect Dis· November 2018

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Structure-based lead optimization to improve antiviral potency and ADMET properties of phenyl-1H-pyrrole-carboxamide entry inhibitors targeted to HIV-1 gp120.
Francesca Curreli, Dmitry S Belov, Young Do Kwon, Ranjith Ramesh, Anna M Furimsky, Jon C Mirsalis

Eur J Med Chem· June 2018

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Efficacy of Tilorone Dihydrochloride against Ebola Virus Infection.
Sean Ekins, Mary A Lingerfelt, Jason E Comer, Alexander N Freiberg, Jon C Mirsalis

Antimicrob Agents Chemother· February 2018

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Evaluation of the Activity of Lamivudine and Zidovudine against Ebola Virus.
Yu Cong, Julie Dyall, Brit J Hart, Lisa Evans DeWald, Joshua C Johnson, Jon C Mirsalis

PLoS One· September 2017

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Evaluation of Cardiac Toxicity Biomarkers in Rats from Different Laboratories.
Kyuri Kim, Naseem Chini, David G Fairchild, Steven K Engle, William J Reagan, Jon C Mirsalis

Toxicol Pathol· December 2016

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Preclinical studies on the pharmacokinetics, safety, and toxicology of oxfendazole: toward first in human studies.
Ellen E Codd, Hanna H Ng, Claire McFarlane, Edward S Riccio, Rupa Doppalapudi, Jon C Mirsalis

Int J Toxicol· April 2016

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New candidate biomarkers in the female genital tract to evaluate microbicide toxicity.
Scott Fields, Benben Song, Bareza Rasoul, Julie Fong, Melissa G Works, Jon Mirsalis

PLoS One· December 2015

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Preclinical Evaluations To Identify Optimal Linezolid Regimens for Tuberculosis Therapy.
Ashley N Brown, George L Drusano, Jonathan R Adams, Jaime L Rodriquez, Kalyani Jambunathan, Jon C Mirsalis

mBio· November 2015

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Tenofovir disoproxil fumarate: toxicity, toxicokinetics, and toxicogenomics analysis after 13 weeks of oral administration in mice.
Hanna H Ng, Howard Stock, Linda Rausch, Deborah Bunin, Abraham Wang, Jon C Mirsalis

Int J Toxicol· October 2015

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A long-duration dihydroorotate dehydrogenase inhibitor (DSM265) for prevention and treatment of malaria.
Margaret A Phillips, Julie Lotharius, Kennan Marsh, John White, Anthony Dayan, Jon Mirsalis

Sci Transl Med· July 2015

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Quantitative proteomics for cardiac biomarker discovery using isoproterenol-treated nonhuman primates.
Benben Song, Yashu Liu, Toufan Parman, Shufeng Liu, Jennifer K Miller, Jon Mirsalis

J Proteome Res· December 2014

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(+)-SJ733, a clinical candidate for malaria that acts through ATP4 to induce rapid host-mediated clearance of Plasmodium.
María Belén Jiménez-Díaz, Daniel Ebert, Yandira Salinas, Anupam Pradhan, Adele M Lehane, Jon C Mirsalis

Proc Natl Acad Sci U S A· December 2014

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Pharmacokinetics and dose-range finding toxicity of a novel anti-HIV active integrase inhibitor.
Vasu Nair, Maurice Okello, Sanjay Mishra, Jon Mirsalis, Kathleen O'Loughlin

Antiviral Res· August 2014

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Evaluation of Antitrypanosomal Dihydroquinolines for Hepatotoxicity, Mutagenicity, and Methemoglobin Formation In Vitro.
Karl A Werbovetz, Edward S Riccio, Anna Furimsky, Julian V Richard, Shanshan He, Jon Mirsalis

Int J Toxicol· July 2014

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Serum biomarkers reveal long-term cardiac injury in isoproterenol-treated African green monkeys.
Yashu Liu, Toufan Parman, Bridget Schneider, Benben Song, Amit K Galande, Jon Mirsalis

J Proteome Res· April 2013

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Evaluation of arylimidamides DB1955 and DB1960 as candidates against visceral leishmaniasis and Chagas' disease: in vivo efficacy, acute toxicity, pharmacokinetics, and toxicology studies.
Xiaohua Zhu, Qiang Liu, Sihyung Yang, Toufan Parman, Carol E Green, Jon C Mirsalis

Antimicrob Agents Chemother· July 2012

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Lead optimization of antimalarial propafenone analogues.
David Lowes, Anupam Pradhan, Lalitha V Iyer, Toufan Parman, Jason Gow, Jon Mirsalis

J Med Chem· July 2012

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