Publications by authors named "Jon Obst"

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Inhibitors of the transactivation domain of androgen receptor as a therapy for prostate cancer.
Jon K Obst, Amy H Tien, Josie C Setiawan, Lauren F Deneault, Marianne D Sadar

Steroids· October 2024

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Rational optimization of a transcription factor activation domain inhibitor.
Shaon Basu, Paula Martínez-Cristóbal, Marta Frigolé-Vivas, Mireia Pesarrodona, Michael Lewis, Jon K Obst

Nat Struct Mol Biol· December 2023

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Differential Gene Expression Profiles between N-Terminal Domain and Ligand-Binding Domain Inhibitors of Androgen Receptor Reveal Ralaniten Induction of Metallothionein by a Mechanism Dependent on MTF1.
Jon K Obst, Nasrin R Mawji, Simon J L Teskey, Jun Wang, Marianne D Sadar

Cancers (Basel)· January 2022

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Ralaniten Sensitizes Enzalutamide-Resistant Prostate Cancer to Ionizing Radiation in Prostate Cancer Cells that Express Androgen Receptor Splice Variants.
Carmen A Banuelos, Yusuke Ito, Jon K Obst, Nasrin R Mawji, Jun Wang

Cancers (Basel)· July 2020

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Revealing Metabolic Liabilities of Ralaniten To Enhance Novel Androgen Receptor Targeted Therapies.
Jon K Obst, Jun Wang, Kunzhong Jian, David E Williams, Amy H Tien

ACS Pharmacol Transl Sci· December 2019

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Directing abiraterone metabolism: balancing the scales between clinical relevance and experimental observation.
Jon K Obst, Marianne D Sadar

Transl Cancer Res· September 2016

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Conditional protein splicing of α-sarcin in live cells.
Spencer C Alford, Connor O'Sullivan, Jon Obst, Jennifer Christie, Perry L Howard

Mol Biosyst· April 2014

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