Publications by authors named "Jon Oyer"

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Real-world clinical multi-omics analyses reveal bifurcation of ER-independent and ER-dependent drug resistance to CDK4/6 inhibitors.
Zhengyan Kan, Ji Wen, Vinicius Bonato, Jennifer Webster, Wenjing Yang, Jon Oyer

Nat Commun· January 2025

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Use of the dTAG system in vivo to degrade CDK2 and CDK5 in adult mice and explore potential safety liabilities.
Paul Yenerall, Tae Sung, Kiran Palyada, Jessie Qian, Seda Arat, Jon Oyer

Toxicol Sci· June 2023

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PARP1-SNAI2 transcription axis drives resistance to PARP inhibitor, Talazoparib.
Xia Ding, Zhou Zhu, John Lapek, Elizabeth A McMillan, Alexander Zhang, Jon Oyer

Sci Rep· July 2022

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PRC2 Inhibitors Overcome Glucocorticoid Resistance Driven by Mutation in Pediatric Acute Lymphoblastic Leukemia.
Jianping Li, Julia Hlavka-Zhang, Jonathan H Shrimp, Crissandra Piper, Daphne Dupéré-Richér, Jon A Oyer

Cancer Discov· January 2022

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Fluorophosphonate-Based Degrader Identifies Degradable Serine Hydrolases by Quantitative Proteomics.
S Denise Field, Wankyu Lee, Jason K Dutra, Finley Scott F Serneo, Jon Oyer

Chembiochem· October 2020

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A Mutation in Histone H2B Represents a New Class of Oncogenic Driver.
Richard L Bennett, Aditya Bele, Eliza C Small, Christine M Will, Behnam Nabet, Jon A Oyer

Cancer Discov· October 2019

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An activating mutation of the NSD2 histone methyltransferase drives oncogenic reprogramming in acute lymphocytic leukemia.
Alok Swaroop, Jon A Oyer, Christine M Will, Xiaoxiao Huang, Wenbo Yu

Oncogene· January 2019

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Emerging Approaches for the Identification of Protein Targets of Small Molecules - A Practitioners' Perspective.
Kenneth M Comess, Shaun M McLoughlin, Jon A Oyer, Paul L Richardson, Henning Stöckmann

J Med Chem· October 2018

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UTX/KDM6A Loss Enhances the Malignant Phenotype of Multiple Myeloma and Sensitizes Cells to EZH2 inhibition.
Teresa Ezponda, Daphné Dupéré-Richer, Christine M Will, Eliza C Small, Nobish Varghese, Jon Oyer

Cell Rep· October 2017

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C-terminal domain small phosphatase 1 and MAP kinase reciprocally control REST stability and neuronal differentiation.
Edmund Nesti, Glen M Corson, Maxwell McCleskey, Jon A Oyer, Gail Mandel

Proc Natl Acad Sci U S A· September 2014

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Polycomb- and REST-associated histone deacetylases are independent pathways toward a mature neuronal phenotype.
James C McGann, Jon A Oyer, Saurabh Garg, Huilan Yao, Jun Liu

Elife· September 2014

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Cardiovascular and systemic microvascular effects of anti-vascular endothelial growth factor therapy for cancer.
J Todd Belcik, Yue Qi, Beat A Kaufmann, Aris Xie, Sherry Bullens, Jon A Oyer

J Am Coll Cardiol· August 2012

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Aberrantly silenced promoters retain a persistent memory of the silenced state after long-term reactivation.
Jon A Oyer, Phillip A Yates, Sarah Godsey, Mitchell S Turker

Mutat Res· January 2011

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Aberrant epigenetic silencing is triggered by a transient reduction in gene expression.
Jon A Oyer, Adrian Chu, Sukhmani Brar, Mitchell S Turker

PLoS One· May 2009

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