Publications by authors named "Jonathan A Phillips"

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Sensorineural correlates of failed functional recovery after natural regeneration of vestibular hair cells in adult mice.
Emmanuel J Jáuregui, Kelli L Scheinman, Ingrid K Bibriesca Mejia, Lindsay Pruett, Hannah Zaini, Jonathan A Phillips, James O Phillips

Front Neurol· March 2024

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Clinical Pharmacology and Translational Considerations in the Development of CRISPR-Based Therapies.
Ahmed M Abdelhady, Jonathan A Phillips, Yuanxin Xu, Mark Stroh

Clin Pharmacol Ther· September 2023

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Mode of action and human relevance assessment of male CD-1 mouse renal adenocarcinoma associated with lifetime exposure to empagliflozin.
Jonathan A Phillips, Mitchell E Taub, Matthew S Bogdanffy, Jing Yuan, Brian Knight

J Appl Toxicol· October 2022

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Microphysiological systems for ADME-related applications: current status and recommendations for system development and characterization.
Stephen Fowler, Wen Li Kelly Chen, David B Duignan, Anshul Gupta, Niresh Hariparsad, Jonathan A Phillips

Lab Chip· February 2020

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A pharmaceutical industry perspective on microphysiological kidney systems for evaluation of safety for new therapies.
Jonathan A Phillips, Taraka Sai Pavan Grandhi, Myrtle Davis, Jean-Charles Gautier, Niresh Hariparsad

Lab Chip· February 2020

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Pathogenesis of Renal Injury and Gene Expression Changes in the Male CD-1 Mouse Associated with Exposure to Empagliflozin.
Brian Knight, Jing Yuan, Sally Koegler, Parimal Pande, Jennifer Hall, Jonathan A Phillips

Toxicol Pathol· August 2018

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A Predominant Oxidative Renal Metabolite of Empagliflozin in Male Mice Is Cytotoxic in Mouse Renal Tubular Cells but not Genotoxic.
James D Smith, Zimei Huang, Patricia A Escobar, Pamela Foppiano, Hlaing Maw, Jonathan A Phillips

Int J Toxicol· July 2018

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Navigating tissue chips from development to dissemination: A pharmaceutical industry perspective.
Lorna Ewart, Kristin Fabre, Ananthsrinivas Chakilam, Yvonne Dragan, David B Duignan, Jonathan A Phillips

Exp Biol Med (Maywood)· October 2017

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A Multiplatform Approach for the Discovery of Novel Drug-Induced Kidney Injury Biomarkers.
Liuxi Chen, James Smith, Jaromir Mikl, Ryan Fryer, Frank Pack, Jonathan A Phillips

Chem Res Toxicol· October 2017

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Identification of sperm mRNA biomarkers associated with testis injury during preclinical testing of pharmaceutical compounds.
Edward Dere, Daniel J Spade, Susan J Hall, Aimee Altemus, James D Smith, Jonathan A Phillips

Toxicol Appl Pharmacol· April 2017

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Net Reclassification Index and Integrated Discrimination Index Are Not Appropriate for Testing Whether a Biomarker Improves Predictive Performance.
Peter M Burch, Warren E Glaab, Daniel J Holder, Jonathan A Phillips, John-Michael Sauer

Toxicol Sci· March 2017

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Rat Urinary Osteopontin and Neutrophil Gelatinase-Associated Lipocalin Improve Certainty of Detecting Drug-Induced Kidney Injury.
Jonathan A Phillips, Daniel J Holder, Daniela Ennulat, Jean-Charles Gautier, John-Michael Sauer

Toxicol Sci· June 2016

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Assessment of inhibin B as a biomarker of testicular injury following administration of carbendazim, cetrorelix, or 1,2-dibromo-3-chloropropane in Wistar han rats.
Jeffrey S Moffit, Leah S Her, Anthony M Mineo, Brian L Knight, Jonathan A Phillips

Birth Defects Res B Dev Reprod Toxicol· February 2013

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Towards consensus practices to qualify safety biomarkers for use in early drug development.
Frank D Sistare, Frank Dieterle, Sean Troth, Daniel J Holder, David Gerhold, Jonathan A Phillips

Nat Biotechnol· May 2010

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Renal biomarker qualification submission: a dialog between the FDA-EMEA and Predictive Safety Testing Consortium.
Frank Dieterle, Frank Sistare, Federico Goodsaid, Marisa Papaluca, Josef S Ozer, Jonathan A Phillips

Nat Biotechnol· May 2010

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Role for beta1 integrins in cortical osteocytes during acute musculoskeletal disuse.
Jonathan A Phillips, Eduardo A C Almeida, Esther L Hill, J Ignacio Aguirre, Mercedes F Rivera

Matrix Biol· September 2008

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Collagen gel contraction assay.
Peter Ngo, Punitha Ramalingam, Jonathan A Phillips, Glenn T Furuta

Methods Mol Biol· October 2006

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Matrix metalloproteinase activity synergizes with alpha2beta1 integrins to enhance collagen remodeling.
Jonathan A Phillips, Lawrence J Bonassar

Exp Cell Res· October 2005

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Fibroblasts regulate contractile force independent of MMP activity in 3D-collagen.
Jonathan A Phillips, Charles A Vacanti, Lawrence J Bonassar

Biochem Biophys Res Commun· December 2003

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