Publications by authors named "Jonathan Axelrod"

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Blockade of Interleukin-6 Trans-signaling in the Presence of Certain Gut Microbiota Induces Mature-onset Obesity in Mice.
Tali Lanton, Dana Eidelshtein, Jacob Rachmilewitz, Rinat Abramovitch, Orit Pappo, Jonathan H Axelrod

Gastro Hep Adv· December 2025

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Combined hepatocellular-cholangiocarcinoma derives from liver progenitor cells and depends on senescence and IL-6 trans-signaling.
Nofar Rosenberg, Matthias Van Haele, Tali Lanton, Neta Brashi, Zohar Bromberg, Jonathan H Axelrod

J Hepatol· December 2022

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Single-cell transcriptomics reveals a senescence-associated IL-6/CCR6 axis driving radiodermatitis.
Mor Paldor, Orr Levkovitch-Siany, Dana Eidelshtein, Revital Adar, Claes D Enk, Jonathan H Axelrod

EMBO Mol Med· August 2022

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Multiple Roles of IL6 in Hepatic Injury, Steatosis, and Senescence Aggregate to Suppress Tumorigenesis.
Anat Shriki, Tali Lanton, Amir Sonnenblick, Orr Levkovitch-Siany, Dana Eidelshtein, Jonathan H Axelrod

Cancer Res· September 2021

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Hepatic Inflammation Confers Protective Immunity Against Liver Stages of Malaria Parasite.
Morgane Grand, Mishelle Waqasi, Claudia Demarta-Gatsi, Yu Wei, Roger Peronet, Jonathan Axelrod

Front Immunol· June 2021

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Hyper-Interleukin-6 Protects Against Renal Ischemic-Reperfusion Injury-A Mouse Model.
Mohammad Zuaiter, Jonathan H Axelrod, Galina Pizov, Ofer N Gofrit

Front Surg· May 2021

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The pro-oncogenic effect of the lncRNA H19 in the development of chronic inflammation-mediated hepatocellular carcinoma.
Lika Gamaev, Lina Mizrahi, Tomer Friehmann, Nofar Rosenberg, Orit Pappo, Jonathan H Axelrod

Oncogene· January 2021

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Agonist of RORA Attenuates Nonalcoholic Fatty Liver Progression in Mice via Up-regulation of MicroRNA 122.
Chofit Chai, Bryan Cox, Dayana Yaish, Devora Gross, Nofar Rosenberg, Jonathan Axelrod

Gastroenterology· September 2020

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The glutathione peroxidase 8 (GPX8)/IL-6/STAT3 axis is essential in maintaining an aggressive breast cancer phenotype.
Anees Khatib, Balakrishnan Solaimuthu, Michal Ben Yosef, Areej Abu Rmaileh, Mayur Tanna, Jonathan H Axelrod

Proc Natl Acad Sci U S A· September 2020

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Interleukin-6 contributes to the increase in fibroblast growth factor 23 expression in acute and chronic kidney disease.
Karina Durlacher-Betzer, Alia Hassan, Ronen Levi, Jonathan Axelrod, Justin Silver

Kidney Int· August 2018

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A Protective Function of IL-22BP in Ischemia Reperfusion and Acetaminophen-Induced Liver Injury.
Dörte Kleinschmidt, Anastasios D Giannou, Heather M McGee, Jan Kempski, Babett Steglich, Jonathan H Axelrod

J Immunol· December 2017

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Split Protein-Ligation Generates Active IL-6-Type Hyper-Cytokines from Inactive Precursors.
Jens M Moll, Melanie Wehmöller, Nils C Frank, Lisa Homey, Paul Baran, Jonathan H Axelrod

ACS Synth Biol· December 2017

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Interleukin 6-dependent genomic instability heralds accelerated carcinogenesis following liver regeneration on a background of chronic hepatitis.
Tali Lanton, Anat Shriki, Yael Nechemia-Arbely, Rinat Abramovitch, Orr Levkovitch, Jonathan H Axelrod

Hepatology· May 2017

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Radiation-Induced Loss of Salivary Gland Function Is Driven by Cellular Senescence and Prevented by IL6 Modulation.
Yitzhak Marmary, Revital Adar, Svetlana Gaska, Annette Wygoda, Alexander Maly, Jonathan H Axelrod

Cancer Res· March 2016

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Sorafenib treatment during partial hepatectomy reduces tumorgenesis in an inflammation-associated liver cancer model.
Tamar Zahavi, Tali Lanton, Mali Salmon Divon, Asher Salmon, Tamar Peretz, Jonathan H Axelrod

Oncotarget· January 2016

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Endothelin-converting enzyme is a plausible target gene for hypoxia-inducible factor.
Mogher Khamaisi, Hala Toukan, Jonathan H Axelrod, Christian Rosenberger, Galia Skarzinski

Kidney Int· April 2015

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Assessment with unenhanced MRI techniques of renal morphology and hemodynamic changes during acute kidney injury and chronic kidney disease in mice.
Zohar Milman, Jonathan H Axelrod, Samuel N Heyman, Nathalie Nachmansson, Rinat Abramovitch

Am J Nephrol· December 2014

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Natural killer cell-dependent anti-fibrotic pathway in liver injury via Toll-like receptor-9.
Lina Abu-Tair, Jonathan H Axelrod, Sarit Doron, Yossi Ovadya, Valery Krizhanovsky

PLoS One· September 2014

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Inflammation-induced hepatocellular carcinoma is dependent on CCR5 in mice.
Neta Barashi, Ido D Weiss, Ori Wald, Hanna Wald, Katia Beider, Jonathan Axelrod

Hepatology· September 2013

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Hemodynamic response magnetic resonance imaging: application for renal hemodynamic characterization.
Zohar Milman, Samuel N Heyman, Nathalie Corchia, Yifat Edrei, Jonathan H Axelrod

Nephrol Dial Transplant· May 2013

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In vivo evidence suggesting reciprocal renal hypoxia-inducible factor-1 upregulation and signal transducer and activator of transcription 3 activation in response to hypoxic and non-hypoxic stimuli.
Yael Nechemia-Arbely, Mogher Khamaisi, Christian Rosenberger, Robert Koesters, Ahuva Shina, Jonathan H Axelrod

Clin Exp Pharmacol Physiol· April 2013

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Tumor STAT3 tyrosine phosphorylation status, as a predictor of benefit from adjuvant chemotherapy for breast cancer.
Amir Sonnenblick, Beatrice Uziely, Hovav Nechushtan, Luna Kadouri, Eithan Galun, Jonathan H Axelrod

Breast Cancer Res Treat· April 2013

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Tissue microarray-based study of patients with lymph node-positive breast cancer shows tyrosine phosphorylation of signal transducer and activator of transcription 3 (tyrosine705-STAT3) is a marker of good prognosis.
Amir Sonnenblick, Anat Shriki, E Galun, Jonathan H Axelrod, Hagit Daum

Clin Transl Oncol· March 2012

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Diabetes blockade of sevoflurane postconditioning is not restored by insulin in the rat heart: phosphorylated signal transducer and activator of transcription 3- and phosphatidylinositol 3-kinase-mediated inhibition.
Benjamin Drenger, Israel A Ostrovsky, Michal Barak, Yael Nechemia-Arbely, Ehud Ziv, Jonathan H Axelrod

Anesthesiology· June 2011

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Early hepatocyte DNA synthetic response posthepatectomy is modulated by IL-6 trans-signaling and PI3K/AKT activation.
Yael Nechemia-Arbely, Anat Shriki, Ulrich Denz, Claudia Drucker, Jürgen Scheller, Jonathan H Axelrod

J Hepatol· May 2011

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