Publications by authors named "Jonathan B Cooper"

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The X-ray structure of juvenile hormone diol kinase from the silkworm Bombyx mori.
Jingxu Guo, Ronan M Keegan, Daniel J Rigden, Peter T Erskine, Steve P Wood, Jonathan B Cooper

Acta Crystallogr F Struct Biol Commun· December 2021

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The X-ray structure of L-threonine dehydrogenase from the common hospital pathogen Clostridium difficile.
Eyram Adjogatse, Josh Bennett, Jingxu Guo, Peter T Erskine, Steve P Wood, Jonathan B Cooper

Acta Crystallogr F Struct Biol Commun· August 2021

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-screening for discovery of human norovirus 3C-like protease inhibitors.
Jingxu Guo, Alice Douangamath, Weixiao Song, Alun R Coker, A W Edith Chan, Jonathan B Cooper

J Struct Biol X· July 2020

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Structural basis of pyrrole polymerization in human porphobilinogen deaminase.
Paula Pluta, Pietro Roversi, Ganeko Bernardo-Seisdedos, Adriana L Rojas, Jonathan B Cooper

Biochim Biophys Acta Gen Subj· September 2018

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Structure and function of L-threonine-3-dehydrogenase from the parasitic protozoan Trypanosoma brucei revealed by X-ray crystallography and geometric simulations.
Eyram Adjogatse, Peter Erskine, Stephen A Wells, John M Kelly, Jonathan D Wilden, Jonathan B Cooper

Acta Crystallogr D Struct Biol· September 2018

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Structure and function of the type III pullulan hydrolase from Thermococcus kodakarensis.
Jingxu Guo, Alun R Coker, Steve P Wood, Jonathan B Cooper, Ronan M Keegan

Acta Crystallogr D Struct Biol· April 2018

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Structural studies of domain movement in active-site mutants of porphobilinogen deaminase from Bacillus megaterium.
Jingxu Guo, Peter Erskine, Alun R Coker, Steve P Wood, Jonathan B Cooper

Acta Crystallogr F Struct Biol Commun· November 2017

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Structure and function of the thermostable L-asparaginase from Thermococcus kodakarensis.
Jingxu Guo, Alun R Coker, Steve P Wood, Jonathan B Cooper, Shahid Mahmood Chohan

Acta Crystallogr D Struct Biol· November 2017

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Structure of the family B DNA polymerase from the hyperthermophilic archaeon Pyrobaculum calidifontis.
Jingxu Guo, Wenling Zhang, Alun R Coker, Steve P Wood, Jonathan B Cooper

Acta Crystallogr D Struct Biol· May 2017

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Active-Site Protonation States in an Acyl-Enzyme Intermediate of a Class A β-Lactamase with a Monobactam Substrate.
Venu Gopal Vandavasi, Patricia S Langan, Kevin L Weiss, Jerry M Parks, Jonathan B Cooper

Antimicrob Agents Chemother· January 2017

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The structure of Toho1 β-lactamase in complex with penicillin reveals the role of Tyr105 in substrate recognition.
Patricia S Langan, Venu Gopal Vandavasi, Kevin L Weiss, Jonathan B Cooper, Stephan L Ginell

FEBS Open Bio· December 2016

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Impact of Deuteration on the Assembly Kinetics of Transthyretin Monitored by Native Mass Spectrometry and Implications for Amyloidoses.
Ai Woon Yee, Martine Moulin, Nina Breteau, Michael Haertlein, Edward P Mitchell, Jonathan B Cooper

Angew Chem Int Ed Engl· August 2016

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The 1.1 Å resolution structure of a periplasmic phosphate-binding protein from Stenotrophomonas maltophilia: a crystallization contaminant identified by molecular replacement using the entire Protein Data Bank.
Ronan Keegan, David G Waterman, David J Hopper, Leighton Coates, Graham Taylor, Jonathan B Cooper

Acta Crystallogr D Struct Biol· August 2016

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Binding of Gd(3+) to the neuronal signalling protein calexcitin identifies an exchangeable Ca(2+)-binding site.
Lucas Chataigner, Jingxu Guo, Peter T Erskine, Alun R Coker, Steve P Wood, Jonathan B Cooper

Acta Crystallogr F Struct Biol Commun· April 2016

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Exploring the Mechanism of β-Lactam Ring Protonation in the Class A β-lactamase Acylation Mechanism Using Neutron and X-ray Crystallography.
Venu Gopal Vandavasi, Kevin L Weiss, Jonathan B Cooper, Peter T Erskine, Stephen J Tomanicek

J Med Chem· January 2016

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Structure of a Kunitz-type potato cathepsin D inhibitor.
Jingxu Guo, Peter T Erskine, Alun R Coker, Steve P Wood, Jonathan B Cooper

J Struct Biol· December 2015

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Structure-based design and functional studies of novel noroviral 3C protease chimaeras offer insights into substrate specificity.
Morgan R Herod, Cynthia A Prince, Rachel J Skilton, Vernon K Ward, Jonathan B Cooper

Biochem J· December 2014

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Preliminary neutron crystallographic study of human transthyretin.
Melina Haupt, Matthew P Blakeley, Susana C M Teixeira, Sax A Mason, Edward P Mitchell, Jonathan B Cooper

Acta Crystallogr Sect F Struct Biol Cryst Commun· November 2011

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A structural study of norovirus 3C protease specificity: binding of a designed active site-directed peptide inhibitor.
Robert J Hussey, Leighton Coates, Raj S Gill, Peter T Erskine, Shu-Fen Coker, Jonathan B Cooper

Biochemistry· January 2011

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Mechanisms of resistance to EGFR inhibitors in head and neck cancer.
Jonathan B Cooper, Ezra Eddy Wyssam Cohen

Head Neck· August 2009

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Structure of human porphobilinogen deaminase at 2.8 A: the molecular basis of acute intermittent porphyria.
Raj Gill, Simon E Kolstoe, Fiyaz Mohammed, Abeer Al D-Bass, Julie E Mosely, Jonathan B Cooper

Biochem J· April 2009

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X-ray, neutron and NMR studies of the catalytic mechanism of aspartic proteinases.
Leighton Coates, Peter T Erskine, Sanjay Mall, Raj Gill, Steve P Wood, Jonathan B Cooper

Eur Biophys J· September 2006

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The 1.6A X-ray structure of the unusual c-type cytochrome, cytochrome cL, from the methylotrophic bacterium Methylobacterium extorquens.
Paul Williams, Leighton Coates, Fiyaz Mohammed, Raj Gill, Peter Erskine, Jonathan B Cooper

J Mol Biol· March 2006

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X-ray structure of a putative reaction intermediate of 5-aminolaevulinic acid dehydratase.
Peter T Erskine, Leighton Coates, Danica Butler, James H Youell, Amanda A Brindley, Jonathan B Cooper

Biochem J· August 2003

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Engineering of an intersubunit disulfide bridge in the iron-superoxide dismutase of Mycobacterium tuberculosis.
Karen A Bunting, Jonathan B Cooper, Ian J Tickle, Douglas B Young

Arch Biochem Biophys· January 2002

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