Publications by authors named "Jonathan Butcher"

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Unidirectional Shear Stress-Operated NOTCH/CXCR4 Molecular Switch Controls Semilunar Valve Maturation and Collagen Stratification.
Charles R Dai, Duc H Pham, G Janani, Belle Lin, Bin Zhou, Jonathan T Butcher

Arterioscler Thromb Vasc Biol· December 2025

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Pro-regenerative anisotropic nanofiber heart valve scaffold by inducing directional cell growth.
Baoding Chen, Nianfang Ma, Hui He, Lining Wang, Cuiping Guo, Jonathan T Butcher

J Colloid Interface Sci· December 2025

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Spatiotemporal Atlas of Heart Development Reveals Blood-Flow-Dependent Cellular, Structural, Metabolic, and Spatial Remodeling.
Jooyoung Park, Shuofei Sun, Rohit Agarwal, Andreas Stephanou, Mong Lung Steven Poon, Jonathan Butcher

bioRxiv· December 2025

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Cyclic Equiaxial Stretch Induces Osteogenic Differentiation and Augments 3D Lesion Height in 3D Cocultured Aortic Valve Cells.
Alexander D Cruz, Jennifer M Richards, Ablajan Mahmut, Alexa N Wnorowski, Jonathan T Butcher

ACS Biomater Sci Eng· November 2025

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Incremental Stretch Increases Strength and Toughness while Growing Engineered Trileaflet Heart Valves.
Benjamin J Albert, John T Toftegaard, Gaetano Scuderi, Brianna Hou, Kathleen M Clifford, Jonathan T Butcher

ACS Biomater Sci Eng· October 2025

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Longitudinal Live Imaging Derived 4D Hemodynamics and Dynamic Tissue Mechanics Across Outflow Tract Morphogenesis.
Gening Dong, Jaehyun Rhee, Shivani Kumar, Molly E Drumm, Henrik Lauridsen, Jonathan T Butcher

bioRxiv· August 2025

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The Role of Matrix Stiffness and Viscosity on Lipid Phenotype and Fat Lineage Potential.
Chelsea J Stephens, Reina Kobayashi, Daniel C Berry, Jonathan T Butcher

Tissue Eng Part A· July 2025

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Inflammation via JAK-STAT/HIF-1α Drives Metabolic Changes in Pentose Phosphate Pathway and Glycolysis That Support Aortic Valve Cell Calcification.
Tania Sánchez-Bayuela, Mirian Peral-Rodrigo, Iván Parra-Izquierdo, Javier López, Cristina Gómez, Jonathan T Butcher

Arterioscler Thromb Vasc Biol· July 2025

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Compound Impacts of Fluvial Flooding and Sea-Level Rise on Benzo[]pyrene Transport in the Lower Darby Creek Area Superfund Site, Pennsylvania, USA.
Sean A Woznicki, Joshua Barber, Jonathan B Butcher, Jonathan Essoka, Maureen Harris

ACS ES T Water· July 2025

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Valve endothelial monolayer fissuring via RhoA activity induces 3D calcific aortic valve lesion emergence as revealed by a longitudinal live-imaging platform.
Katherine Driscoll, Santosh Balakrishnan, G Janani, Hrishika Gogineni, Alessandra Good, Jonathan Butcher

bioRxiv· June 2025

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Computational Fluid Dynamic Optimization of Micropatterned Surfaces: Towards Biofunctionalization of Artificial Organs.
Wenxuan He, Aminat M Ibrahim, Abhishek Karmakar, Shivani Tuli, Jonathan T Butcher

Bioengineering (Basel)· October 2024

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Biomechanical Remodeling of Aortic Valve Interstitial Cells During Calcified Lesion Formation In Vitro.
Justine Yushiuan Shih, Terence Gee, Gaetano Scuderi, Jonathan Butcher

Ann Biomed Eng· May 2024

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Future prospects in the tissue engineering of heart valves: a focus on the role of stem cells.
Benjamin J Albert, Jonathan T Butcher

Expert Opin Biol Ther· June 2023

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Quantitative 4D imaging of biomechanical regulation of ventricular growth and maturation.
Jae Min Cho, Mong Lung Steve Poon, Enbo Zhu, Jing Wang, Jonathan T Butcher

Curr Opin Biomed Eng· June 2023

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Spatial analysis of future climate risk to stormwater infrastructure.
Jonathan B Butcher, Saumya Sarkar, Thomas E Johnson, Afshin Shabani

J Am Water Resour Assoc· May 2023

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Shear and hydrostatic stress regulate fetal heart valve remodeling through YAP-mediated mechanotransduction.
Mingkun Wang, Belle Yanyu Lin, Shuofei Sun, Charles Dai, Feifei Long, Jonathan T Butcher

Elife· April 2023

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Soft, strong, tough, and durable protein-based fiber hydrogels.
Mingkun Wang, Shuofei Sun, Gening Dong, Feifei Long, Jonathan T Butcher

Proc Natl Acad Sci U S A· February 2023

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Biological Response to Sintered Titanium in Left Ventricular Assist Devices: Pseudoneointima, Neointima, and Pannus.
Wenxuan He, Jonathan T Butcher, Grant W Rowlands, James F Antaki

ASAIO J· January 2023

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Geographic Analysis of the Vulnerability of U.S. Lakes to Cyanobacterial Blooms under Future Climate.
Jonathan B Butcher, Mark Fernandez, Thomas E Johnson, Afshin Shabani, Sylvia S Lee

Earth Interact· January 2023

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A SOX17-PDGFB signaling axis regulates aortic root development.
Pengfei Lu, Ping Wang, Bingruo Wu, Yidong Wang, Yang Liu, Jonathan T Butcher

Nat Commun· July 2022

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Tri-Layered and Gel-Like Nanofibrous Scaffolds with Anisotropic Features for Engineering Heart Valve Leaflets.
Shaohua Wu, Yiran Li, Caidan Zhang, Litao Tao, Mitchell Kuss, Jonathan Butcher

Adv Healthc Mater· May 2022

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Rac1 mediates cadherin-11 induced cellular pathogenic processes in aortic valve calcification.
Kiran A Vaidya, Matthew P Donnelly, Ablajan Mahmut, Jae Woong Jang, Terence W Gee, Jonathan T Butcher

Cardiovasc Pathol· March 2022

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A review of climate change effects on practices for mitigating water quality impacts.
Thomas Johnson, Jonathan Butcher, Stephanie Santell, Sara Schwartz, Susan Julius

J Water Clim Chang· March 2022

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OCT4-mediated inflammation induces cell reprogramming at the origin of cardiac valve development and calcification.
Emily J Farrar, Emilye Hiriart, Ablajan Mahmut, Bernd Jagla, David S Peal, Jonathan T Butcher

Sci Adv· November 2021

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A coupled hydrodynamic (HEC-RAS 2D) and water quality model (WASP) for simulating flood-induced soil, sediment, and contaminant transport.
Afshin Shabani, Sean A Woznicki, Megan Mehaffey, Jonathan Butcher, Tim A Wool

J Flood Risk Manag· July 2021

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