Publications by authors named "Jonathan C Zhao"

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EZH2 crosstalk with RNA methylation promotes prostate cancer progression through modulation of m6A autoregulation pathway.
Yang Yi, Joshua Fry, Chaehyun Yum, Rui Wang, Siqi Wu, Jonathan C Zhao

J Clin Invest· November 2025

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Targeting p300 and CBP abolishes HOXB13-loss-induced lipogenesis and tumor metastasis.
Xiaodong Lu, Liu Peng, Qi Chu, Samantha Ye, Mingyang Liu, Jonathan C Zhao

JCI Insight· November 2025

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Disruption of ARID1B Recruitment to the Nuclear Pore Complex as a New Anticancer Therapeutic Strategy.
Olena Odnokoz, Anupam Banerjee, Xin Cui, Lidan Zeng, Amad Uddin, Jonathan C Zhao

Adv Sci (Weinh)· September 2025

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NKX2-1 drives neuroendocrine transdifferentiation of prostate cancer via epigenetic and 3D chromatin remodeling.
Xiaodong Lu, Viriya Keo, Irina Cheng, Wanqing Xie, Galina Gritsina, Jonathan C Zhao

Nat Genet· August 2025

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Epigenetic remodeling and 3D chromatin reorganization governed by NKX2-1 drive neuroendocrine prostate cancer.
Xiaodong Lu, Viriya Keo, Irina Cheng, Wanqing Xie, Galina Gritsina, Jonathan C Zhao

bioRxiv· December 2024

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Chemokine receptor CXCR7 activates Aurora Kinase A and promotes neuroendocrine prostate cancer growth.
Galina Gritsina, Ka-Wing Fong, Xiaodong Lu, Zhuoyuan Lin, Wanqing Xie, Jonathan C Zhao

J Clin Invest· August 2023

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Palmitoyl acyltransferase ZDHHC7 inhibits androgen receptor and suppresses prostate cancer.
Zhuoyuan Lin, Shivani Agarwal, Song Tan, Hongshun Shi, Xiaodong Lu, Jonathan C Zhao

Oncogene· June 2023

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PALI1 promotes tumor growth through competitive recruitment of PRC2 to G9A-target chromatin for dual epigenetic silencing.
Ka-Wing Fong, Jonathan C Zhao, Xiaodong Lu, Jung Kim, Andrea Piunti

Mol Cell· December 2022

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FOXA1 inhibits hypoxia programs through transcriptional repression of HIF1A.
Xiaohai Wang, Lourdes Brea, Xiaodong Lu, Galina Gritsina, Su H Park, Jonathan C Zhao

Oncogene· September 2022

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HOXB13 suppresses de novo lipogenesis through HDAC3-mediated epigenetic reprogramming in prostate cancer.
Xiaodong Lu, Ka-Wing Fong, Galina Gritsina, Fang Wang, Sylvan C Baca, Jonathan C Zhao

Nat Genet· May 2022

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Posttranslational regulation of FOXA1 by Polycomb and BUB3/USP7 deubiquitin complex in prostate cancer.
Su H Park, Ka-Wing Fong, Jung Kim, Fang Wang, Xiaodong Lu, Jonathan C Zhao

Sci Adv· April 2021

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Correction: Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer.
Shangze Li, Ka-Wing Fong, Galina Gritsina, Ali Zhang, Jonathan C Zhao

Cancer Res· May 2020

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Altered chromatin recruitment by FOXA1 mutations promotes androgen independence and prostate cancer progression.
Bohan Xu, Bing Song, Xiaodong Lu, Jung Kim, Ming Hu, Jonathan C Zhao

Cell Res· September 2019

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Activation of MAPK Signaling by CXCR7 Leads to Enzalutamide Resistance in Prostate Cancer.
Shangze Li, Ka-Wing Fong, Galina Gritsina, Ali Zhang, Jonathan C Zhao

Cancer Res· May 2019

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Targeting FOXA1-mediated repression of TGF-β signaling suppresses castration-resistant prostate cancer progression.
Bing Song, Su-Hong Park, Jonathan C Zhao, Ka-Wing Fong, Shangze Li

J Clin Invest· February 2019

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Polycomb- and Methylation-Independent Roles of EZH2 as a Transcription Activator.
Jung Kim, Yongik Lee, Xiaodong Lu, Bing Song, Ka-Wing Fong, Jonathan C Zhao

Cell Rep· December 2018

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TRIM28 protects TRIM24 from SPOP-mediated degradation and promotes prostate cancer progression.
Ka-Wing Fong, Jonathan C Zhao, Bing Song, Bin Zheng, Jindan Yu

Nat Commun· November 2018

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PRDM4 mediates YAP-induced cell invasion by activating leukocyte-specific integrin β2 expression.
Huan Liu, Xiaoming Dai, Xiaolei Cao, Huan Yan, Xinyan Ji, Jonathan C Zhao, Bin Zhao

EMBO Rep· June 2018

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BMI1 regulates androgen receptor in prostate cancer independently of the polycomb repressive complex 1.
Sen Zhu, Dongyu Zhao, Lin Yan, Weihua Jiang, Jung-Sun Kim, Jonathan C Zhao

Nat Commun· February 2018

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Organoids model distinct Vitamin E effects at different stages of prostate cancer evolution.
Rose N Njoroge, Kenji Unno, Jonathan C Zhao, Anum F Naseem, Jonathan F Anker

Sci Rep· November 2017

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Many si/shRNAs can kill cancer cells by targeting multiple survival genes through an off-target mechanism.
William Putzbach, Quan Q Gao, Monal Patel, Stijn van Dongen, Ashley Haluck-Kangas, Jonathan C Zhao

Elife· October 2017

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Downregulation of GATA1 drives impaired hematopoiesis in primary myelofibrosis.
Laure Gilles, Ahmet Dirim Arslan, Christian Marinaccio, Qiang Jeremy Wen, Priyanka Arya, Jonathan C Zhao

J Clin Invest· April 2017

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CD95/Fas Increases Stemness in Cancer Cells by Inducing a STAT1-Dependent Type I Interferon Response.
Abdul S Qadir, Paolo Ceppi, Sonia Brockway, Calvin Law, Liang Mu, Jonathan C Zhao

Cell Rep· March 2017

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Polycomb-Mediated Disruption of an Androgen Receptor Feedback Loop Drives Castration-Resistant Prostate Cancer.
Ka-Wing Fong, Jonathan C Zhao, Jung Kim, Shangze Li, Yeqing A Yang

Cancer Res· January 2017

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FOXA1 potentiates lineage-specific enhancer activation through modulating TET1 expression and function.
Yeqing A Yang, Jonathan C Zhao, Ka-Wing Fong, Jung Kim, Shangze Li

Nucleic Acids Res· September 2016

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