Publications by authors named "Jonathan Chernoff"

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PAK2-driven cytoskeleton-endosome dynamics control macrophage hyperphagia and SIRPA engagement.
Julie Drieu La Rochelle, Joseph P Cassidy, Jonathan Chernoff, Ulla G Knaus

Proc Natl Acad Sci U S A· November 2025

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PAK1 regulates oligodendroglial proliferation and repopulation in homeostatic and demyelinating brain.
Yan Wang, Bokyung Kim, Xiangyi Shi, Huimin Chen, Joohyun Park, Jonathan Chernoff

Cell Mol Life Sci· June 2025

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Treatment discontinuation associated with perioperative toxicity of FLOT versus XELOX chemotherapy in patients with resectable gastric cancer: prospective randomized trial (PECORINO).
Oleksii Dobrzhanskyi, Vjacheslav Kopetskyi, Eric A Ross, Jonathan Chernoff, Yevhenii Shudrak

J Gastrointest Oncol· June 2025

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Identifying and Targeting Key Driver Genes for Collagen Production within the 11q13/14 Breast Cancer Amplicon.
Daniela Araiza-Olivera, Tatiana Y Prudnikova, Cristina Uribe-Alvarez, Kathy Q Cai, Janusz Franco-Barraza, Jonathan Chernoff

Mol Cancer Res· May 2025

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KRAS G12V mutation-selective requirement for ACSS2 in colorectal adenoma formation.
Konstantin Budagyan, Alexa C Cannon, Adam Chatoff, Dorothy Benton, Alison M Kurimchak, Jonathan Chernoff

Cell Rep· April 2025

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The role of RAC1 in resistance to targeted therapies in cancer.
Cristina Uribe-Alvarez, Jonathan Chernoff

Small GTPases· December 2024

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Synergistic effect of PAK and Hippo pathway inhibitor combination in NF2-deficient Schwannoma.
Dorothy Benton, Hoi Yee Chow, Sofiia Karchugina, Jonathan Chernoff

PLoS One· July 2024

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PAK2 is necessary for myelination in the peripheral nervous system.
Bo Hu, Daniel Moiseev, Isabella Schena, Bulat Faezov, Roland Dunbrack, Jonathan Chernoff

Brain· May 2024

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A Facile Method to Append a Bio-ID Tag to Endogenous Mutant Kras Alleles.
Konstantin Budagyan, Alexa C Cannon, Jonathan Chernoff

Methods Mol Biol· April 2024

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Control of OPC proliferation and repopulation by the intellectual disability gene PAK1 under homeostatic and demyelinating conditions.
Yan Wang, Bokyung Kim, Shuaishuai Gong, Joohyun Park, Meina Zhu, Jonathan Chernoff

bioRxiv· April 2024

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Unique vulnerability of RAC1-mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
Alexa C Cannon, Konstantin Budagyan, Cristina Uribe-Alvarez, Alison M Kurimchak, Daniela Araiza-Olivera, Jonathan Chernoff

Oncogene· March 2024

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Identifying and targeting key driver genes for collagen production within the 11q13/14 breast cancer amplicon.
Daniela Araiza-Olivera, Tatiana Y Prudnikova, Cristina Uribe-Alvarez, Kathy Q Cai, Janusz Franco-Barraza, Jonathan Chernoff

bioRxiv· March 2024

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KRAS mutation-selective requirement for ACSS2 in colorectal adenoma formation.
Konstantin Budyagan, Alexa C Cannon, Adam Chatoff, Nathaniel W Snyder, Alison M Kurimchak, Jonathan Chernoff

Res Sq· February 2024

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A PTP1B-Cdk3 Signaling Axis Promotes Cell Cycle Progression of Human Glioblastoma Cells through an Rb-E2F Dependent Pathway.
Olga Villamar-Cruz, Marco Antonio Loza-Mejía, Alonso Vivar-Sierra, Héctor Iván Saldivar-Cerón, Genaro Patiño-López, Jonathan Chernoff

Mol Cell Biol· December 2023

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RHOA drivers take alternate routes in gastric cancer.
Dorothy Benton, Jonathan Chernoff

Sci Signal· December 2023

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The TRIM69-MST2 signaling axis regulates centrosome dynamics and chromosome segregation.
Yilin Wang, Patrik Risteski, Yang Yang, Huan Chen, Gaith Droby, Jonathan Chernoff

Nucleic Acids Res· October 2023

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Expression of Concern: α6β4 integrin activates Rac-dependent p21-activated kinase 1 to drive NF-κB-dependent resistance to apoptosis in 3D mammary acini.
Julie C Friedland, Johnathon N Lakins, Marcelo G Kazanietz, Jonathan Chernoff, David Boettiger

J Cell Sci· October 2023

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TRIMming away colon cancer: TRIM21-mediated ubiquitination as an activator of the Hippo tumor suppressor pathway.
Dorothy Benton, Jonathan Chernoff

Cell Chem Biol· July 2023

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Unique vulnerability of -mutant melanoma to combined inhibition of CDK9 and immune checkpoints.
Alexa C Cannon, Konstantin Budagyan, Cristina Uribe-Alvarez, Alison M Kurimchak, Daniela Araiza-Olivera, Jonathan Chernoff

bioRxiv· June 2023

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Targeting P21-Activated Kinase-1 for Metastatic Prostate Cancer.
Payaningal R Somanath, Jonathan Chernoff, Brian S Cummings, Sandip M Prasad, Harvey D Homan

Cancers (Basel)· April 2023

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Development and Utility of a PAK1-Selective Degrader.
Hoi-Yee Chow, Sofiia Karchugina, Brian J Groendyke, Sean Toenjes, John Hatcher, Jonathan Chernoff

J Med Chem· December 2022

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Pak2-mediated phosphorylation promotes RORγt ubiquitination and inhibits colonic inflammation.
Mahesh Kathania, Ritesh Kumar, Elviche Taskem Lenou, Venkatesha Basrur, Arianne L Theiss, Jonathan Chernoff

Cell Rep· September 2022

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Paracrine signal emanating from stressed cardiomyocytes aggravates inflammatory microenvironment in diabetic cardiomyopathy.
Namrita Kaur, Andrea Ruiz-Velasco, Rida Raja, Gareth Howell, Jessica M Miller, Jonathan Chernoff

iScience· March 2022

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Pak2 Regulation of Nrf2 Serves as a Novel Signaling Nexus Linking ER Stress Response and Oxidative Stress in the Heart.
Pablo Binder, Binh Nguyen, Lucy Collins, Min Zi, Wei Liu, Jonathan Chernoff

Front Cardiovasc Med· March 2022

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p21-Activated Kinase 1 Promotes Breast Tumorigenesis Phosphorylation and Activation of the Calcium/Calmodulin-Dependent Protein Kinase II.
Héctor I Saldivar-Cerón, Olga Villamar-Cruz, Claire M Wells, Ibrahim Oguz, Federica Spaggiari, Jonathan Chernoff

Front Cell Dev Biol· January 2022

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