Publications by authors named "Jonathan D Licht"

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Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR T cells.
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar, Amrik S Kang, Nikhil Chilakapati, Jonathan D Licht

Blood· August 2025

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Association of Glucagon-Like Peptide-1 Receptor Agonists With Cancer Risk in Older Adults With Type 2 Diabetes.
Ying Lu, Hao Dai, Huilin Tang, William T Donahoo, Thomas J George, Jonathan D Licht

Obesity (Silver Spring)· August 2025

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A multi-step immune-competent genetic mouse model reveals phenotypic plasticity in uveal melanoma.
Xiaonan Xu, Xiaoxian Liu, James J Dollar, Xiao Liu, Neel Jasani, Jonathan D Licht

bioRxiv· June 2025

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GDF15 reprograms the microenvironment to drive the development of uveal melanoma liver metastases.
Sathya Neelature Sriramareddy, Navya Siddarajappa, Jun Sung Park, Thanh Nguyen, Jeffim N Kuznetsoff, Jonathan D Licht

bioRxiv· May 2025

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The C-terminal PHDVC5HCH tandem domain of NSD2 is a combinatorial reader of unmodified H3K4 and tri-methylated H3K27 that regulates transcription of cell adhesion genes in multiple myeloma.
Andrea Berardi, Charlotte Leonie Kaestner, Michela Ghitti, Giacomo Quilici, Paolo Cocomazzi, Jonathan D Licht

Nucleic Acids Res· January 2025

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Recruitment of FBXO22 for targeted degradation of NSD2.
David Y Nie, John R Tabor, Jianping Li, Maria Kutera, Jonathan St-Germain, Jonathan D Licht

Nat Chem Biol· December 2024

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Aberrant expression of histone H2B variants reshape chromatin and alter oncogenic gene expression programs.
Wesley N Saintilnord, Youssef A Hegazy, Kristin Chesnutt, Meredith Eckstein, Richard N Cassidy, Jonathan D Licht

bioRxiv· November 2024

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KDM6A regulates immune response genes in multiple myeloma.
Daphné Dupéré-Richer, Alberto Riva, Benjamin G Barwick, Sayantan Maji, Heidi Casellas Román, Jonathan D Licht

Blood· October 2024

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Genetic variation drives cancer cell adaptation to ECM stiffness.
Ting-Ching Wang, Suchitaa Sawhney, Daylin Morgan, Richard L Bennett, Richa Rashmi, Jonathan D Licht

Proc Natl Acad Sci U S A· September 2024

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NSD2 drives t(4;14) myeloma cell dependence on adenylate kinase 2 by diverting one-carbon metabolism to the epigenome.
Amin Sobh, Elena Encinas, Alisha Patel, Greeshma Surapaneni, Emilie Bonilla, Jonathan D Licht

Blood· July 2024

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KDM6A Regulates Immune Response Genes in Multiple Myeloma.
Daphne Dupéré-Richer, Alberto Riva, Sayantan Maji, Benjamin G Barwick, Heidi Casellas Román, Jonathan D Licht

bioRxiv· February 2024

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Targeting high-risk multiple myeloma genotypes with optimized anti-CD70 CAR-T cells.
Corynn Kasap, Adila Izgutdina, Bonell Patiño-Escobar, Amrik Kang, Nikhil Chilakapati, Jonathan D Licht

bioRxiv· February 2024

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Recruitment of FBXO22 for Targeted Degradation of NSD2.
David Y Nie, John R Tabor, Jianping Li, Maria Kutera, Jonathan St-Germain, Jonathan D Licht

bioRxiv· November 2023

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HDAC8-mediated inhibition of EP300 drives a transcriptional state that increases melanoma brain metastasis.
Michael F Emmons, Richard L Bennett, Alberto Riva, Kanchan Gupta, Larissa Anastasio Da Costa Carvalho, Jonathan D Licht

Nat Commun· November 2023

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HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.
Viacheslav M Morozov, Alberto Riva, Sadia Sarwar, Wan-Ju Kim, Jianping Li, Jonathan D Licht

Nucleic Acids Res· October 2023

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Histone mutations in cancer.
Kimberly N Espinoza Pereira, Jixiu Shan, Jonathan D Licht, Richard L Bennett

Biochem Soc Trans· October 2023

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SMYD3 represses tumor-intrinsic interferon response in HPV-negative squamous cell carcinoma of the head and neck.
Nupur Nigam, Benjamin Bernard, Samantha Sevilla, Sohyoung Kim, Mohd Saleem Dar, Jonathan D Licht

Cell Rep· July 2023

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Cancer incidence after asthma diagnosis: Evidence from a large clinical research network in the United States.
Yi Guo, Jiang Bian, Zhaoyi Chen, Jennifer N Fishe, Dongyu Zhang, Jonathan D Licht

Cancer Med· May 2023

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HIRA-mediated loading of histone variant H3.3 controls androgen-induced transcription by regulation of AR/BRD4 complex assembly at enhancers.
Viacheslav M Morozov, Alberto Riva, Sadia Sarwar, WanJu Kim, Jianping Li, Jonathan D Licht

bioRxiv· May 2023

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Genome-scale functional genomics identify genes preferentially essential for multiple myeloma cells compared to other neoplasias.
Ricardo de Matos Simoes, Ryosuke Shirasaki, Sondra L Downey-Kopyscinski, Geoffrey M Matthews, Benjamin G Barwick, Jonathan D Licht

Nat Cancer· May 2023

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Discovery of a Potent and Selective Targeted NSD2 Degrader for the Reduction of H3K36me2.
Ronan P Hanley, David Y Nie, John R Tabor, Fengling Li, Amin Sobh, Jonathan D Licht

J Am Chem Soc· April 2023

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First-in-class multifunctional TYMS nonclassical antifolate inhibitor with potent in vivo activity that prolongs survival.
Maria V Guijarro, Patrick C Kellish, Peter E Dib, Nicholas G Paciaroni, Akbar Nawab, Jonathan D Licht

JCI Insight· April 2023

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Low muscle mass is associated with a higher risk of all-cause and cardiovascular disease-specific mortality in cancer survivors.
Dongyu Zhang, Kori A Spiropoulos, Akemi Wijayabahu, Demetra D Christou, Shama D Karanth, Jonathan D Licht

Nutrition· March 2023

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Piperlongumine conjugates induce targeted protein degradation.
Jing Pei, Yufeng Xiao, Xingui Liu, Wanyi Hu, Amin Sobh, Jonathan D Licht

Cell Chem Biol· February 2023

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BAP1 Loss Promotes Suppressive Tumor Immune Microenvironment via Upregulation of PROS1 in Class 2 Uveal Melanomas.
Christopher J Kaler, James J Dollar, Anthony M Cruz, Jeffim N Kuznetsoff, Margaret I Sanchez, Jonathan D Licht

Cancers (Basel)· July 2022

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