Publications by authors named "Jonathan D Silk"

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MR1-ligand cross-linking identifies vitamin B6 metabolites as TCR-reactive antigens.
Thierry Schmidlin, Enas Behiry, Hannah Thomas, Garry Dolton, Fabio Marino, Jonathan D Silk

Cell Rep Methods· August 2025

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Conserved allomorphs of MR1 drive the specificity of MR1-restricted TCRs.
Terri V Cornforth, Nathifa Moyo, Suzanne Cole, Emily P S Lam, Tatiana Lobry, Jonathan D Silk

Front Oncol· October 2024

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Enhancing Efficacy of TCR-engineered CD4 + T Cells Via Coexpression of CD8α.
Victoria E Anderson, Sara S Brilha, Anika M Weber, Annette Pachnio, Guy E Wiedermann, Jonathan D Silk

J Immunother· May 2023

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Engineering Cancer Antigen-Specific T Cells to Overcome the Immunosuppressive Effects of TGF-β.
Jonathan D Silk, Rachel J M Abbott, Katherine J Adams, Alan D Bennett, Sara Brett

J Immunol· January 2022

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Generation and characterization of HLA-A2 transgenic mice expressing the human TCR 1G4 specific for the HLA-A2 restricted NY-ESO-1 tumor-specific peptide.
Eugene Shenderov, Matheswaran Kandasamy, Uzi Gileadi, Jili Chen, Dawn Shepherd, Jonathan D Silk

J Immunother Cancer· June 2021

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Nutritional Stress Induced by Tryptophan-Degrading Enzymes Results in ATF4-Dependent Reprogramming of the Amino Acid Transporter Profile in Tumor Cells.
Elina Timosenko, Hemza Ghadbane, Jonathan D Silk, Dawn Shepherd, Uzi Gileadi

Cancer Res· November 2016

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Biology of CD1- and MR1-restricted T cells.
Mariolina Salio, Jonathan D Silk, E Yvonne Jones, Vincenzo Cerundolo

Annu Rev Immunol· November 2014

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Pseudotyped influenza A virus as a vaccine for the induction of heterotypic immunity.
Timothy J Powell, Jonathan D Silk, Jane Sharps, Ervin Fodor, Alain R M Townsend

J Virol· December 2012

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IDO induces expression of a novel tryptophan transporter in mouse and human tumor cells.
Jonathan D Silk, Samira Lakhal, Robert Laynes, Laura Vallius, Ioannis Karydis

J Immunol· August 2011

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T cell receptor CDR3 loops influence alphabeta pairing.
Istvan Bartok, Stephen J Holland, Helmut W Kessels, Jonathan D Silk, Mooza Alkhinji

Mol Immunol· April 2010

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Recent advances in processing and presentation of CD1 bound lipid antigens.
Mariolina Salio, Jonathan D Silk, Vincenzo Cerundolo

Curr Opin Immunol· February 2010

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Aberrant selection and function of invariant NKT cells in the absence of AP-1 transcription factor Fra-2.
Victoria J Lawson, Diane Maurice, Jonathan D Silk, Vincenzo Cerundolo, Kathleen Weston

J Immunol· August 2009

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Nonglycosidic agonists of invariant NKT cells for use as vaccine adjuvants.
B Gopal Reddy, Jonathan D Silk, Mariolina Salio, Rengarajan Balamurugan, Dawn Shepherd

ChemMedChem· February 2009

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Harnessing invariant NKT cells in vaccination strategies.
Vincenzo Cerundolo, Jonathan D Silk, S Hajar Masri, Mariolina Salio

Nat Rev Immunol· January 2009

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Structural and functional aspects of lipid binding by CD1 molecules.
Jonathan D Silk, Mariolina Salio, James Brown, E Yvonne Jones, Vincenzo Cerundolo

Annu Rev Cell Dev Biol· December 2008

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Cutting edge: nonglycosidic CD1d lipid ligands activate human and murine invariant NKT cells.
Jonathan D Silk, Mariolina Salio, B Gopal Reddy, Dawn Shepherd, Uzi Gileadi

J Immunol· May 2008

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Dendritic cell function can be modulated through cooperative actions of TLR ligands and invariant NKT cells.
Ian F Hermans, Jonathan D Silk, Uzi Gileadi, S Hajar Masri, Dawn Shepherd

J Immunol· March 2007

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Impaired selection of invariant natural killer T cells in diverse mouse models of glycosphingolipid lysosomal storage diseases.
Stephan D Gadola, Jonathan D Silk, Aruna Jeans, Petr A Illarionov, Mariolina Salio

J Exp Med· October 2006

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Regulation of hematopoiesis in vitro and in vivo by invariant NKT cells.
Ioannis Kotsianidis, Jonathan D Silk, Emmanouil Spanoudakis, Scott Patterson, Antonio Almeida

Blood· April 2006

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Mixed-haplotype MHC class II molecules select functional CD4+ T cells.
Jonathan D Silk, Diana Schoendorf, Istvan Bartok, Jian-Guo Chai, David Gray

Mol Immunol· June 2005

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Utilizing the adjuvant properties of CD1d-dependent NK T cells in T cell-mediated immunotherapy.
Jonathan D Silk, Ian F Hermans, Uzi Gileadi, Tsung Wen Chong, Dawn Shepherd

J Clin Invest· December 2004

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The VITAL assay: a versatile fluorometric technique for assessing CTL- and NKT-mediated cytotoxicity against multiple targets in vitro and in vivo.
Ian F Hermans, Jonathan D Silk, Jianping Yang, Michael J Palmowski, Uzi Gileadi

J Immunol Methods· February 2004

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High avidity antigen-specific CTL identified by CD8-independent tetramer staining.
Ed Man-Lik Choi, Ji-Li Chen, Linda Wooldridge, Mariolina Salio, Anna Lissina, Jonathan D Silk

J Immunol· November 2003

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NKT cells enhance CD4+ and CD8+ T cell responses to soluble antigen in vivo through direct interaction with dendritic cells.
Ian F Hermans, Jonathan D Silk, Uzi Gileadi, Mariolina Salio, Bini Mathew

J Immunol· November 2003

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