Publications by authors named "Jonathan Derry"

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In Situ Proinflammatory Effects of Dazostinag Alone or with Chemotherapy on the Tumor Microenvironment of Patients with Head and Neck Squamous Cell Carcinoma.
Richard C Gregory, Neil Lineberry, Alex Parent, Karthik Rajasekaran, Thomas J Ow, Jonathan M J Derry

Cancer Res Commun· July 2025

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Early, precise, and safe clinical evaluation of the pharmacodynamic effects of novel agents in the intact human tumor microenvironment.
Kenneth R Gundle, Karthik Rajasekaran, Jeffrey Houlton, Gary B Deutsch, Thomas J Ow, Jonathan M J Derry

Front Pharmacol· April 2024

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Differential expression of transcripts as a novel prognostic biomarker in histologically diverse mesotheliomas.
Nancy Alnassar, Jonathan M J Derry, Giuseppe Luigi Banna, Dariusz C Gorecki

Transl Lung Cancer Res· April 2024

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Trackable Intratumor Microdosing and Spatial Profiling Provide Early Insights into Activity of Investigational Agents in the Intact Tumor Microenvironment.
Jonathan M J Derry, Connor Burns, Jason P Frazier, Emily Beirne, Marc Grenley

Clin Cancer Res· September 2023

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Altered gene expression in slc4a11 mouse cornea highlights SLC4A11 roles.
Bernardo V Alvarez, Marilyse Piché, Carolin Aizouki, Fariha Rahman, Jonathan M J Derry

Sci Rep· October 2021

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Pillars Article: Isolation of a Novel Gene Mutated in Wiskott-Aldrich Syndrome. . 1994. 78: 635-644.
Jonathan M J Derry, Hans D Ochs, Uta Francke

J Immunol· June 2018

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Gene expression elucidates functional impact of polygenic risk for schizophrenia.
Menachem Fromer, Panos Roussos, Solveig K Sieberts, Jessica S Johnson, David H Kavanagh, Jonathan M J Derry

Nat Neurosci· November 2016

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Modeling RAS phenotype in colorectal cancer uncovers novel molecular traits of RAS dependency and improves prediction of response to targeted agents in patients.
Justin Guinney, Charles Ferté, Jonathan Dry, Robert McEwen, Gilles Manceau, Jonathan Derry

Clin Cancer Res· January 2014

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Dominant effects of the Huntington's disease HTT CAG repeat length are captured in gene-expression data sets by a continuous analysis mathematical modeling strategy.
Jong-Min Lee, Ekaterina I Galkina, Rachel M Levantovsky, Elisa Fossale, Mary Anne Anderson, Jonathan Derry

Hum Mol Genet· August 2013

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A systems biology framework identifies molecular underpinnings of coronary heart disease.
Tianxiao Huan, Bin Zhang, Zhi Wang, Roby Joehanes, Jun Zhu, Jonathan Derry

Arterioscler Thromb Vasc Biol· June 2013

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Lung eQTLs to help reveal the molecular underpinnings of asthma.
Ke Hao, Yohan Bossé, David C Nickle, Peter D Paré, Dirkje S Postma, Jonathan M Derry

PLoS Genet· May 2013

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Crowdsourcing genetic prediction of clinical utility in the Rheumatoid Arthritis Responder Challenge.
Robert M Plenge, Jeffrey D Greenberg, Lara M Mangravite, Jonathan M J Derry, Eli A Stahl

Nat Genet· May 2013

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Resolving candidate genes of mouse skeletal muscle QTL via RNA-Seq and expression network analyses.
Arimantas Lionikas, Caroline Meharg, Jonathan Mj Derry, Aivaras Ratkevicius, Andrew M Carroll

BMC Genomics· November 2012

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Secreted frizzled-related protein 4 reduces insulin secretion and is overexpressed in type 2 diabetes.
Taman Mahdi, Sonja Hänzelmann, Albert Salehi, Sarheed J Muhammed, Thomas M Reinbothe, Jonathan Derry

Cell Metab· November 2012

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Developing predictive molecular maps of human disease through community-based modeling.
Jonathan M J Derry, Lara M Mangravite, Christine Suver, Matthew D Furia, David Henderson

Nat Genet· January 2012

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Predictive genes in adjacent normal tissue are preferentially altered by sCNV during tumorigenesis in liver cancer and may rate limiting.
John R Lamb, Chunsheng Zhang, Tao Xie, Kai Wang, Bin Zhang, Jonathan Derry

PLoS One· December 2011

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Identification of genes and networks driving cardiovascular and metabolic phenotypes in a mouse F2 intercross.
Jonathan M J Derry, Hua Zhong, Cliona Molony, Doug MacNeil, Debraj Guhathakurta

PLoS One· December 2010

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Integrative genomics and drug development.
Pek Y Lum, Jonathan M J Derry, Eric E Schadt

Pharmacogenomics· February 2009

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Differentially regulated functional gene clusters identified during ischemia and reperfusion in isolated cardiac myocytes using coverslip hypoxia.
Kelly R Pitts, Jonathan M J Derry, Keith Kerkof, William A Lawrence, Christopher F Toombs

J Pharmacol Toxicol Methods· October 2008

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Mapping the genetic architecture of gene expression in human liver.
Eric E Schadt, Cliona Molony, Eugene Chudin, Ke Hao, Xia Yang, Jonathan Derry

PLoS Biol· May 2008

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Tumor suppressor CYLD regulates acute lung injury in lethal Streptococcus pneumoniae infections.
Jae Hyang Lim, Brigid Stirling, Jonathan Derry, Tomoaki Koga, Hirofumi Jono

Immunity· August 2007

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Impaired regulation of NF-kappaB and increased susceptibility to colitis-associated tumorigenesis in CYLD-deficient mice.
Jun Zhang, Brigid Stirling, Stephane T Temmerman, Chi A Ma, Ivan J Fuss, Jonathan M J Derry

J Clin Invest· November 2006

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Impaired dendritic-cell function in ectodermal dysplasia with immune deficiency is linked to defective NEMO ubiquitination.
Stephane T Temmerman, Chi A Ma, Louis Borges, Marek Kubin, Shuying Liu, Jonathan M J Derry

Blood· October 2006

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Cutting edge: interleukin 17 signals through a heteromeric receptor complex.
Dean Toy, David Kugler, Martin Wolfson, Tim Vanden Bos, Jesse Gurgel, Jonathan Derry

J Immunol· July 2006

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