Publications by authors named "Jonathan H Fox"

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Cellular Localization of Kynurenine 3-Monooxygenase in the Brain: Challenging the Dogma.
Korrapati V Sathyasaikumar, Verónica Pérez de la Cruz, Benjamín Pineda, Gustavo Ignacio Vázquez Cervantes, Daniela Ramírez Ortega, Jonathan H Fox

Antioxidants (Basel)· February 2022

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Iron activates microglia and directly stimulates indoleamine-2,3-dioxygenase activity in the N171-82Q mouse model of Huntington's disease.
David W Donley, Marley Realing, Jason P Gigley, Jonathan H Fox

PLoS One· November 2021

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Novel proteomic changes in brain mitochondria provide insights into mitochondrial dysfunction in mouse models of Huntington's disease.
Sonal Agrawal, Jonathan H Fox

Mitochondrion· July 2019

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Brain mitochondrial iron accumulates in Huntington's disease, mediates mitochondrial dysfunction, and can be removed pharmacologically.
Sonal Agrawal, Julia Fox, Baskaran Thyagarajan, Jonathan H Fox

Free Radic Biol Med· May 2018

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Amyloid Precursor Protein Haploinsufficiency Preferentially Mediates Brain Iron Accumulation in Mice Transgenic for The Huntington's Disease Mutation.
Kiersten Berggren, Sonal Agrawal, Julia A Fox, Justin Hildenbrand, Ryan Nelson, Jonathan H Fox

J Huntingtons Dis· March 2018

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Acute hepatic steatosis: a helpful diagnostic feature in metallic phosphide-poisoned horses.
Jonathan H Fox, Brian F Porter, Leslie Easterwood, Justin R V Hildenbrand, Pierre Hélie

J Vet Diagn Invest· March 2018

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Huntingtons Disease Mice Infected with Toxoplasma gondii Demonstrate Early Kynurenine Pathway Activation, Altered CD8+ T-Cell Responses, and Premature Mortality.
David W Donley, Andrew R Olson, Merl F Raisbeck, Jonathan H Fox, Jason P Gigley

PLoS One· August 2017

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Impact of high iron intake on cognition and neurodegeneration in humans and in animal models: a systematic review.
Sonal Agrawal, Kiersten L Berggren, Eileen Marks, Jonathan H Fox

Nutr Rev· June 2017

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Neonatal Iron Supplementation Induces Striatal Atrophy in Female YAC128 Huntington's Disease Mice.
Kiersten L Berggren, Zhen Lu, Julia A Fox, Megan Dudenhoeffer, Sonal Agrawal, Jonathan H Fox

J Huntingtons Dis· December 2016

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Neonatal iron supplementation potentiates oxidative stress, energetic dysfunction and neurodegeneration in the R6/2 mouse model of Huntington's disease.
Kiersten L Berggren, Jianfang Chen, Julia Fox, Jonathan Miller, Lindsay Dodds, Jonathan H Fox

Redox Biol· June 2016

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Altered selenium status in Huntington's disease: neuroprotection by selenite in the N171-82Q mouse model.
Zhen Lu, Eileen Marks, Jianfang Chen, Jenna Moline, Lorraine Barrows, Jonathan H Fox

Neurobiol Dis· November 2014

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Iron accumulates in Huntington's disease neurons: protection by deferoxamine.
Jianfang Chen, Eileen Marks, Barry Lai, Zhaojie Zhang, James A Duce, Jonathan H Fox

PLoS One· August 2014

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Cysteine oxidation within N-terminal mutant huntingtin promotes oligomerization and delays clearance of soluble protein.
Jonathan H Fox, Teal Connor, Megan Stiles, Jibrin Kama, Zhen Lu

J Biol Chem· May 2011

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The mTOR kinase inhibitor Everolimus decreases S6 kinase phosphorylation but fails to reduce mutant huntingtin levels in brain and is not neuroprotective in the R6/2 mouse model of Huntington's disease.
Jonathan H Fox, Teal Connor, Vanita Chopra, Kate Dorsey, Jibrin A Kama

Mol Neurodegener· June 2010

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A small-molecule therapeutic lead for Huntington's disease: preclinical pharmacology and efficacy of C2-8 in the R6/2 transgenic mouse.
Vanita Chopra, Jonathan H Fox, Greg Lieberman, Kathryn Dorsey, Wayne Matson

Proc Natl Acad Sci U S A· October 2007

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Mechanisms of copper ion mediated Huntington's disease progression.
Jonathan H Fox, Jibrin A Kama, Gregory Lieberman, Raman Chopra, Kate Dorsey

PLoS One· March 2007

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Transcriptional dysregulation in striatal projection- and interneurons in a mouse model of Huntington's disease: neuronal selectivity and potential neuroprotective role of HAP1.
Birgit Zucker, Ruth Luthi-Carter, Jibrin A Kama, Anthone W Dunah, Edward A Stern, Jonathan H Fox

Hum Mol Genet· January 2005

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Cystamine increases L-cysteine levels in Huntington's disease transgenic mouse brain and in a PC12 model of polyglutamine aggregation.
Jonathan H Fox, David S Barber, Bhupinder Singh, Birgit Zucker, Mary K Swindell

J Neurochem· October 2004

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Altered expression of transcripts for alpha-tubulin and an unidentified gene in the spinal cord of phenyl saligenin phosphate treated hens (Gallus gallus).
Jonathan H Fox, Bernard S Jortner, David Barber, Marion F Ehrich

J Biochem Mol Toxicol· June 2004

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