Publications by authors named "Jonathan Hurov"

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Selective Vulnerability to Pyrimidine Starvation in Hematologic Malignancies Revealed by AG-636, a Novel Clinical-Stage Inhibitor of Dihydroorotate Dehydrogenase.
Gabrielle McDonald, Victor Chubukov, John Coco, Kevin Truskowski, Rohini Narayanaswamy, Jonathan Hurov

Mol Cancer Ther· December 2020

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Roadmap for the Emerging Field of Cancer Neuroscience.
Michelle Monje, Jeremy C Borniger, Nisha J D'Silva, Benjamin Deneen, Peter B Dirks, Jonathan B Hurov

Cell· April 2020

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Mesenchymal phenotype predisposes lung cancer cells to impaired proliferation and redox stress in response to glutaminase inhibition.
Danielle B Ulanet, Kiley Couto, Abhishek Jha, Sung Choe, Amanda Wang, Jonathan B Hurov

PLoS One· March 2016

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Targeting metabolic changes in cancer: novel therapeutic approaches.
Ekaterina Bobrovnikova-Marjon, Jonathan B Hurov

Annu Rev Med· September 2014

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Action at a distance: allostery and the development of drugs to target cancer cell metabolism.
Byron DeLaBarre, Jonathan Hurov, Giovanni Cianchetta, Stuart Murray, Lenny Dang

Chem Biol· September 2014

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Depletion of a putatively druggable class of phosphatidylinositol kinases inhibits growth of p53-null tumors.
Brooke M Emerling, Jonathan B Hurov, George Poulogiannis, Kazumi S Tsukazawa, Rayman Choo-Wing

Cell· November 2013

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Full-length human glutaminase in complex with an allosteric inhibitor.
Byron DeLaBarre, Stefan Gross, Cheng Fang, Yi Gao, Abhishek Jha, Jonathan B Hurov

Biochemistry· December 2011

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Loss of Par-1a/MARK3/C-TAK1 kinase leads to reduced adiposity, resistance to hepatic steatosis, and defective gluconeogenesis.
Jochen K Lennerz, Jonathan B Hurov, Lynn S White, Katherine T Lewandowski, Julie L Prior

Mol Cell Biol· November 2010

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GPAT3 and GPAT4 are regulated by insulin-stimulated phosphorylation and play distinct roles in adipogenesis.
Dandan Shan, Jian-liang Li, Leeying Wu, Dongmei Li, Jonathan Hurov

J Lipid Res· July 2010

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The Par-1/MARK family of protein kinases: from polarity to metabolism.
Jonathan Hurov, Helen Piwnica-Worms

Cell Cycle· August 2007

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Loss of the Par-1b/MARK2 polarity kinase leads to increased metabolic rate, decreased adiposity, and insulin hypersensitivity in vivo.
Jonathan B Hurov, Mei Huang, Lynn S White, Jochen Lennerz, Cheol Soo Choi

Proc Natl Acad Sci U S A· March 2007

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Characterization of the megakaryocyte demarcation membrane system and its role in thrombopoiesis.
Harald Schulze, Manav Korpal, Jonathan Hurov, Sang-We Kim, Jinghang Zhang

Blood· May 2006

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Atypical PKC phosphorylates PAR-1 kinases to regulate localization and activity.
Jonathan B Hurov, Janis L Watkins, Helen Piwnica-Worms

Curr Biol· April 2004

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