Publications by authors named "Jonathan Kehler"

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Author Correction: Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension.
Shan-Shan Zhang, Lance Larrabee, Andrew H Chang, Sapna Desai, Lisa Sloan, Jonathan Kehler

Sci Rep· March 2025

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Discovery of RXFP2 genetic association in resistant hypertensive men and RXFP2 antagonists for the treatment of resistant hypertension.
Shan-Shan Zhang, Lance Larrabee, Andrew H Chang, Sapna Desai, Lisa Sloan, Jonathan Kehler

Sci Rep· June 2024

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In vivo biodistribution and pharmacokinetics of sotrovimab, a SARS-CoV-2 monoclonal antibody, in healthy cynomolgus monkeys.
Tolulope A Aweda, Shih-Hsun Cheng, Stephen C Lenhard, Armin Sepp, Tinamarie Skedzielewski, Jonathan Kehler

Eur J Nucl Med Mol Imaging· February 2023

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Overcoming challenges associated with the bioanalysis of cysteine-conjugated metabolites in the presence of antibody-drug conjugates.
Andrew P Mayer, Hermes Licea-Perez, Sharon Boram, Kristen E Pannullo, Jonathan Kehler

Bioanalysis· September 2021

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Microflow UPLC and high-resolution MS as a sensitive and robust platform for quantitation of intact peptide hormones.
Zhuo Chen, Yun W Alelyunas, Mark D Wrona, Jonathan R Kehler, Matthew E Szapacs

Bioanalysis· June 2019

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Toward best practices in data processing and analysis for intact biotherapeutics by MS in quantitative bioanalysis.
John F Kellie, Jonathan R Kehler, Molly Z Karlinsey, Scott G Summerfield

Bioanalysis· December 2017

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A whole-molecule immunocapture LC-MS approach for the in vivo quantitation of biotherapeutics.
John F Kellie, Jonathan R Kehler, Thomas J Mencken, Richard J Snell, Charles S Hottenstein

Bioanalysis· October 2016

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Application of high-resolution MS for development of peptide and large-molecule drug candidates.
John F Kellie, Jonathan R Kehler, Matthew E Szapacs

Bioanalysis· February 2016

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Modify on the fly: triple quad to high resolution in support of a dermal clinical study requiring an ultra low LLOQ.
Chester L Bowen, Jonathan Kehler, Sharon Boram, Lee Abberley, Mathew Szapacs

Bioanalysis· February 2016

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Evaluation of organic anion transporting polypeptide 1B1 and 1B3 humanized mice as a translational model to study the pharmacokinetics of statins.
Laurent Salphati, Xiaoyan Chu, Liangfu Chen, Bhagwat Prasad, Shannon Dallas, Jonathan Kehler

Drug Metab Dispos· August 2014

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Comparison of the quantification of a therapeutic protein using nominal and accurate mass MS/MS.
Robert S Plumb, Gordon Fujimoto, Joanne Mather, Warren B Potts, Paul D Rainville, Jonathan R Kehler

Bioanalysis· March 2012

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Application of DBS for the quantitative assessment of a protein biologic using on-card digestion LC-MS/MS or immunoassay.
Jonathan Kehler, Neha Akella, David Citerone, Matthew Szapacs

Bioanalysis· October 2011

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Development and validation of a sensitive and selective UHPLC-MS/MS method for simultaneous determination of both free and total eicosapentaeonic acid and docosahexenoic acid in human plasma.
Chester L Bowen, Jonathan Kehler, Christopher A Evans

J Chromatogr B Analyt Technol Biomed Life Sci· November 2010

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Utility of dried blood spot sampling and storage for increased stability of photosensitive compounds.
Chester L Bowen, Matthew D Hemberger, Jonathan R Kehler, Christopher A Evans

Bioanalysis· November 2010

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Absolute quantification of a therapeutic domain antibody using ultra-performance liquid chromatography-mass spectrometry and immunoassay.
Matthew E Szapacs, James J Urbanski, Jonathan R Kehler, Robert Wilson, Sharon L Boram

Bioanalysis· September 2010

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Application of DBS for quantitative assessment of the peptide Exendin-4; comparison of plasma and DBS method by UHPLC-MS/MS.
Jonathan R Kehler, Chester L Bowen, Sharon L Boram, Christopher A Evans

Bioanalysis· August 2010

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Development of an in vivo preclinical screen model to estimate absorption and first-pass hepatic extraction of xenobiotics. II. Use of ketoconazole to identify P-glycoprotein/CYP3A-limited bioavailability in the monkey.
Keith W Ward, Gary J Stelman, Jayme A Morgan, Kelli S Zeigler, Leonard M Azzarano, Jonathan R Kehler

Drug Metab Dispos· February 2004

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