Publications by authors named "Jonathan Mitchem"

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Appraising a CREATEive Surgeon-Scientist Initiative: Impact and Future Directions.
Christopher J Neylan, Aron Bercz, Scott E Regenbogen, Emina H Huang, J Joshua Smith, Jonathan B Mitchem

Dis Colon Rectum· June 2025

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Searching for Signals of Success: Deciphering the Link Between Inflammatory Markers and Rectal Cancer Response to Neoadjuvant Therapy.
Jonathan B Mitchem, David Liska

Dis Colon Rectum· June 2025

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Differences in tumor-associated T-cell receptor repertoires between early-onset and average-onset colorectal cancer.
Ya-Yu Tsai, Kanika G Nair, Shimoli V Barot, Shao Xiang, Suneel Kamath, Jonathan B Mitchem

J Natl Cancer Inst· October 2024

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Targeting AKR1B10 by Drug Repurposing with Epalrestat Overcomes Chemoresistance in Non-Small Cell Lung Cancer Patient-Derived Tumor Organoids.
Kanve N Suvilesh, Yariswamy Manjunath, Yulia I Nussbaum, Mohamed Gadelkarim, Murugesan Raju, Jonathan B Mitchem

Clin Cancer Res· September 2024

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Identifying gene expression programs in single-cell RNA-seq data using linear correlation explanation.
Yulia I Nussbaum, K S M Tozammel Hossain, Jussuf Kaifi, Wesley C Warren, Chi-Ren Shyu, Jonathan B Mitchem

J Biomed Inform· June 2024

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Colorectal Cancer-Associated Myofibroblasts Exhibit Enhanced Angiogenin Expression and Signaling via the PLXNB2 Receptor.
Alexander Hu, Yulia I Nussbaum, Jonathan Mitchem, James Yoo

J Surg Res· April 2024

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Identification of Genomic Signatures for Colorectal Cancer Survival Using Exploratory Data Mining.
Justin J Hummel, Danlu Liu, Erin Tallon, John Snyder, Wesley Warren, Jonathan Mitchem

Int J Mol Sci· March 2024

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CREATEing Community for Colorectal Surgeon-Scientists.
Lillias H Maguire, Jonathan B Mitchem, J Joshua Smith

Dis Colon Rectum· April 2023

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Understanding common key indicators of successful and unsuccessful cancer drug trials using a contrast mining framework on ClinicalTrials.gov.
Shu-Kai Chang, Danlu Liu, Jonathan Mitchem, Christos Papageorgiou, Jussuf Kaifi

J Biomed Inform· March 2023

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Somatic mutation variant analysis in rural, resectable non-small cell lung carcinoma patients.
Jonathan B Mitchem, Amanda Miller, Yariswamy Manjunath, Mouadh Barbirou, Murugesan Raju

Cancer Genet· November 2022

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Immune-Related Gene Signatures to Predict the Effectiveness of Chemoimmunotherapy in Triple-Negative Breast Cancer Using Exploratory Subgroup Discovery.
Olha Kholod, William I Basket, Jonathan B Mitchem, Jussuf T Kaifi, Richard D Hammer

Cancers (Basel)· November 2022

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TBX21 Methylation as a Potential Regulator of Immune Suppression in CMS1 Subtype Colorectal Cancer.
Yuanyuan Shen, Yulia I Nussbaum, Yariswamy Manjunath, Justin J Hummel, Matthew A Ciorba, Jonathan B Mitchem

Cancers (Basel)· September 2022

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Identification of Immuno-Targeted Combination Therapies Using Explanatory Subgroup Discovery for Cancer Patients with EGFR Wild-Type Gene.
Olha Kholod, William Basket, Danlu Liu, Jonathan Mitchem, Jussuf Kaifi

Cancers (Basel)· September 2022

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Epigenetic Regulation of Cancer Immune Cells.
Diego M Avella Patino, Vijay Radhakrishnan, Kanve N Suvilesh, Yariswamy Manjunath, Guangfu Li, Jonathan B Mitchem

Semin Cancer Biol· August 2022

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Tumorigenic circulating tumor cells from xenograft mouse models of non-metastatic NSCLC patients reveal distinct single cell heterogeneity and drug responses.
Kanve N Suvilesh, Yulia I Nussbaum, Vijay Radhakrishnan, Yariswamy Manjunath, Diego M Avella, Jonathan B Mitchem

Mol Cancer· March 2022

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Circulating Tumor-Macrophage Fusion Cells and Circulating Tumor Cells Complement Non-Small-Cell Lung Cancer Screening in Patients With Suspicious Lung-RADS 4 Nodules.
Yariswamy Manjunath, Kanve Nagaraj Suvilesh, Jonathan B Mitchem, Diego M Avella Patino, Eric T Kimchi

JCO Precis Oncol· March 2022

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Single Circulating-Tumor-Cell-Targeted Sequencing to Identify Somatic Variants in Liquid Biopsies in Non-Small-Cell Lung Cancer Patients.
Mouadh Barbirou, Amanda Miller, Yariswamy Manjunath, Arturo B Ramirez, Nolan G Ericson, Jonathan B Mitchem

Curr Issues Mol Biol· February 2022

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Drug Repositioning and Subgroup Discovery for Precision Medicine Implementation in Triple Negative Breast Cancer.
Zainab Al-Taie, Mark Hannink, Jonathan Mitchem, Christos Papageorgiou, Chi-Ren Shyu

Cancers (Basel)· December 2021

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Explainable artificial intelligence in high-throughput drug repositioning for subgroup stratifications with interventionable potential.
Zainab Al-Taie, Danlu Liu, Jonathan B Mitchem, Christos Papageorgiou, Jussuf T Kaifi

J Biomed Inform· June 2021

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Immunity, immunotherapy, and rectal cancer: A clinical and translational science review.
Ebunoluwa E Otegbeye, Jonathan B Mitchem, Haeseong Park, Aadel A Chaudhuri, Hyun Kim

Transl Res· May 2021

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Current and Prospective Methods for Assessing Anti-Tumor Immunity in Colorectal Cancer.
Yulia I Nussbaum, Yariswamy Manjunath, Kanve N Suvilesh, Wesley C Warren, Chi-Ren Shyu, Jonathan B Mitchem

Int J Mol Sci· April 2021

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Circulating Giant Tumor-Macrophage Fusion Cells Are Independent Prognosticators in Patients With NSCLC.
Yariswamy Manjunath, Jonathan B Mitchem, Kanve N Suvilesh, Diego M Avella, Eric T Kimchi

J Thorac Oncol· September 2020

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F-FDG PET/CT total lesion glycolysis is associated with circulating tumor cell counts in patients with stage I to IIIA non-small cell lung cancer.
Diego M Avella, Yariswamy Manjunath, Amolak Singh, Chelsea B Deroche, Eric T Kimchi, Jonathan B Mitchem

Transl Lung Cancer Res· June 2020

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FOLFOX Chemotherapy Ameliorates CD8 T Lymphocyte Exhaustion and Enhances Checkpoint Blockade Efficacy in Colorectal Cancer.
Yue Guan, Sean G Kraus, Michael J Quaney, Mark A Daniels, Jonathan B Mitchem

Front Oncol· April 2020

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Tumor-Cell-Macrophage Fusion Cells as Liquid Biomarkers and Tumor Enhancers in Cancer.
Yariswamy Manjunath, David Porciani, Jonathan B Mitchem, Kanve N Suvilesh, Diego M Avella

Int J Mol Sci· March 2020

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